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42 Cards in this Set
- Front
- Back
Tell about AV node
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Potential Pacemaker
Filter CCB increses filter, AV node slow down conduction protects ventricles |
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Whic is fastest? AV or SA node
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SA node
(primary) |
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CCB are better for hypertention because ... don't affect its efficacity
CCB are said to be ... |
R, A, S
neutral because of that |
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Which CCB are for:
a) artery vasodilators b) cardiac c) for arrhytmias d)cardiac & vascular e) more tachycardia f) PE flush g)more bradycardia h)Constipation i) cerebral BV j) most prescribed k)massive edema l) sustained released m) headache is most common on... n) no cardiac depression is seen w |
a) artery vasodilators: Non-DHP
b) cardiac:Non-DHP c) for arrhytmias: Non-DHP d)cardiac & vascular: Non-DHP e) more tachycardia: DHP f) PE flush:DHP g)more bradycardia: h)Constipation: Non-DHP i) cerebral BV: nimodipine j) most prescribed: amlodipine k)massive edema: DHP l) sustained released: Nifedipine m) headache is most common on...DHP n) Amlodipine |
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Never give
Verapamil & ... together Verapamil & ... together |
clonidine (cardiact arrest & constip.)
antidiurinal |
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2 drugs that gives constipation
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Clinidine & verapamil (never together)
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SE of Non-DHP
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Dec HR
Dec contractility constipation excess slowing down |
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T or False
DHP dec myocardial contractility & dilates coronary arteries |
Non- DHP dec myocardial contractility, dec SA & Va node.
DHP's dilates small coronary art. & large arteries |
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... dilate large arteries
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O.N and DHP
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first line therapy for intolerance for Diuretics & BB
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CCB (all pt)
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Best antihypertensive for AA & BB in elderly
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CCB
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best drug for stable effort angina, CAD
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CCB
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Effect of CCB on:
1) Lipids, serum electrolytes, uric acid, or glucose insulin balance 2) renal dysfunction 3) diabetes mellitus 4) exercise 5) Long term treatment 6) proteinuria |
1) Lipids, serum electrolytes, uric acid, or glucose insulin balance- no adverse affect
2) renal dysfunction- good 3) diabetes mellitus- good 4) exercise- no effect 5) Long term treatment- reduces left ventricle hypertrophy more than diuretics but less than ACEI or alpha-methyldopa 6) decrease proteinuria in diabetes |
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What r the 4 determinants of drug consumption?
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HR
Contractility Preload Afterload |
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main symptoms of CHF
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Dyspnea
Shorten of breath arrhythmia |
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treatment for Angina
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BB: MAP
ON: NTG, mono/dinitrate (ora/sublingual) CCB: DHP Amlodipine, Nifedipine Non-DHP: Verapamil, diltiazem(never w BB) Dec preload, afterload, HR & contractility |
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Rebound is seen in
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Clonidine: Hypertension
ON: chest pain BB: HR |
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SE of ON
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Tachycardia
Palpitations flushing |
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Tolerance & dependence r seen in
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ON
Tolerance: efficacity dec w t Dependence: rebound chest pain, skip a dose |
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Drug for effort induce angina
Why |
BB: MAP
CCB: D & V (non-dhp) ON: oral/patch prn Dec HR, contractility, preload, afterload |
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Rest Angina
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BB + CCB + ON + Ranolazine
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T or F
IHD decreases myocardial infarction |
IHD decreases myocardial "oxygen"
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SE of Ranolazine
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Antiarrhytmic
Prolongs the QT intervals in ECG GI (nausea, constipation) |
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How does Ranolazine work?
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inhibit late Na current which decrease Ca inside the cell = decrease myocardiac consumption
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50% HF is due to what?
What about 35%? |
chronic IHD: poor function of the cardiac muscle (hypoxia & artherosclerosis)
Hypertension |
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Rx for HF
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target IHD & HT
must prevent less than 5 % rate of survival |
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Drugs that decrease mortality & morbidity
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ACEI/ARB
BB Aldo antagonist: spironolactone |
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HF drugs
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ACEI/ARB
digoxin diuretics Aldo antagonist: spir. BB: Carvedilol & Metoprolol |
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what r the age accelerators?
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HT
diabetes artherosclerosis |
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which has strongest cardiac depressant
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verapamil
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Non-DHP r contraindicated in
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pt w CHF, bradycardia, slow AV conduction
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reduce progression of macroalbuminemia
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ARB
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DOC for Effort induced Angina, 1rst line
triple therapy (BB+CCB+ON) is given for |
BB
severe angina |
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DOC for arrhytmia, 1rst line
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Verapamil
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DOC for pulmonary edema, 1rst line
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IV loop diuretic
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only one approve to treat essential HT in HF
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Carvedilol
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DOC for renal disease, 1rst line
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ACEI
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DOC for salt sensitive AA, 1rst line
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CCB
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DOC for CHF, 1rst line
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ACEI
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montherapy for systolic dysfunction w afib
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digoxin
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Ramipril and Trandopril work best after...
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MI
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Because of cardiac depression is best to use BB + which CCB
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DHP
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