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43 Cards in this Set
- Front
- Back
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Anti-muscarinic
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TCAs
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Cutaneous flushing
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Niacin- releases PGD2
Ca2+ channel blockers Adenosine Vancomycin |
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Torsades des pointes
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Class III antiarrythmic- Sotalol
Class IA- Quinine |
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Agranulocytosis
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Clozapine/Carbamazepin/Colchicine
Propylthioruacil/ Methimazole |
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Aplastic anemia
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Chloramphenicol
Benzene NSAIDs Propylthiouracil/ Methimazole |
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Direct Coombs-positive hemolytic anemia
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Methyldopa
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Hemolysis in G6PD-def
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Isoniazid
Sulfonmides Primaquine Aspirin Ibuprofen Nitrofurantoin (hemolysis IS PAIN) |
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Pulmonary fibrosis
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Bleomycin
Busulfan Amiodarone |
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Acute CHOLESTATIC hepatitis
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Macrolides
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HEPATIC NECROSIS
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Halothane
Valproic acid Acetaminophen Amanita phalloides |
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Hepatitis
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INH
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Pseudomembranous colitis
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Clindamycin. Ampicillin!
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Gynecomastia
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Spironolactone
Digitalis Cimetidine Alcohol Ketoconazole (Some Drugs Create Awesome Knockers) |
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Hot flashes
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Tamoxifen
Clomiphene- inhibits estrogen |
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Gingival hyperplasia
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Phenytoin
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Gout
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Furosemide, thiazides
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Osteoporosis
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Corticosteroids
Heparin************* |
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Photsensitivity
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Sulfonamides
Amiodarone Tetracycline (SAT for a photo) |
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SLE-like syndrome
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Hydralazine
Isoniazid Procainamide Phenytoin (it's not HIPP to have lupus) |
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Fanconi's syndrome
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Expired tetracycline
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Hemorrhagic cystitis
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Cyclophosphamide/ Ifosfamide- prevent with mesna
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Diabetes insipidus
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Lithium
Demeclocycline |
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Seizures
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Bupropion- NE, 5HT reuptake inhibitor
Imipenem/Cilastatin combo |
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Tardive dyskinesia
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Antipsychotics
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Disulfiram-like
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Metronidazole
Cephalosporins Procarbazine- chemotherapy First gen sulfonylureas |
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Nephrotoxicity/neurotoxicity
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Polymyxins
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Nephrotoxicity/ototoxicity
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Aminoglycosides
Loop diuretics Cisplatin |
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P450 Inducers
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Quinidine
Barbiturates Phenytoin/ Phenobarbitol Rifampin Griseofulin Carbamazepine St. John's wort (Queen Barb takes Phen-phen and Refuses Greasy Carb Shakes) |
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P450 Inhibitors
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Isoniazid
Sulfonamides Cimetidine Ketoconazole Erythromycin Grapefruit juice Ritonivir (Inhibitors Stop Cyber-Kids from Eating Grapefruit) |
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Sulfa drug examples
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Celecoxib
Furosemide Thiazides |
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Induced SER
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Alcohol
Barbiturates Phenytoin Rifampin |
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Reasons for dilated cardiomyopathy
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Alcohol abuse
Beriberi Cosackie B Cocaine Chagas Doxorubicin/Daunorubicin Peripartum |
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Hyper-PTH
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Phenothiazine @ D2, doesn't suppress
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Acute porphyria attack
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Phenobarbitol
Griseofulvin Phenytoin |
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Acute tubular necrosis
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Aminoglycosides
Contrast Cisplatin Ampho B Foscarnet |
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Intratubular obstruction
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Sulfonamides
MTX Acyclovir iv Triamterene |
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Renal interstitial nephritis
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Methicillin, NSAIDs
Cephalosporins Acetazolamide Allopurinol Sulfonamides Lithium Cyclosporin |
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Resistance mechanisms
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Aminoglycosides- modification- aceylation, adenylation, phosphorylation
Chloramphenicol- acetylation Macrolides- methylation ofRNA at binding site Tetracycline- decreased uptake or transport out Sulfonamides- altered enzyme, decreaed uptake, or increased PABA Quinolones- altered gyrase or reduced uptake |
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Hypothyroidism
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Amiodarone
Lithium |
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Drug-induced cholestasis
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OCP
Steroids Chlorpromazine |
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Drug-induced granulomatosis
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Methldopa
Hydralazine Quinidine |
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Drugs that can cause seizures
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Bupropion
INH Imipenam |
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Hydroxychloroquine
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For seronegative RA, SLE
Permanent retinal damage! |
