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4 Cards in this Set
- Front
- Back
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glucocorticoids |
inhibit expression of COX2,inhibit expression and action of PLA2(by d induced annexins) |
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NSAIDs |
inhibit activity of COX1 &COX2 |
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antileukotriene agents |
bronchial asthma,allergic rhinoconjuctivitis:zafirlukast,montelukast,pranlukasr(CysLT1 antagonist,v.safe drugs) ,zileuton |
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Omega 3 FA |
eicosapentanoeic acid(EPA):found m form of phospholipids in cold sea fish,when eaten it geta incoerated into membrane phospholipids which are cleaved by PLA2. TXA3 is formed which is less active dan TXA2 ;Decr. BP,antiplatelet effect,reduction of triglyceride levels. Also LTB5 is formed also less active;can be used as antiinflamatory in e.g rheumatoid athritis. |
