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43 Cards in this Set
- Front
- Back
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Atropine-like side effects
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TCAs, low potency antipsychotics, 1st generation H1 blockers, amantadine
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Coronary vasospasm
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Cocaine, Sumatriptan, amphetamines, methamphetamines, ergotamines
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Cutaneous flushing
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VANC: vancomycin, adenosine, niacin (give aspirin to prevent), CCB (dihyropyridine)
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Dilated cardiomyopathy
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Doxorubicin, danunorubicin
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Torsades de pointes- Need to push Mg
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Class III (sotalol), class IA (quinidine), macrolides, chloroquine, mefloquin, methadone, HIV protease inhibitors, haloperidol, risperidone
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Agranulocytosis
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Clozapine, carbamazepine, colchicine, PTU, methimazole, dapsone
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Aplastic anemia
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Chloramphenicol, benzene, NSAIDs, PTU, methimazole
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Direct Coombs-positive hemolytic anemia
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Methyldopa (anti-hypertensive that is safe in pregnancy)
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Gray baby syndrome
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Chloramphenicol
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Hemolysis in G6PD deficiency
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Hemolysis IS PAIN: INH, Sulfonamides, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin. Also dapsone, napthalene, fava beans
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Megaloblastic anemia
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Phenytoin, Methotrexate, Sulfa drugs (having a blast with PMS)
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Thrombotic complications
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OCPs
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Thrombocytopenia
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Heparin, H2 blockers
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Cough
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ACEI (due to bradykinin)
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Pulmonary fibrosis
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Bleomycin, Amiodarone, Busulfan (it's hard to BLAB when you have pulmonary fibrosis)
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Acute cholestatic hepatitis
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Erythromycin
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Focal to massive hepatic necrosis
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Halothane, valproic acid, acetaminophen, Amanita phalloides
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Hepatitis
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INH
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Pseudomembranous colitis
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Clindamycin, ampicillin
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Adrenocortical insufficiency
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Glucocorticoid withdrawal (HPA suppression- tertiary)
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Hot flashes
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Tamoxifen, clomiphene
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Hypothyroidism
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Lithium, amiodarone
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Gynecomastia
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Some Drugs Create Awesome Knockers- Spironolactone, Digitalis, Cimetidine, Alcohol use, estrogens, Ketoconazole
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Gingival hyperplasia
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Phenytoin
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Gout
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Furosemide, thiazides
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Osteoporosis
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Corticosteroids, heparin
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Photosensitivity
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Sulfonamides, amiodarone, tetracyclines (SAT for a photo)
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Rash (SJS)
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Ethosuximide, lamotrigine, carbamazepine, phenobarbital, phenytoin, sulfa drugs, penicillin, allopurinol (seizures, sulfurs, cilins)
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SLE-like syndrome
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Sulfonamides, Hydralazine, INH, Procainamide, Phenytoin (SHIPP)
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Tendonitis, tendon rupture, and cartilage damage
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Fluoroquinolones
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Fanconi's syndrome
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Expired tetracycline, heavy metal exposure, wilson's disease (defect in PT reabsorption)
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Interstitial nephritis
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Methicillin, NSAIDs, furosemide
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Hemorrhagic cystitis
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Cyclophosphamide, ifosfamide (co-administer mesna)
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Cinchonism (dizziness, headache, tinnitus, GI)
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Quinidine, quinine
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Diabetes insipidis
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Lithium (add amiloride + HCTZ), demeclocycline
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Parkinson-like syndrome
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Haloperidol, chlorpromazine, reserpine, metoclopramide, MPTP
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Seizures
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Buproprion, imipenem/cilastatin, INH, enfluorane, benzo/alcohol withdrawal
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Tardive dyskinesia
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Antipsychotics (high potency/typical)
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Disulfiram-like reaction
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Metronidazole, certain cephalosporins, procarbazine, 1st generation sulfonylureas, disulfiram
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Nephrotoxicity/neurotoxicity
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Polymyxins
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Nephrotoxicity/ototoxicity
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Aminoglycosides, vancomycin, loop diuretics, cisplatin
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Inducers of P-450
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Barbiturates, Carbamazepine, Griseofulvin, Phenytoin, Quinidine, Rifampin, St. Johns wort, Chronic alcohol (eToh) use (BCG PQRST)
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Inhibitors of P450
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HIV protease inhibitors, Ketoconazole, Erythromycin, Grapefruit juice, Acute alcohol use, Sulfonamides, Isoniazid, Cimetidine, Amiodarone, TMP-SMX (Inhibit yourself from drinking a beer from a KEG because it makes you ACUTEly SICk)
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