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22 Cards in this Set

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What do fat-soluble vitamins req for absorption?
a little bit of fat.
average daily dietary intake of a nutrient that is sufficient to meet the requirement of nearly all (97-98%) healthy persons = ?

amount estimated to meet the requirement of half of all healthy individuals in the population = ?
- RDA (recommended daily allowance)
- estimated average req (EAR)
highest daily intake that is likely to pose no risks of toxicity for almost all individuals; as intake above the UL increases, risk increases = ?

only established when an RDA cannot be determined; a nutrient either has an RDA or a(n) ___; based on observed nutrient intakes in a group of healthy persons
Tolerable upper intake level (TL)

Adequate intake (AI)
Given the problem, tell me what nutritional deficiency is associated:
- scurvy
- beriberi
- pellagra
- goiter, cretinism
- rickets
- pernicious anemia

Can minimal intakes prevent these issues?
Vit C
Thiamin
Niacin
Iodine
Vit D
B12

yes, except when due to non-nutritional causes.
Night blindness, xerophthalmia (dryness of the eye), Bitot’s spots (white accumulations of sloughed cells & secretions), keratomalacia (irreversible changes in eye and cornea)
- signs of deficiency in what?
Vit A.
bone/muscle pain, cirrhosis, dry itchy skin, conjunctivitis; excess beta-carotene may present orange skin, but is not toxic.
- excess of which vitamin group causes this?
- Vit A (retinoids & carotenoids)
hypercalcemia and calcification of soft tissues are sx of toxicity of which vitamin?
- can this be acheived through sun-exposure?
Vit D.
- no, only through supplementation.
Which rare deficiency is characterized by neurological problems associated with nerve degeneration in hands and feet?
Vit E deficiency.
What are the fx of Vit E?
- sources?
- toxicity sx?
potent antioxidant, immune function, DNA repair
- vegetable oils, nuts, leafy greens, fortified cereals

increased bleeding and impaired blood coagulation
What fat soluble vit is found in dark leafy greens, broccoli, cabbage?
- is this the only source?
- deficiency sx?
- There are no known tox sx of this vitamin; but what does over supplementation w/ menadione do?
- can interfere w/ which classes of drugs?
Vit K
- no, small amounts are made in GI via bacterial synthesis.
- various problems with blood coagulation (bleeding into skin/bruising, from nose, into stomach, etc), increased risk of fractures/reduced bone density; life-threatening bleeding in newborns in/around brain may occur (all newborns should be given a vit K injection)
- hemolytic anemia, hyperbilirubinemia, jaundice
- anticoags, like warfarin.
What are toxicity sx of Vit C?
- deficiency causes?
nausea/diarrhea.
- scurvy: bruising, gum and dental problems, dry hair and skin, and anemia; corkscrew hair, perifollicular bleeding (defective keratin synth disrupts hair growth)
Match B6, B12, and folate with the following deficiency sx:
- dermatitis, glossitis, convulsions
- megaloblastic anemia, diarrhea, fatigue
- megaloblastic anemia, peripheral nerve degeneration, glossitis.
- B6
- Folic acid
- B12
Asthmatic children are at risk of deficiency of which B complex vitamin?
B6.
Toxicity sx of B6? B12?
neuropathy

no known effects
Folic acid can correct the ____ cause by B12 deficiency, but not the ____.

Large amounts of folate can trigger damaging effects of what?
anemia

nerve damage.

B12 deficiency.
What is the usefulness of Copper?
- deficiency?
- toxicity?
enzyme cofactor; required for Fe absorption.
- low RBC and WBC, muscle spasms
- liv damage, kidney fail, coma, death
Deficiency in what trace mineral can lead to G intolerance? What is the normal fx of this mineral?
- sources?
Chromium.
- helps the body use insulin
- grains, nuts, cheeses.
growth retardation, impaired immune fxn, mental lethargy.... repeated skin infections, bullous-pustular dermatitis, diarrhea, alopecia

Think deficiency in which trace mineral?
Zinc
What is the difference between enriched and fortified?
enriched: adds back nutrients originally present but lost during food processing

fortified: adds nutrients to foods that weren't originally present.
What does the evidence say re: vitamin pills and cancer/CVD?
fails to prevent.
Do dietary supplements need to declare their active ingredients, expiration date, and/or known risks?

Any product that contains: vitamins, minerals, plant parts, amino acids, metabolites, or food components... is called a..?
no.

dietary supplement.
St. John's wort
Ginkgo biloba
panax ginseng
saw palmetto
feverfew
... all do what re: dangerous side effects?
increase bleeding tendency.