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46 Cards in this Set
- Front
- Back
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atropine-like S/E's
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- TCA's
- low potency typical neuroleptics - 1st gen antihistamines - amantadine (antiviral/antiparkinsonian) |
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coronary vasospasm
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- cocaine, amphets, meth
- sumatriptan - ergotamines (HA's) |
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cutaneous flushing
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"VANC"
- Vancomycin (slow admin, prophlax w/antihist) - Adenosine - Niacin (tx w/aspirin) - Ca2+ chan blockers |
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dilated cardiomyopathy
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- doxorubicin
- daunorubicin |
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torsades de pointes
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- class III (sotalol) antiarryth
- class IA (quinidine) antiarryth - cisapride - macrolides - haloperidol/respiradone - protease inhibitors - methadone - chloriquine/methlaquine |
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agranulocytosis
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- clozapine
- carbamazepine - colchicine - propylthiouracil (PTU), methimazole (thyroid) - dapsone |
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aplastic anemia
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- chloramphenicol
- benzene - NSAIDs - PTU, methimazole |
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direct coombs-positive hemolytic anemia
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methyldopa
(anti-HTN, safe in preg) |
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gray baby syndrome
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chloramphenicol
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hemolysis in G6PD-deficient pts
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"hemolysis IS PAIN"
- Isoniazid (INH) - Sulfonamids - Primaquine - Aspirin (high dose) - Ibuprofen - Nitrofurantoin - (& dapsone, napthelene, fava beans) |
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megaloblastic anemia
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- Phenytoin
- Methotrexate - Sulfa drugs |
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thrombotic complications (DVT's, PE's)
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OCP's (estrogens, progestins)
(esp in smoker & >35) |
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who's at an increased risk of stroke w/OCP's?
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pts w/migraine w/aura
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cough
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ACE-I's (but NOT ARB's!)
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cough & angioedema
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ACE-I's (but NOT ARB's!)
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pulmonary fibrosis
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- bleomycin
- amniodarone - busulfan - nitrofurantoin |
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acute cholestatic hepatitis
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erythromycin estolate
(not macrolides in general) |
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focal to massive hepatic necrosis
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- halothane
- valproic acid - acetaminophen (>4g/d) - Amanita phalloides |
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hepatitis
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INH
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pseudomembranous colitis
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any antibiotics (clinda, ampicillin...)
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adrenocortical insufficiency
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abrupt glucocorticoid withdrawal
(HPA suppression) |
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gynecomastia
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"Some Drugs Create AwesomE Knockers"
- Spironolactone - Digitalis - Cimetidine - Alcohol (chronic) - Estrogen - Ketoconazole (- & marijuana) |
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hot flashes
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SERM's
- tamoxifen - clomiphene |
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hypothyroidism
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- lithium
- amiodarone |
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gingival hyperplasia
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phenytoin
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gout
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- furosemide (loop)
- thiazides |
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osteoporosis
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- corticosteroids
- heparin |
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photosensitivity
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"SAT for a photo"
- Sulfonamides - Amiodarone - Tetracycline |
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Rash (Stevens-Johnson syndrome)
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"Seizures, sulfa's & 'cillins..." + allopurinol
- ethosuximide - lamotrigine - carbamazepine - phenobarbital - phenytoin - sulfa drugs - penicillin - allopurinol |
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SLE-like syndrome
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"SHIPP"
- Sulfonamides - Hydralazine - INH - Procainamide - Phenytoin (have anti-histone antibodies) |
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tendonitis, tendon rupture & cartilage damage (kids)
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fluoroquinolones
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Fanconi's syndrome
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- expired tetracycline
- heavy metal exposure - wilson's dz (defect of prox tubule reabsorp→ spill a ton of stuff in your urine) |
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interstitial nephritis
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- furosemide (loop)
- methicillin - NSAIDs ("F My Nephrons") |
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hemorrhagic cystitis
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- cyclophosphamide
- ifosfamide |
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prevent hemorrhagic cystitis d/t cyclophosphamide & ifosamide by:
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coadmin w/ mesna
(binds to toxic metabolites) |
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cinchonism
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quinidine/quinine
(cinchonism = dizzy, HA, tinnitis, nausea) (+sweating & hypervent = chronic salicylate toxicity) |
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nephrogenic diabetes insipidus
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- lithium
- demeclocycline |
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tx nephrogenic diabetes insipidus d/t Lithium w/...
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HCTZ + amiloride
(amiloride = K+ sparing diuretic) |
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parkinson-like syndrome
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- halperidol
- chlorpromazine - reserpine - metoclopramide (anti-emetic) - MPTP (illegal dimerol) (reversible) |
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seizures
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- buproprion (anti-smoking)
- imipenem/cilastatin - isoniazid - enflurane |
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tardive dyskinesia
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antipsychotics
(high potency typicals) |
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disulfiram-like reaction
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- metronidazole
- some cephalosporins - procarbazine - 1st gen sulfonylureas |
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nephrotoxicity / neurotoxicity
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polymyxins
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nephrotoxicity / ototoxicity
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- AG's (gentamicin)
- vanc - loop diuretics (furosemide) - cisplatin (loop + AG/salicylate/cisplatin = ototoxicity on world Q) |
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P450 inducers
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"BCG PQRS"
- Barbs - Carbamazepine / Chronic alcohol - Griseofulvin - Phenytoin - Quinidine - Rifampin - St. John's wort |
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P450 inhibitors
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"CAKE IS Great"
- Cimetidine - Acute Alcohol - Ketoconazole - Erythromycin - Isoniazid - Sulfonamides - Grapefruit |
