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124 Cards in this Set
- Front
- Back
|
Tranylcypromine
|
(Parnate)
MAOI |
|
|
Phenelzine
|
(Nardil)
MAOI |
|
|
Isocarboxazid
|
(Marplan)
MAOI |
|
|
Selegiline
|
MAOI
|
|
|
Trazadone
|
(desyrel)
Atypical anti-depressant 5- HT2 blocker |
|
|
Bupropion
|
Atypical Anti-depressant
lowers seizure threshold increased NE and DA |
|
|
Mirtazpine
|
(Remeron)
3rd gen heterocyclic atypical antidepressant stimulates appetite, sedation |
|
|
maprotiline
|
Ludiomil
atypical antidepressant orthostatic hypotension |
|
|
phencyclidine
|
PCP
dissociative anesthetic blocks 5 HT, DA, and NE uptake nystagmus |
|
|
LSD
|
use haloperidol to block hallucinatory affects
|
|
|
cocaine
|
central nervous system stimulant
an appetite suppressant topical anesthetic. 5HT-NE-DA reuptake inhibitor |
|
|
Amphotericin B
|
Fungizone
Antifungal pore-forming via ergosterol binding |
|
|
Flucytosine
|
Antifungal
pyrimidine antimetabolite (like 5FU) used with Amp B or Itraconazole |
|
|
Ketoconazole
|
Antifungal
Azole Gynecomastia CYP450 inhibitor |
|
|
fluconazole
|
antifungal
azole CAN enter CNS |
|
|
itraconazole
|
antifungal
azole |
|
|
caspofungin
|
antifungal
echinocandin use for invasive aspergillus |
|
|
Griseofulvan
|
topical antifungal
for dermatophytes |
|
|
Nystatin
|
topical antifungal
for candida |
|
|
miconzole
|
topical antifungal
|
|
|
Econzole
|
topical antifungal
|
|
|
clotromizole
|
topical antifungal
|
|
|
terbinafine
|
topical antifungal
first line for dermatophyte, esp onychomycosis inhibits squalene epoxidase CI: pregancy |
|
|
pralidoxine
|
Cholinesterase reactivator
used for organophosphate poisoning |
|
|
parathion
|
organophosphate
|
|
|
chloroquine
|
aralen
anti-malarial acute attacks, not latent infxn |
|
|
quinine
|
quinamm
anti-malarial cinchonism (N/V, tinnits, vertigo, headahe, blurred vision) blackwater fever = rare complication |
|
|
mefloquine
|
lariam
anti-malarial |
|
|
pyramethamine
|
daraprim
antimalarial blood schizonticide combined with sulfadiazine for toxo |
|
|
pyrimethamine + sulfadoxine
|
fansidar
antimalarial |
|
|
atovagquone/proguanil
|
malarone
antimalarial |
|
|
primaquine
|
tissue schizonticide
antimalarial |
|
|
sodium stibogluconate
|
pentostam
antiprotozoal for leishmania (inhibs phosphofructokinase rxn) |
|
|
melarsoprol
|
mel B
antiprotozoal for typanpsoma brucei |
|
|
pentamidine
|
pentam
antiprotozoal for trypanosoma brucei |
|
|
nifurtimox
|
Lampit
antiprotozoal for Chagas (T. cruzi) |
|
|
suramin
|
antrypol
antiprotozoal for t brucei (no CNS) and Onchocerca volvulus |
|
|
paromomycin
|
Humatin
antiprotozoal, aminoglycoside for lumenal amebiasis |
|
|
iodoquinol
|
diodoquin
antiprotozoal for amebiasis |
|
|
bethanechol
|
urecholine
direct cholinomimetic works on bowel and bladder |
|
|
carbachol
|
carbastat
direct cholinomimetic |
|
|
pilocarpine
|
pilocar
direct cholinomimetic glaucoma (crisis), crosses BBB |
|
|
methacholine
|
mecholyl
direct cholinomimetic challenge test for asthma/bronchial hyperreactivity |
|
|
isoflurophate, echothiphate, parathion
|
organophosphates
indirect cholinomimetic |
|
|
physostigmine
|
eserine
indirect cholinomimetic used in OD of atropine, phenothiazines, TCAs can enter the BBB |
|
|
neostigmine
|
prostigmin
indirect cholinomimetic |
|
|
edrophonium
|
enlon
indirect cholinomimetic used for dx of MG |
|
|
pyridostigmine
|
mestinon
indirect cholinomimetic long-term MG tx |
|
|
atropine
|
cholinergic antagonist
muscarinic antagonist anti-DUMBBELSS dry as bone, hot as a hair, red as a beet, blind as a bat, mad as a hatter |
|
|
scopolamine
|
cholinergic antagonist
nonselective muscarinic blocker used for motion sickness |
|
|
homatropine
|
cholinergic antagonist
topical for mydriasis and cycloplegia |
|
|
cyclopentolate
|
cyclogyl
cholinergic antagonist topical for mydriasis and cycloplegia |
|
|
tropicamide
|
cholinergic antagonist
topical for mydriasis and cycloplegia |
|
|
tubocurarine
|
cholinergic antagonist
nondepolarizing neuromuscular blockade |
|
|
pancuronium
|
cholinergic antagonist
nondepolarizing neuromuscular blockade |
|
|
atracurium
|
cholinergic antagonist
nondepolarizing neuromuscular blockade |
|
|
vecuronium
|
cholinergic antagonist
nondepolarizing neuromuscular blockade |
|
|
succinylcholine
|
cholinergic antagonist
DEPOLARIZING neuromuscular blocker rapid intubation DON'T USE WITH HALOTHANE |
|
|
nicotine
|
cholinergic antagonist
ganglionic blocker (initial ganglionic excitation) |
|
|
hexamethonium
|
cholinergic antagonist
ganglionic blocker (no initial stimulation) |
|
|
mecamylamine
|
cholinergic antagonist
ganglionic blocker (no initial stimulation) |
|
|
trimethaphan
|
cholinergic antagonist
ganglionic blocker (no initial stimulation) |
|
|
phenylephrine
|
sympathomimetic
alpha 1-selective direct-acting agonist vasoconstriction, nasal decongestant |
|
|
methoxamine
|
sympathomimetic
alpha 1 -selective direct-acting agonist for hypOtension and paroxysmal atrial tachycardia (PAT) |
|
|
clonidine
|
sympathomimetic
alpha-2-selective direct-acting agonist CNS, reduces sympathetic outflow from the brain used for HTN, benzo/opiate withdrawal, diarrhea in DM pts with neuropathy |
|
|
methyldopa
|
sympathomimetic
alpha-selective direct-acting agonist used for HTN in pregnancy |
|
|
dobutamine
|
sympathomimetic
beta-1-selective agonist, some beta 2 axn increases HR, inotropy |
|
|
isoproterenol
|
sympathomimetic
beta-agonist (both 1 and 2) for tx of heart block and bradycardia |
|
|
albuterol
|
sympathomimetic
beta-2-agonist (some beta 1 at high doses) inhaled for bronchospasm |
|
|
metaproterenol
|
sympathomimetic
beta-2-agonist inhaled for bronchospasm |
|
|
salmeterol
|
sympathomimetic
beta-2-agonist inhaled for bronchospasm |
|
|
terbutaline
|
sympathomimetic
beta-2-agonist oral or subQ for bronchospasm |
|
|
epinephrine
|
sympathomimetic
directly-acting alpha and beta agonist increased systolic BP bc alpha axn, but if given alpha blocker, will lower BP bc beta activity |
|
|
norepinephrine
|
sympathomimetic
directly-acting alpha and beta agonist alpha>beta1, no beta 2 stimulation last line agent in shock tx, causes several vasoconstriction |
|
|
dopamine
|
sympathomimetic
directly-acting alpha 1, beta1 and 2 agonist (as well as DA receptors) used for shock, ARF, acute CHF |
|
|
tyramine
|
sympathomimetic
indirectly-acting agonist by-product of tyrosine metabolism, causes HTNsive crisis in someone on MAOIs |
|
|
amphetamine
|
sympathomimetic
indirectly-acting agonist releases stores of presynaptic NE and DA |
|
|
ephedrine
|
sympathomimetic
both direct/indirect agonist stimulates NE release and acts directly on alpha and beta receptors |
|
|
metaraminol
|
sympathomimetic
both indirect/direct agonist releases NE from presynaptic terminal and can directly stimulate alpha receptrs |
|
|
Tranylcypromine
|
(Parnate)
MAOI |
|
|
Phenelzine
|
(Nardil)
MAOI |
|
|
Isocarboxazid
|
(Marplan)
MAOI |
|
|
Selegiline
|
MAOI
|
|
|
Trazadone
|
(desyrel)
Atypical anti-depressant 5- HT2 blocker |
|
|
Bupropion
|
Atypical Anti-depressant
lowers seizure threshold increased NE and DA |
|
|
Mirtazpine
|
(Remeron)
3rd gen heterocyclic atypical antidepressant stimulates appetite, sedation |
|
|
maprotiline
|
Ludiomil
atypical antidepressant orthostatic hypotension |
|
|
phencyclidine
|
PCP
dissociative anesthetic blocks 5 HT, DA, and NE uptake nystagmus |
|
|
LSD
|
use haloperidol to block hallucinatory affects
|
|
|
cocaine
|
central nervous system stimulant
an appetite suppressant topical anesthetic. 5HT-NE-DA reuptake inhibitor |
|
|
Amphotericin B
|
Fungizone
Antifungal pore-forming via ergosterol binding |
|
|
Flucytosine
|
Antifungal
pyrimidine antimetabolite (like 5FU) used with Amp B or Itraconazole |
|
|
Ketoconazole
|
Antifungal
Azole Gynecomastia CYP450 inhibitor |
|
|
fluconazole
|
antifungal
azole CAN enter CNS |
|
|
itraconazole
|
antifungal
azole |
|
|
caspofungin
|
antifungal
echinocandin use for invasive aspergillus |
|
|
Griseofulvan
|
topical antifungal
for dermatophytes |
|
|
Nystatin
|
topical antifungal
for candida |
|
|
miconzole
|
topical antifungal
|
|
|
Econzole
|
topical antifungal
|
|
|
clotromizole
|
topical antifungal
|
|
|
terbinafine
|
topical antifungal
first line for dermatophyte, esp onychomycosis inhibits squalene epoxidase CI: pregancy |
|
|
pralidoxine
|
Cholinesterase reactivator
used for organophosphate poisoning |
|
|
parathion
|
organophosphate
|
|
|
chloroquine
|
aralen
anti-malarial acute attacks, not latent infxn |
|
|
quinine
|
quinamm
anti-malarial cinchonism (N/V, tinnits, vertigo, headahe, blurred vision) blackwater fever = rare complication |
|
|
mefloquine
|
lariam
anti-malarial |
|
|
pyramethamine
|
daraprim
antimalarial blood schizonticide combined with sulfadiazine for toxo |
|
|
pyrimethamine + sulfadoxine
|
fansidar
antimalarial |
|
|
atovagquone/proguanil
|
malarone
antimalarial |
|
|
primaquine
|
tissue schizonticide
antimalarial |
|
|
sodium stibogluconate
|
pentostam
antiprotozoal for leishmania (inhibs phosphofructokinase rxn) |
|
|
melarsoprol
|
mel B
antiprotozoal for typanpsoma brucei |
|
|
pentamidine
|
pentam
antiprotozoal for trypanosoma brucei |
|
|
nifurtimox
|
Lampit
antiprotozoal for Chagas (T. cruzi) |
|
|
suramin
|
antrypol
antiprotozoal for t brucei (no CNS) and Onchocerca volvulus |
|
|
paromomycin
|
Humatin
antiprotozoal, aminoglycoside for lumenal amebiasis |
|
|
iodoquinol
|
diodoquin
antiprotozoal for amebiasis |
|
|
bethanechol
|
urecholine
direct cholinomimetic works on bowel and bladder |
|
|
carbachol
|
carbastat
direct cholinomimetic |
|
|
pilocarpine
|
pilocar
direct cholinomimetic glaucoma (crisis), crosses BBB |
|
|
methacholine
|
mecholyl
direct cholinomimetic challenge test for asthma/bronchial hyperreactivity |
|
|
isoflurophate, echothiphate, parathion
|
organophosphates
indirect cholinomimetic |
|
|
physostigmine
|
eserine
indirect cholinomimetic used in OD of atropine, phenothiazines, TCAs can enter the BBB |
