E4 Steroid And Peptide Hormones Review

Front 1

Gonadal Steroid Biosynthesis

Back 1

Cholesterol > Progesterone > Testosterone ----> aromatase > estradiol

Cholesterol > Progesterone > Testosterone -----> alpha reductase > DHT

Front 2

The biosynthesis of the gonadal steroid begins with the precursor ________.

Back 2

Cholesterol

Front 3

Testosterone is acted upon by the enzyme _________ and is converted into __________.

Back 3

Aromatase
Estradiol

Front 4

Testosterone acted upon by _________ is converted into __________.

Back 4

Alpha Reductase
Dihydrotestosterone (DHT)

Front 5

Is DHT more potent than testosterone?

Back 5

Yes

Front 6

GnRH receptors are tied to a _______.
(Gq/Gs/Gi/None Metabotropic)

Back 6

Gq

Front 7

FSH receptors are tied to a ________.
(Gq/Gs/Gi/None Metabotropic)

Back 7

Gs

Front 8

LH receptors are tied to a ________.
(Gq/Gs/Gi/None Metabotropic)

Back 8

Gs

Front 9

Cytokine receptors are tied to a ________.
(Gq/Gs/Gi/None Metabotropic)

Back 9

None Metabotropic

Front 10

GnRH, FSH, and LH receptors are metabotropic. They contain _________ transmembrane segments.

Back 10

Seven

Front 11

True or False:
Cytokine receptors are not metabotropic receptors.

Back 11

True

Front 12

Is Estrogen a Gonadal Steroid or an Adrenal Steroid?

Back 12

Gonadal Steroid

Front 13

is Progesterone a Gonadal Steroid or an Adrenal Steroid?

Back 13

Gonadal Steroid

Front 14

Is Mineralcorticoid a Gonadal Steroid or an Adrenal Steroid?

Back 14

Adrenal Steroid

Front 15

Is Androgen a Gonadal Steroid or an Adrenal Steroid?

Back 15

Gonadal Steroid

Front 16

Is Glucocorticoid a Gonadal Steroid or an Adrenal Steroid?

Back 16

Adrenal Steroid

Front 17

Estrogen receptors are tied to a _________.
(Gq/Gs/Gi)

Back 17

Gq

Front 18

Progesterone receptors are tied to a _______.
(Gq/Gs/Gi)

Back 18

Gq

Front 19

Androgen receptors are tied to a _______.
(Gq/Gs/Gi)

Back 19

Gs

Front 20

Glucocorticoid receptors are tied to a ______.
(Gq/Gs/Gi)

Back 20

Gs

Front 21

Mineralocorticoid receptors are tied to a _____.
(Gq/Gs/Gi)

Back 21

Gq

Front 22

Name all of the Estrogen receptors.

Back 22

Estradiol, Estriol, Clomiphene, Estrone, Tamoxifen

Front 23

Name all of the Androgen receptors.

Back 23

DHT, Flutamide, Testosterone.

Front 24

Name all of the Progesterone receptors.

Back 24

Mifepristone, Progesterone

Front 25

Name all of the Glucocorticoid receptors.

Back 25

Mifepristone, Cortisol, Corticosterone

Front 26

Name all of the Mineralocortocoid receptors.

Back 26

Aldosterone, Spironolactone

Front 27

What intracellular steroid hormone receptor does Estradiol belong to?

Back 27

Estrogen Receptors

Front 28

What intracellular steroid hormone receptor does DHT belong to?

Back 28

Androgen Receptors

Front 29

What intracellular steroid hormone receptor does Estriol belong to?

Back 29

Estrogen Receptors

Front 30

What intracellular steroid hormone receptor does Mifepristone belong to?

Back 30

Progesterone Receptors
Glucocorticoid Receptors

Front 31

What intracellular steroid hormone receptor does Cortisol belong to?

Back 31

Glucocorticoid Receptors

Front 32

What intracellular steroid hormone receptor does Aldosterone belong to?

Back 32

Mineralocorticoid Receptors

Front 33

What intracellular steroid hormone receptor does Clomiphene belong to?

Back 33

Estrogen Receptors

Front 34

What intracellular steroid hormone receptor does Flutamide belong to?

Back 34

Androgen Receptors

Front 35

What intracellular steroid hormone receptor does Corticosterone belong to?

Back 35

Glucocorticoid Receptors

Front 36

What intracellular steroid hormone receptor does Testosterone belong to?

Back 36

Androgen Receptors

Front 37

What intracellular steroid hormone receptor does Estrone belong to?

Back 37

Estrogen Receptors

Front 38

What intracellular steroid hormone receptor does Progesterone belong to?

Back 38

Progesterone Receptors

Front 39

What intracellular steroid hormone receptor does Tamixifen belong to?

Back 39

Estrogen Receptors

Front 40

What intracellular steroid hormone receptor does Spironolactone belong to?

Back 40

MIneralocorticoid Receptors

Front 41

Estrogen receptors are _________, they consist of alpha and beta receptors.

Back 41

Heterodimeric

Front 42

Estrogen receptor antagonists are used for the treatment of _________.

Back 42

Breast Cancer

Front 43

Anatrozole is an aromatase inhibitor which blocks the enzyme that produces _______.

Back 43

Estrogen

Front 44

What drug changes the lining of the uterus so that it is incompatible with implantation of a fertilized egg?

Back 44

Mifepristone

Front 45

Androgen receptors are _________, they consist of an ARA and an ARB receptor.

Back 45

Heterodimeric

Front 46

Name a ligand that is an alpha-reductase inhibitor.

Back 46

Finasteride

Front 47

Hormonal regulation of Estrus

Back 47

Arcuate N ; PVN ---->GnRH > Posterior Pituitary > Anterior Pituitary ------>FHS/LH > Ovaries

Front 48

Prolactin signals to ______.
(Gq/Gs/Gi/JAK/STAT)

Back 48

JAK (Janus Kinase)
STAT (Signal Transduction And Transcription Factor)

Front 49

Estrogen Antagonists

Back 49

Clomiphene
Tamoxifen

Front 50

Androgen Antagonist

Back 50

Flutamide

Front 51

Progesterone Antagonist

Back 51

Mifepristone

Front 52

Glucocortico Antagonist

Back 52

Mifepristone

Front 53

Mineralocorticoid Antagonist

Back 53

Spironolactone

Front 54

Minoxidil

Back 54

K ATP activator
Used to treat male-pattern baldness

Front 55

Receptors for ACTH are found in the _____.

Back 55

Adrenals