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42 Cards in this Set

  • Front
  • Back
Tell about AV node
Potential Pacemaker
Filter
CCB increses filter, AV node slow down conduction protects ventricles
Whic is fastest? AV or SA node
SA node
(primary)
CCB are better for hypertention because ... don't affect its efficacity

CCB are said to be ...
R, A, S

neutral because of that
Which CCB are for:
a) artery vasodilators
b) cardiac
c) for arrhytmias
d)cardiac & vascular
e) more tachycardia
f) PE flush
g)more bradycardia
h)Constipation
i) cerebral BV
j) most prescribed
k)massive edema
l) sustained released
m) headache is most common on...
n) no cardiac depression is seen w
a) artery vasodilators: Non-DHP
b) cardiac:Non-DHP
c) for arrhytmias: Non-DHP
d)cardiac & vascular: Non-DHP
e) more tachycardia: DHP
f) PE flush:DHP
g)more bradycardia:
h)Constipation: Non-DHP
i) cerebral BV: nimodipine
j) most prescribed: amlodipine
k)massive edema: DHP
l) sustained released: Nifedipine
m) headache is most common on...DHP
n) Amlodipine
Never give
Verapamil & ... together
Verapamil & ... together
clonidine (cardiact arrest & constip.)


antidiurinal
2 drugs that gives constipation
Clinidine & verapamil (never together)
SE of Non-DHP
Dec HR
Dec contractility
constipation
excess slowing down
T or False
DHP dec myocardial contractility & dilates coronary arteries
Non- DHP dec myocardial contractility, dec SA & Va node.
DHP's dilates small coronary art. & large arteries
... dilate large arteries
O.N and DHP
first line therapy for intolerance for Diuretics & BB
CCB (all pt)
Best antihypertensive for AA & BB in elderly
CCB
best drug for stable effort angina, CAD
CCB
Effect of CCB on:

1) Lipids, serum electrolytes, uric acid, or glucose insulin balance
2) renal dysfunction
3) diabetes mellitus
4) exercise
5) Long term treatment
6) proteinuria
1) Lipids, serum electrolytes, uric acid, or glucose insulin balance- no adverse affect
2) renal dysfunction- good
3) diabetes mellitus- good
4) exercise- no effect
5) Long term treatment- reduces left ventricle hypertrophy more than diuretics but less than ACEI or alpha-methyldopa
6) decrease proteinuria in diabetes
What r the 4 determinants of drug consumption?
HR
Contractility
Preload
Afterload
main symptoms of CHF
Dyspnea
Shorten of breath
arrhythmia
treatment for Angina
BB: MAP
ON: NTG, mono/dinitrate (ora/sublingual)
CCB:
DHP Amlodipine, Nifedipine
Non-DHP: Verapamil, diltiazem(never w BB)

Dec preload, afterload, HR & contractility
Rebound is seen in
Clonidine: Hypertension
ON: chest pain
BB: HR
SE of ON
Tachycardia
Palpitations
flushing
Tolerance & dependence r seen in
ON

Tolerance: efficacity dec w t
Dependence: rebound chest pain, skip a dose
Drug for effort induce angina

Why
BB: MAP
CCB: D & V (non-dhp)
ON: oral/patch prn

Dec HR, contractility, preload, afterload
Rest Angina
BB + CCB + ON + Ranolazine
T or F
IHD decreases myocardial infarction
IHD decreases myocardial "oxygen"
SE of Ranolazine
Antiarrhytmic
Prolongs the QT intervals in ECG
GI (nausea, constipation)
How does Ranolazine work?
inhibit late Na current which decrease Ca inside the cell = decrease myocardiac consumption
50% HF is due to what?

What about 35%?
chronic IHD: poor function of the cardiac muscle (hypoxia & artherosclerosis)

Hypertension
Rx for HF
target IHD & HT
must prevent less than 5 % rate of survival
Drugs that decrease mortality & morbidity
ACEI/ARB
BB
Aldo antagonist: spironolactone
HF drugs
ACEI/ARB
digoxin
diuretics
Aldo antagonist: spir.
BB: Carvedilol & Metoprolol
what r the age accelerators?
HT
diabetes
artherosclerosis
which has strongest cardiac depressant
verapamil
Non-DHP r contraindicated in
pt w CHF, bradycardia, slow AV conduction
reduce progression of macroalbuminemia
ARB
DOC for Effort induced Angina, 1rst line


triple therapy (BB+CCB+ON) is given for
BB


severe angina
DOC for arrhytmia, 1rst line
Verapamil
DOC for pulmonary edema, 1rst line
IV loop diuretic
only one approve to treat essential HT in HF
Carvedilol
DOC for renal disease, 1rst line
ACEI
DOC for salt sensitive AA, 1rst line
CCB
DOC for CHF, 1rst line
ACEI
montherapy for systolic dysfunction w afib
digoxin
Ramipril and Trandopril work best after...
MI
Because of cardiac depression is best to use BB + which CCB
DHP