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40 Cards in this Set

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Normal Sodium (cation)

134-145 mEq/L

Normal Potassium (cation)

3.5-4.5 mEq/L

Normal Calcium (cation)

8-10.5 mEq/L

Normal Magnesium (cation)

1.5-2.5 mEq/L

Normal chloride (anion)

95-105 meq/L

Normal Bicarbonate (anion)

24-30 mEq/L

Normal Phosphate (anion)

2.5-4.5 mEq/L

Normal Sulfate (anion)

1 mEq/L

Normal Lactate (anion)

2 mEq/L

Normal Total Protein (anion)

6-8.4 mEq/L

major ICF cation

Potassium

major ECF cation

Sodium

Causes prominent U waves

Hypokalemia (decreased potassium)



also drugs as digoxin, sotalol, amiodarone, quinidine, procainamide

Causes peaked T-waves

Hyperkalemia (increased potassium) also hyppermagnesimia

Most common causes of hyponatremia

water intoxication, CHF, ARF, DKA, SIADH, diuretics, GI loss, diaphoresis, burns



S/S confusion, HA, poor concentration, anorexia, stupor, seizure, death

Most common causes of Hypernatremia

water loss, hypertonic tube feedings, diabetes insipidus, renal failure



S/S thirst, hyperpyrexia, dry mouth, lethargy, irritability, seizure, hallucinations

Most common causes of hypokalemia

diuretics, fluid loss, GI losses, hyperglycemia, hyperaldostronism (renal issue), bulimia


S/S fatigue, anorexia, muscle weakness, bradycardia, hypotension, depressed T wave, peaked P waves

Most common causes of hyperkalemia

Renal failure, cellular damage, DKA, SLE, Burns, Addison's disease (adrenal failure), medications (ACEs)


S/S weakness, N/V Flat P wave, elevated T wave, myalgia, bradycardia

Fluid Balance

Sodium reabsorption and excretion are driving forces of osmolarity

chloride

aids in digestion, buffering and osmotic pressure


major ECF anion and inverse with bicarb

Sodium and potassium pump

sodium pumped out of ICF and Potassium pumped into the ICF

solutes limited to ECF

sodium and glucose

changes in concentration produce osmotic gradients

water movements occur between the ECF and ICF, water moves from a low to high solute concentration

Effect of decreased sodium

water shifts from the ECF to ICF

Effect of increased sodium or hyperglycemia

water shifts out of the ICF (contracted) into the ECF

Osmolarity formula

2 x (Na) + (glucose/18) + (BUN/2.8)


Normal

Increased Chloride causes and s/s

ARF, ETOH, metabolic acidosis, aspirin OD, MM,



Deep breaths, lethargy, coma

Decreased Chloride causes and s/s

CKD, CHF, Addison's/adrenal suppression



shallow breathing, hypertonicity, tetany

Serum Ca- total Ca in blood

50% is ioninized or free and 50% is bound to protein (albumin)

calcium is regulated by

endocrine regulation via parathyroid hormone (PTH) and calcitonis

calcium reflects status of

Parathyroid, Thyroid, Renal function (protein, albumin, phosphorus), malignancies

increased calcium causes and s/s

dehydration, hyperthyroidism, hyperparathyrodism, malignancy (most common), immobilization, medications



calculi, bone pain, hypotonic muscles

Decreased calcium causes and s/s

Chronic kidney disease, ETOH, pancreatitis, hypoparathyroidism, ARF, elevated phosphate, done disorders, medication, previous thyroid surgery (most common)



arrythmia, paresthesia in face, hands and feet, muscle spasms, seizures

Phosphorous

main ICF anion, 12%-16% in blood, regulated by parathyroid, inverse excretory relation to calcium, acid-base, energy, bone growth, metabolism of glucose and lipids


higher in children due to bone growth

Magensium

Mainly an ICF cation, effects GI and renal systems, required in ATP, neuromuscular function, energy, clotting, reflects renal function, electrolyte status

increased Magensium causes and s/s

Dehydration, CKD, ARF, hypothyroidism, DKA, Medications


decreased BP, HR, RR and DTRs, sedation, Long PR and QT, wide QRS


decreased Magnesium causes and s/s

ETOH, GI/nutritional disease, decreased calcium, Kcl, medications (aminoglycocides) decreased magnesium leads to hypoparathyroidism adn a corresponding decrease in serum PTH and calcium


Arrythmia (VF, VT, long PR/QT), 3 Ts twitch, tremor, tetany

Alkaline Phosphatase

enzyme from bilary cells and osteoblasts, excreted by liver, slight increase with eldery and adolescents, Tumor Marker for osteosarcoma, breast and prostate Ca with mets to bone

Increased Alk Phos causes

normal child, pregnancy, elderly, obstructive jaundice, cone fractur, osteoblastic mets, drugs (estrogen, erythromycin)

Decreased Alk Phos causes

hypothyroidism, pernicious anemia, decreased phosphate levels, increased Vit D levels, malnutrition