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23 Cards in this Set
- Front
- Back
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What SE attributed to calcium channel blockers can show up in 3 mon ths or so after starting drug
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minor skin reactions...rash, itching, photosensitivity.
Now preliminary evidence suggests that calcium blockers can cause a delayed eczema rash...usually about 3 months after starting the drug. There are also reports of other serious skin reactions... erythema multiforme, exfoliative dermatitis, toxic erythema, etc. |
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Inhalation with a dry powder inhaler should be
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Forceful
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Evamist is
strength dose |
Estradiol spray
21mcg per spray 1-3 sprays a day on forearms |
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amoxicillin dose for resistant pneumococcal infection
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80-90mg/kg up to 3 Gm a day, 4gm if over 44kg
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generic name of TEkturna
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Aliskiren
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What 2 triptans are the longest acting
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Frovia and Amerge
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Which drug can cause restlessness and insomnia ?
Serroquel- Abilify- Zyprexa |
Abilify
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What is Ryzolt
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Extended release tramadol- peaks quicker than Ultram ER
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Black Box warning for quinolones ?
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Tendon rupture
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where does tendon rupture with quin olones occur most frequently
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Achilles Tendon- although it can occur in shpulders arm or hands also
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dutasteride is
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Avodart
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What is an agonist
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An agonist is a compound that binds to a receptor and produces the biologic response
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A partial agonist
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produces the biologic response but cannot produce 100% of the response even at high doses
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Efficacy is
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the maximal response that a drug can produce
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Potency is
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a measure of the dose that is required to produce a response
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ED50 is
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the dose required to get 50% of the response
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Therapeutic index is
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a measure of drug safety. Drugs with high therapeutic index are safer than drugs with a lower one
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Therapeutic index =
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LD50 / ED50
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Competitive antagonists
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attach to the same receptor sites as the agonist.
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Non competitive antagonists
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irrersinly bind to the same receptor or block the response in some other way
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First pass metabolism is
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drugs absorbed in the GI tract first pass through the liver and can be metabolized before reaching the general circulatiuon
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Samsca is generically
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tolvaptan
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Samsca is used for
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hyponatremia
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