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15 Cards in this Set

  • Front
  • Back
Drugs

Most common treatment of Sz


Antipsychotics being taken in the form of syrup, injections or tablets.


May be used in short term or long term

Typical antipsychotics

Clorpromazine


Dopamine hypothesis links


Antagonists in the system, reducing the action of the neurotransmitter by blocking dopamine receptors in the brain


Often used to calm patients

Atypical antipsychotics

Clozapine binds to dopamine receptors in the same way but also binds to serotonin and glutamate.


Improves mood and reduces depression


Often given to suicidal Sz patients


Fatal side effects so Risperidone introduced

Evidence for effectiveness

Thornley et. al. placebo


Showed that those taking drugs functioning was improved


Support for benefits of atypical antipsychotics

Fatal side effects

Long term use resulting in tardive dyskinesia caused by dopamine supersensitivity.


Neuroleptic malignant syndrome, regulation of body systems prevented


Atypical created to reduce these side effects but still need regular checks on blood

Depends on dopamine hypothesis

Evidence to show that this explanation is not complete and mixed knowledge on whether Sz is caused by too high or too low levels of dopamine


Modern knowledge suggests these drugs shouldn't work

The interactionist approach

Acknowledges the influences of biological, psychological and societal factors in the onset of Sz


Genetic vulnerability, stress and daily hassles

Diathesis-stress model
Both a vulnerability to Sz and a stress trigger are necessary in order to develop the condition
Meehl

Original model


Diathesis was completely genetic and the result of a schizogene


If a person does not have this gene they will never have Sz

Modern diathesis

Many genes increase vulnerability


Psychological trauma also now causing vulnerability rather than being the stressor


Severe trauma in young age causing HPA system to become overactive making stress more damaging

Modern stress

Modern definition is anything that could trigger Sz


Research into onset after usage of cannabis


Cannabis interferes with the dopamine system

Treatment
Combination of drugs and psychological treatments such as therapy
Evidence for the role of vulnerability and triggers

Tienari investigated vulnerability and parenting style


Child rearing involving criticism and low empathy associated with Sz but only for those with genetic vulnerability

Original model too simple

Multiple genes influence onset of Sz


Stress can come in many forms


Vulnerability a result of early trauma

Support for effectiveness of combined treatment
Turkington et. al. said it is not possible to use combination treatment without accepting the interactionist approachCombination groups been proven to show less symptoms