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46 Cards in this Set

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atropine-like S/E's
- TCA's
- low potency typical neuroleptics
- 1st gen antihistamines
- amantadine (antiviral/antiparkinsonian)
coronary vasospasm
- cocaine, amphets, meth
- sumatriptan
- ergotamines (HA's)
cutaneous flushing
"VANC"
- Vancomycin (slow admin, prophlax w/antihist)
- Adenosine
- Niacin (tx w/aspirin)
- Ca2+ chan blockers
dilated cardiomyopathy
- doxorubicin
- daunorubicin
torsades de pointes
- class III (sotalol) antiarryth
- class IA (quinidine) antiarryth
- cisapride
- macrolides
- haloperidol/respiradone
- protease inhibitors
- methadone
- chloriquine/methlaquine
agranulocytosis
- clozapine
- carbamazepine
- colchicine
- propylthiouracil (PTU), methimazole (thyroid)
- dapsone
aplastic anemia
- chloramphenicol
- benzene
- NSAIDs
- PTU, methimazole
direct coombs-positive hemolytic anemia
methyldopa
(anti-HTN, safe in preg)
gray baby syndrome
chloramphenicol
hemolysis in G6PD-deficient pts
"hemolysis IS PAIN"
- Isoniazid (INH)
- Sulfonamids
- Primaquine
- Aspirin (high dose)
- Ibuprofen
- Nitrofurantoin
- (& dapsone, napthelene, fava beans)
megaloblastic anemia
- Phenytoin
- Methotrexate
- Sulfa drugs
thrombotic complications (DVT's, PE's)
OCP's (estrogens, progestins)
(esp in smoker & >35)
who's at an increased risk of stroke w/OCP's?
pts w/migraine w/aura
cough
ACE-I's (but NOT ARB's!)
cough & angioedema
ACE-I's (but NOT ARB's!)
pulmonary fibrosis
- bleomycin
- amniodarone
- busulfan
- nitrofurantoin
acute cholestatic hepatitis
erythromycin estolate
(not macrolides in general)
focal to massive hepatic necrosis
- halothane
- valproic acid
- acetaminophen (>4g/d)
- Amanita phalloides
hepatitis
INH
pseudomembranous colitis
any antibiotics (clinda, ampicillin...)
adrenocortical insufficiency
abrupt glucocorticoid withdrawal
(HPA suppression)
gynecomastia
"Some Drugs Create AwesomE Knockers"
- Spironolactone
- Digitalis
- Cimetidine
- Alcohol (chronic)
- Estrogen
- Ketoconazole
(- & marijuana)
hot flashes
SERM's
- tamoxifen
- clomiphene
hypothyroidism
- lithium
- amiodarone
gingival hyperplasia
phenytoin
gout
- furosemide (loop)
- thiazides
osteoporosis
- corticosteroids
- heparin
photosensitivity
"SAT for a photo"
- Sulfonamides
- Amiodarone
- Tetracycline
Rash (Stevens-Johnson syndrome)
"Seizures, sulfa's & 'cillins..." + allopurinol
- ethosuximide
- lamotrigine
- carbamazepine
- phenobarbital
- phenytoin
- sulfa drugs
- penicillin
- allopurinol
SLE-like syndrome
"SHIPP"
- Sulfonamides
- Hydralazine
- INH
- Procainamide
- Phenytoin

(have anti-histone antibodies)
tendonitis, tendon rupture & cartilage damage (kids)
fluoroquinolones
Fanconi's syndrome
- expired tetracycline
- heavy metal exposure
- wilson's dz

(defect of prox tubule reabsorp→ spill a ton of stuff in your urine)
interstitial nephritis
- furosemide (loop)
- methicillin
- NSAIDs
("F My Nephrons")
hemorrhagic cystitis
- cyclophosphamide
- ifosfamide
prevent hemorrhagic cystitis d/t cyclophosphamide & ifosamide by:
coadmin w/ mesna
(binds to toxic metabolites)
cinchonism
quinidine/quinine
(cinchonism = dizzy, HA, tinnitis, nausea)
(+sweating & hypervent = chronic salicylate toxicity)
nephrogenic diabetes insipidus
- lithium
- demeclocycline
tx nephrogenic diabetes insipidus d/t Lithium w/...
HCTZ + amiloride

(amiloride = K+ sparing diuretic)
parkinson-like syndrome
- halperidol
- chlorpromazine
- reserpine
- metoclopramide (anti-emetic)
- MPTP (illegal dimerol)

(reversible)
seizures
- buproprion (anti-smoking)
- imipenem/cilastatin
- isoniazid
- enflurane
tardive dyskinesia
antipsychotics
(high potency typicals)
disulfiram-like reaction
- metronidazole
- some cephalosporins
- procarbazine
- 1st gen sulfonylureas
nephrotoxicity / neurotoxicity
polymyxins
nephrotoxicity / ototoxicity
- AG's (gentamicin)
- vanc
- loop diuretics (furosemide)
- cisplatin

(loop + AG/salicylate/cisplatin = ototoxicity on world Q)
P450 inducers
"BCG PQRS"
- Barbs
- Carbamazepine / Chronic alcohol
- Griseofulvin
- Phenytoin
- Quinidine
- Rifampin
- St. John's wort
P450 inhibitors
"CAKE IS Great"
- Cimetidine
- Acute Alcohol
- Ketoconazole
- Erythromycin
- Isoniazid
- Sulfonamides
- Grapefruit