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11 Cards in this Set
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- Back
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8-year-old girl complained of a 2-wk history of severe sore throat, fever, abdominal pain, anorexia and a 5-pound weight loss; remarkable only for rheumatic fever; immunization utd included BCG vaccine; born in Iraq, moved to Iraq with her parents and sibling to Syria; lived on a farm – consumed raw milk..what caused this?
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Brucella
Francisella |
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Brucella are:
motile/nonmotile urease pos/neg nitrate pos/neg aerobic/anaerobic |
nonmotile
urease pos nitrate pos aerobic |
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how do you encounter Brucella?
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direct contact with infected animal or its by products (unpasteurized milk products)
DON'T FORGET THAT CHEESE can be made by this!! (especially in other countries) |
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this bug Forms granulomatous nodules in lymphatics, liver, spleen, bone marrow. No buboes or skin lesions. What is it? What is its major resistance?
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Brucella
Resist killing by macrophages |
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pt presents with malaise, fever, weakness, aches, and sweats
Fever tends to rise in afternoon (accompanied by drenching sweats) and falls during the night (undulant fever)...drank unpasteurized milk. |
Brucella
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best lab diagnosis for Brucella?
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EIA
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tx for Brucella?
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Doxycycline
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A previously healthy 25-year-old man traveled to Nantucket Island, Massachusetts, and installed an outdoor speaker system, a job that involved digging in the ground and laying cable. Ten days later, he presented to another facility with fever, pain in the left arm and axilla, and a "pimple" on the left thumb base, which became necrotic and was accompanied by papules and nodules ascending the wrist and forearm. What does he have?
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Ulceroglandular tularemia
caused by Francisella tularensis |
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what allows Franciscella tularensis to survive in the macrophage?
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LIPID RICH CAPSULE
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what is the most common clinical manifestation of Franciscella tularensis?
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ulceroglandular
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pt says they were skinning rabbits and now has some nodules climbing up the arm...what should you think? Tx?
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Francisella tularensis
DOC: streptomycin or gentamicin |
