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42 Cards in this Set

  • Front
  • Back

Jim Sloan's initial experience with cocaine use did not affect him. What triggered his increased cocaine use?

The continued use of free base crack. He enjoyed the rush then he continued use.

According to Conan Kortnetsky, an area of the brain is known to be involved in reward for many behaviors. Which brain area?

The Nucleus Accumbens is responsible for the pleasure part of the brain. This includes rewards for sex, food and drug use.

How is electrical stimulation of the brain different from natural reinforcers?

No satiation. We do not become full. We keep doing the behavior.

What kind of evidence demonstrates that electrical stimulation of the brain is a strong reinforcer?

because drug addicts will engage in illeagle behavior or painful behavior in order to recieve a high.

what other kinds of stimuli act on the nucleus accumbens?

sex, food, anything pleasurable.

Which neurotransmitter is involved in the rewarding effects of drugs and other rewarding stimuli?

Dopamine. (Why heroin is called "dope")

If the nerve cells that release this neurotransmitter are destoryed how are responses to reinforcing stimuli effected?

the person will loose desire to continue use. No reward.

What learning phenomenea may have contributed to vietnam vet nate chambers use of heroin during the war?

operant conditioning? (ask about this)


self-medication

what was hans kosterlitz secret idea?

morphine substance in the brain


changing muscle in the brain=heroin effect


natural morphine

liza harrison became addicted to what kind of tranquilizing drug?

valium-benzodiasopines

what learning phenomenea contributed to liza's continued use?

pavlovian conditioning? (ask about this)

what change in drug receptor populations contribute to symptoms of withdrawl when one abstains from using an addictive drug?

more receptors bind to the sites as the dosage increases resulting in a reduction of excitability



when one abstains they expierence tolerance and withdrawl from lack of binding.

what was the surprise when vietnam vets returned from vietnam?

several were addicts when they were in vietnam but less than 50% used when they got back and less than 50% of that continued use.

What is the relationship of p3 to al groom? what occurres in his offspring?

deficit of p3 in al groom


p3 missing in alcoholic fathers


deficits in cognition


sensory deficits


inherits the p3 deficit and is more likley to become addicted when the child grows older

what learning terminology describes jim sloans triggers for cocaine craving?

see perniphelia (ask about this)

the process used to treat sloans triggers were?

desensitization

how did sloans body temp change the first expierament to the current one in the video?

his body temp dropped to 76 degrees. This time it stayed at 97.

Naloxone sensitive

blocks stress

acupuncture

objectivly reduces pain

placebo effect

not imaginary; mediated by opioid.


when one is given a drug and immediately feels the effect or may have not been given a drug and they feel effects.

what blocks opioid mediated analgesia?

naloxone

Operant Learning

attempt to change enviornment


controlled by consequences


aquisition and maitence

Pavlovian conditioning (respondant of operant learning)

involuntary behavior


triggered by external events


learned reflxes


motivation

naloxone

blocks stress induced analygesia

reaquisition

pair ques with unconditional stimilus

unconditional stimulus

biologically important


survival value


(food, water, sex)

unconditional response

reflexive response


automatic


(saliva, stomach growling)

conditional stimuli (cs)

initially neutral


becomes a signal/que

conditional response (cr)

learned response


elicited by conditional stimuli

spontaneous recovery

passage of time

disinhibition

cs in new context

renewal effect

extinction in different context than aquasition

reaquasition

cr reestablished

a process

physiological disturbance


homeostatic disturbance

b process

compensatory response


observed response

a+b processes


net effects

salience

how important it is in lifes

sensitization

increased drug effects

appetitive stimulus

something you want

adversive stimulus

oppsite of what you want

positive reinforcement

nice effect

negitive reinforcement

subtracting bad