Drug Induced Pulmonary Disease

Front 1

This drug induced pulmonary disease is induced by central nervous system depression or respiratory neuromuscular blockade

Back 1

drug-induced apnea

Front 2

drug induced apnea is more commonly seen in what population?

Back 2

elderly and chronically debilitated

Front 3

concurrent use of what agents together are likely to lead to greater respiratory depression?

Back 3

cyp3A4 inhibitors and benzodiazepines

Front 4

narcotic analgesics
barbituates
benzodiazepines
and corticosteroids induce what

Back 4

apnea

Front 5

drug induced bronchospasmsis almost exclusively a problem for what type of patients

Back 5

patients with pre-existing broncial hyperreactivity

Front 6

penicillins
suflfonamides
serum
cephalosporins
papain
L-asparaginase
produce what type of bronchospasm

Back 6

anaphylaxis

Front 7

bisulfte, smoke, and N-acetylcystein produce what type of bronchospasm

Back 7

direct airway irritation

Front 8

aspirin/nsaids produce what type of bronchospasm

Back 8

cyclooxygenase inhibition

Front 9

iodinated-radiocontrast media produce what type of bronchospasm

Back 9

anaphylactoid mast-cell degranulation

Front 10

alpha adrenergic recepter blockers produce what type of bronchospasm

Back 10

pharmacologic effects

Front 11

an increase in the prevalence of asthma and COPD is present with an increase use of what drug

Back 11

apap

Front 12

what is the aspirin triad

Back 12

aspirin exposure
nasal polyps
severe asthma exacerbated by aspirin

Front 13

classic decription of aspirin intolerant includes what 3 things

Back 13

aspirin triad
nasal polyps
aspirin intolerance

Front 14

what is the treatment for drug induced apnea

Back 14

ventilation
anticholinesterase

Front 15

watermelon

Back 15

2 count midori
2 count vodka
balance pineapple juice
tope with grenadine
serve in a tall glass with a flag

Front 16

how can you treat someone who is asa intolerant

Back 16

desensitization
avoidance

Front 17

how long after d/c of asa desensitization do patients become asa intolerant again

Back 17

7 days

Front 18

up to 80% of asa sensitive patients are also allergic to what dye?

Back 18

yellow azo dye tartrazine (yellow #5)

Front 19

beta blocker are hazardous to patients with what disease?

Back 19

asthma

Front 20

anaphylactic or anaphylactoid reactions to sulfites in this population is rare

Back 20

nonasthmatics

Front 21

sulfite sensitive patients can be protected by pretreatment with what drugs

Back 21

cromolyn
anticholinergics
cyanocobalamin

Front 22

These patients have an increased risk of latex allergy

Back 22

patients with spina bifida

Front 23

Cough due to this agent is unresponsive to bronchodialators and antitussive agents

Back 23

ACEI cough

Front 24

excessive IV fluids
blood/plasma transfusions
and corticosteroids cause this type of pulmonary edema

Back 24

cardiogenic pulmonary edema

Front 25

heroin cause this type of pulmonary edema

Back 25

noncardiogenic pulmonary edema

Front 26

narcotic induced pulmonary edema is treated with what

Back 26

naloxone
O2
ventilatory support

Front 27

these drugs cause pulmonary eosinophilia

Back 27

nitrofurantoin
para-aminosalicylic acid

Front 28

Bleomycin can cause two types of drug-induced pulmonary disease, what are they

Back 28

fibrosis and edema

Front 29

these agents produce pulmonary fibrosis

Back 29

antineoplastics
bleomycin
mitomycin
antimetabolites
amiodarone

Front 30

early withdrawal and administration of this drug improve the outcome of mitomycin induced pulmonary fibrosis

Back 30

corticosteroids

Front 31

amiodarone can cause pulmonary fibrosis when used for what type of arrythmias?

Back 31

supraventricular and ventricular

Front 32

by what process can amiodarone damage the lung

Back 32

cytotix process or immunologic reactions