• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

Card Range To Study

through

image

Play button

image

Play button

image

Progress

1/51

Click to flip

Use LEFT and RIGHT arrow keys to navigate between flashcards;

Use UP and DOWN arrow keys to flip the card;

H to show hint;

A reads text to speech;

51 Cards in this Set

  • Front
  • Back
mechlorethamine?
Which formualtion caused more contact dermatitis?
Topical nitrogen mustard, or mechlorethamine, is an antineoplastic agent which works via alkylation thereby inhibiting DNA synthesis. Allergic contact dermatitis occurs in two-thirds of patients who are treated with topical nitrogen mustard in aqueous solution, but occurs in less than 5% of patients treated with the ointment based preparation.
Increase MTX levels
Displacement of Plasma Proteins:
1. Tetracyclines
2. Phenytoin
3. Pehnothiazines
4. Chloramphenicol
5. NSAIDs
6. Salicylates
7. Sulfonamides
AGEP
cepahlosporins
mercury
CREAM
SEMISOLID EMULSION OF OIL AND WATER
gel
semisolid emulsion
lotion
liquid aqueous or alcohol based and salt solution
ointment
semisolid grease/oil w powder
paste
ointment with powder
mc side effect of imuran
bm suppression
malathion
organophosphate cholinesterase inhibitor
what medication with imuran will lower IUD effectiveness
motrin
Fomiversen
anti-sense antivirals
CMV retinits w AIDS
mc side effects occular inflammation and increase intraocular pressure
Sulsobenzone
sunscreen
UVA blocker
Alefacept
human LFA-3/IgG Fusion protein blocks LFA-3 on APC and CD-2 on T cell
prevents T cell stimulation
destroys activated memory T cells
2-mercptoethanesulfonate
MENSA
Ivermectin FDA approved? MOA?
FDA-approved for the treatment of strongyloides and onchocerciasis.

blocks glutamate-gated chloride ion channels
worm or mite nerve and muscle paralysis
SCLE
piroxicam
glyburide
dapsone MOA?
inhibits halide-myeloperoxidase system
impaired respiratory burst and tissue damage
class B
no risk to humans, may have risk to animals
or
no risk to animals, but no studies on humans
thalidomide peak toxicity GA?
21-36 days
aquired brachia dyschromatosis
ACE inhibitors

asymptomatic gray-brown pathces with geographic borders w hypopigmented macules on dorsum forearms bilateral, middle age women
1,4 dihydroxybenzene
hydroquionone
Gold
stomatitis
chelitis
LP
PR
Thio-TEPA
alkylating agent
pruritus, urticaria, angioedema, hyperpigmenation occluded areas
Busulfan
Addison's like hyperpigmentation
Hyperpigmentation teeth with discoloration at the gingival margins
cyclophosphamide
Intense flushing
dacarbazine
carmustine
alternating colors of hair
flag sign
MTX
drug induced SLE
isonaizid
penicillamine
anticonvulsants
Catagory X drugs
finasteride
5-FU
flutamide
MTX
stanozolol
thalidomide
silymarin
antioxidant
retinoids keratinocyte differentiation
increase KH granules
increase Filaggrin
Increase KIF
Increase Odland body secretion of lipids
Inhibit ornithine decarboxylase
Thiabendazole
inhibits fumarate reductase

cutaneous larva migrans
larva currens
Lindane
organochloride
peremethrin
disbles sodium transport channels
podophyllotoxin
podofilox or condolox
anti-mitotic agent
reversibly binds tubulin
metaphase

podophyllin same MOA but contains kaempero and quercetin potent mutagens
Cantharin
phosphodiesterase inhibitor
cellcept binds?
iron
do not take cellcept with iron, decrease absorption
penile calcification
Bleomycin
glucocorticosteroids MOA
decrease AP-1, NF-kB
most likely congenital defect with isotretinoin therapy?
cranial synostosis
P450 metabolized
carbamazepine
theophylline
warfarin
digoxin
methylprednisolone
methyl antranilate
UVA
Padimate O
PABA derivateive
UVB
creams
oil in water
gels
semisolid emulsion in alcohol base
lotions/solutions
powder in water
foams
liquid and or solid in gaseous material
bacitracin
polypeptide antibotic
Tracy stain of Bacillus subtilis
inhibits bacterial cell wall sytnehsis by complexing with carrier protein C55-prenol pyrophosphatase involved in transfer of polysaccharides, liposaccharides, and peptidoglycans
most dramatic decrease in bone density with corticosteroids
young men
trabecular bone ribs and vertebrae > corticol long bones
most demineralization first 6 -12 mths
DACTINOMYCIN
ACUTE SUPERFICIAL FOLLICULITIS OF FACE AND TRUNK