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20 Cards in this Set
- Front
- Back
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PAF is liberated by PLA2. What are the effects of PAF
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activates & aggreates platelets
vasodilation up vascular permeability chemotaxis of PMLs bronchospasm (asthma) brocho hyperresponsiveness |
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Actions of TXA2
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platelet aggregation
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PGI2
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anatagonist to TXA2
relax bronchioles vasodilates cardiac sys hypotension cause pain inhibt acid secretion, up mucus |
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PGE2
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uterine contraction
patent ducturs arteriosis vasodilator inhibit effect of ADH (stops holding water, for hypertension) cause pain stomach protection |
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PGF2a
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uterine contraction
bronch contraction constriction pulm arteriers |
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PGD2
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contract bronchial SM
dilate cardiac sys at low conc, constrict at high |
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Leukotriens
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most potent bronciol constrictor
caues pain induce migration of inflammatory processes |
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cause uterine contraction
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PGE and PGF
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vasodilators
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PGI, PGE and PGD (low conc.)
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GI protection
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PGE and PGI
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platelet aggregation
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TXA
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bronchiol constrction
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PGF, PGD, LT's
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vasodilation to kidneys
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PGs
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cause pain
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PGE, PGI, LT's
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agonist for PGF2
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carboprost
uterine contraction |
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agaonsist of PGE2
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dinoprostone
used for uterine contraction |
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agonist for PGE1
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misoprostol
protects stomach with NSAIDS, dont use if pregnant (why?) |
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Where is PGF made?
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Uterus
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Where is PGE expressed
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blood vessels, kidney, skin, lungs, brain
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add this to NSAID tx to protect gastric mucosa
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Misoprostil
Increase mucous production to protect stomach |
