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104 Cards in this Set
- Front
- Back
Diphenhydramine Class
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Antihistamine
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Diphenhydramine Blocks what receptor sites?
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H1
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Diphenhydramine Duration?
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6-12 hrs
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Diphenhydramine Indications?
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Allergic Reaction, Anaphylaxis, Acute extraphyramidal (dystonic) reactions
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Diphenhydramine Contraindications?
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Pts taking MAO inhibitors, Hypersensitivity, Narrow-angle glaucoma, newborns and nursing mothers
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Diphenhydramine Adult Dosage? Max Dosage?
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10-50mg IM, slow IV every 6-8hrs (max 400mg/day)
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Methylprednisolone trade name
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Solu-Medrol
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Methylprednisolone Class
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Glucocorticoid -
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Methylprednisolone Discription? What does it stimulate?
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synthetic steroid that suppress acut and chronic inflamation
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Solu-medrol onset
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1-2 hrs
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Solu-medrol indication
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anaphylaxis, spinal cord injury, bronchodialter-unresponsive asthma
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Solu-medrol dose
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40-125 mg iv range
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Hydroxyzine trade name
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Atarax, Vistaril
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Hydroxyzine class
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Antihistamine, antiemetic, antianxiety
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Hydroxyzine action
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CNS depression, tranquilizing effects
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Hydroxyzine onset
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IM 15-30 min.
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Hydroxyzine dose
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25-100 mg deep IM
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Hydroxyzine how supplied
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25-50 mg/ml 1 ml vials
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Hydroxyzine indication
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NV, anxiety, motion sickness
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Phenytoin trade name
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Dilantinl
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Phenytoin class
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Anticonvulsant, antidysrhythmic
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Phenytoin description
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Control grand mal and focal seizure by inhibiting sodium influx as well as TX for atrial and ventrical dysrhythmia
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Phenytoin onset
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20-30 min
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Phenytoin supplied
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50 mg/ml in 2 & 5ml ampules, use in-line filter
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Phenytoin dose seizure
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IV: 1000mg slow puch
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promaethazine trade name
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Phenergan
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promaethazine class
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antiemetic, phenothiazine, antihistamine
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promaethazine onset
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less 1 min IV
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promaethazine indication
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NV, potentiate analgeics, motion sickness
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promaethazine contrindiction
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reye syndrom
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promaethazine supplied
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25,50 ml/ml 1 ml ampules
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promaethazine dose
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IV/IM 12.5-25 mg
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Trade name midazolam hydrochloride
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Versed
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midazolam hydrochloride class
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benzo, sedative
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midazolam hydrochloride description
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Induces sleep, decrease anxiety and impairs memory retention
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midazolam hydrochloride onset
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1-3 min IV
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midazolam hydrochloride indication
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premedicat et or cardioversion, anxiety
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midazolam hydrochloride supplied
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2,5,10ml vials (1,g/ml)
1,2,5ml vials (5mg/ml) |
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midazolam hydrochloride dose
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2.5-5 mg slow push 2-3 min.
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Haloperidol trade name
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Haldol
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Haloperidol Class
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ANtipsychotic
butyrophenones treat various psychiatric disorders such as schizophrenia |
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Haloperidol description
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butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics.
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Haloperidol Onset
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IV: 10-20 minutes
IM: 30-60 minutes |
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Haloperidol indication
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Acute psychotic episode
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Haloperidol supplied
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2-5 ml IM not recomended for ped
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thiamine trade name
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(Betaxin®), vitamin B1
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Thiamine class
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vitamin
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Thiamine description
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Thiamine combines with adenosine triphosphate (ATP) to form thiamine pyrophosphate (TPP) coenzyme, a necessary component for carbohydrate metabolism.
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Thiamine onset
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< 1 min
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Thiamine indication
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Prior to the administration of D50 in hypoglycemia when alcohol abuse and/or malnourishement is suspected.
Delirium tremens Beriberi (rare) Wernicke’s encephalopathy |
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Thiamine supplied
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1000 mg in 10 ml vial (100 mg/ml)
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Thiamine dose
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IV/IM: 100 mg slow push
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mannitol trade name
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Osmitrol®)
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mannitol class
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Osmotic Diuretic
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mannitol Onset
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Diuretic effect: 1-3 hours
Reduction of ICP: 15 min |
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mannitol indication
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Cerebral edema
Other causes of increased intracranial pressure (space occupying lesions) Rhabdomyolyses (myoglobinuria) Blood transfusion reactions |
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mannitol description
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it promotes the movement of fluid from the intracellular into the extracellular space. In emergency care, mannitol is used in the treatment of closed head injury to decrease cerebral edema and intracranial pressure, and in the promotion of urinary excretion of toxic substances.
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mannitol supplied
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250 and 500 ml of a 20% solution for IV infusion (200 mg/ml), 25% solution in 50 ml for slow IV push.
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mannitol dose
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IV Infusion: 0.5 g/kg in a 20% solution over 20 minutes.
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lorazepam trade name
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(Ativan®)
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lorazepam description
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Raises seizure threshold and stops active seizures by hyperpolarizing neural membranes via enhancement of GABA (an inhibitory neurotransmitter) activated chloride channels.
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lorazepam Class
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Benzodiazepine
Sedative/Hypnotic |
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lorazepam onset
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1-5 min
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lorazepam indication
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Initial control of status epilepticus or severe recurrent seizures.
Anxiety |
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lorazepam supplied
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2 and 4 mg/ml concentration in 1 ml vials
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lorazepam dose
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Prior to IV administration, lorazepam must be diluted with an equal volume of sterile water or sterile saline. When given IM, lorazepam is not to be diluted.
IV/IM: 1-4 mg slow (over 2-10 min), may be repeated in 15-20 minutes. Max dose 8 mg. |
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diazepam trade name
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(Valium®)
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diazepam class
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Benzodiazepine
Sedative – hypnotic Anticonvulsant |
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diazepam description
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Diazepam is a frequently prescribed medication to treat anxiety and stress. In emergency care, it is used to treat alcohol withdrawal and grand mal seizure activity.
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diazepam onset
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IV: Rapid
IM: 15-30 minutes ET: Rapid |
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diazepam indication
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Acute anxiety states
Acute alcohol withdrawal Sedation Seizure activity Premedication prior to countershock or TCP |
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diazepam supplied
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5 mg/ml vials, ampules, Tubex
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diazepam dose
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5 mg over 2 min (up to 10 mg for most adults) IV every 10 –15 min prn.
Cardioversion:5-15mg IV, 5-10 minutes prior to procedure |
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dexamethasone trade name
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(Decadron®, Hexadrol®)
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dexamethasone class
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Clucocorticoid
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dexamethasone onset
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4-8 hours
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dexamethasone indication
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Cerebral edema (controversial)
Endocrine, rheumatic, hematologic disorders Allergic states |
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dexamethasone dose
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There is considerable variance in recommended doses. The usual range in emergency care is 4-24 mg IV. Some physicians may prefer significantly higher doses (up to 100 mg)
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succinylcholine trade name
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(Anectine®)
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succinylcholine class
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Neuromuscular Blocker (Depolarizing)
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succinylcholine mechanism
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Succinylcholine has the briefest duration of action of all neuromuscular blocking drugs, making it a drug of choice for such procedures as terminating laryngospasm, endotracheal intubation, and electroconvulsive shock therapy.
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succinylcholine indication
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To facilitate intubation
Terminating laryngospasm Muscle relaxation |
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succinylcholine onset
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less 1 min
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succinylcholine duration
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less 5 min
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succinylcholine supplied
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40 mg in 2 ml ampule (20 mg/ml)
100 mg in 5 ml ampule (20 mg/ml) Multidose vial |
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succinylcholine
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IV: 1.5mg/kg rapid, repeat once if needed.
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epinephrine trade name
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(Adrenalin®)
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epi class
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sympothomimietic
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epi description
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Epinephrine stimulates alpha, beta 1 and beta 2 adrenergic receptors in dose-related fashion. Rapid injection produces a rapid increase in blood pressure, ventricular contractility, and heart rate. In addition, epinephrine causes vasoconstriction in the arterioles of the skin and mucosa. It antagonizes the effects of histamine by decreasing its release and decreasing membrane permeability.
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Epi onset
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(SQ) 5-10 minutes
(IV, ET) 1-2 minutes |
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epi duration
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5-10 min
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epi indication
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Bronchoconstriction
Anaphylaxis All forms of cardiac arrest Profound symptomatic bradycardia |
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epi supplied
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1mg/ml (1:1,000)
0.1mg/ml (1:10,000) ampule and prefilled syringes |
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epi dose
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1mg IV or 2 – 2 ½ times the IV dose via ET, repeat every 3-5 minutes.MOD ALER Reaction 0.3-0.5mg (1:1,000) SQ
ANAPHLAXIS0.05-0.5 mcg/kg/min INFUSION |
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Prochlorperazine trad name
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compazine
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compazine indication
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Compazine is used to control severe nausea and vomiting. It is also used to treat symptoms of the mental disorder schizophrenia, and is occasionally prescribed for anxiety.
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Prochlorperazine class
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antipsychotic, antiemetic, antianxiety agent
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Prochlorperazine indication
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Control NV and manifestion of psychtoic episode
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Prochlorperazine supplied
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tablets 5,10,25mg
5mg/5ml injection |
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Dose Prochlorperazine
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5-10mg PO for both antiemetic and psychiatry
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The drug of choice for severe allergic reaction and anaphylaxis? What is the dose?
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Epi: Mild reaction 0.3-0.5mg of 1:1,000. Severe reaction 0.3-0.5mg IV 1:10,000 repeat 3-5 minutes
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Antihistamines drug of choice____and dose
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diphenhydramine The dosage is 25-50 mg IV or Im
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The beta agonist agent for bronchospasm?
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0.5mL of albuterol in 3 ml of normal saline
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Other medication for management of anaphylaxis include:
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Solu-medrol - supress inflammation
Vasopressors - Dopamine - inhance cardiac output |