Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
136 Cards in this Set
- Front
- Back
|
citalopram
|
celexa
SSRI |
|
|
escitalopram
|
lexapro
ssri |
|
|
fluoxetine
|
prozc
ssri |
|
|
fluvoxamine
|
luvox
ssri |
|
|
paroxetine
|
paxil
ssri |
|
|
sertraline
|
zoloft
ssri |
|
|
nefazodone
|
(generic only)
5-th2 antagonist (anti-depressant) |
|
|
trazodone
|
dessyrel
and generic anti-depr |
|
|
bupropion
|
wellbutrin
|
|
|
mirtrazapine
|
remeron
anti depr (other) |
|
|
venlafaxine
|
effexor
anti-depr (other) |
|
|
duloxetine
|
cymbalta
anti-depr (other) |
|
|
trazodone
|
desyrel
5ht2 antagonist (antidepr) |
|
|
nefazodone
|
serzone
5ht2 antagonist (antidepr) |
|
|
reboxetine
|
?
norepinephrine reuptake inhibitors anti-depr |
|
|
atomoxetine
|
strattera
norepinephrine reuptake inhibitors anti depr |
|
|
amitriptyline
|
elavil
TCA |
|
|
clomipramine
|
anafranil
TCA |
|
|
despipramine
|
norpramine
TCA |
|
|
doxepin
|
sinequan
TCA |
|
|
imipramine
|
tofranil
TCA |
|
|
nortriptyline
|
aventyl, pamelor
TCA |
|
|
protriptyline
|
vivactil
tca |
|
|
trimipramine maleate
|
surmontil
tca |
|
|
amoxapine
|
ascendin
tca |
|
|
maprotiline
|
ludiomil
TCA |
|
|
phenelzine
|
nardil
MAOI |
|
|
selegiline
|
eldepryl,
carbex, emsam MAOI |
|
|
tranylcypromine
|
parnate
MAOI |
|
|
isocarboxazid
|
marplan
MAOI |
|
|
aripizole
|
abilify
antipsychotic |
|
|
chlorpromazine
|
thorazine
antipsychotic |
|
|
clozapine
|
clozaril
anit psychotic |
|
|
droperidol
|
inapsine
antipsychotic |
|
|
fluphenazine
|
prolixin
anti psychotic |
|
|
haloperidol
|
haldol
antipsychotic |
|
|
loxapine
|
loxitane
anti psychotic |
|
|
mesoridazine
|
serentil
anti psychotic |
|
|
molindone
|
moban
antipsychotic |
|
|
olanzapine
|
zyprexa
antipsychotic |
|
|
perphenazine
|
trilafon
anti psychotic |
|
|
pimozide
|
orap
antipsychotic |
|
|
quetiapine
|
seroquel
antipsychotic |
|
|
risperidone
|
risperdal
antipsychotic |
|
|
thioridzine
|
mellaril
antipsychotic |
|
|
thiothixene
|
navane
antipsychotic |
|
|
trifluoperazine
|
stelazine
antipsychotic |
|
|
ziprasidone
|
geodon
antipsychotic |
|
|
benztropine
|
cogentin
antiparkinsonian |
|
|
biperiden
|
akineton
antiparkinsonian |
|
|
diphenhydramine
|
benadryl
antiparkinsonian |
|
|
procyclidine
|
kemadrin
antiparkinsonian |
|
|
trihexyphenidyl
|
artane
antiparkinsonian |
|
|
amantadine
|
symmetrel
antiparkinsonian (**primarily dopaminergic) |
|
|
lithium
|
eskalith, lithobid
mood stabilizer |
|
|
carbamazepine
|
tegretol
mood stabilizer |
|
|
valproic acid
valproate sodium divalproex sodium |
depakene
depacon depakote mood stabilizer |
|
|
lamotrigine
|
lamictal
mood stabilizer |
|
|
gabapentin
|
neurotnin
mood stabilizer |
|
|
oxcarbazepine
|
trileptal
mood stabilizer |
|
|
topiramate
|
topamax
mood stabilizer |
|
|
tiagabine
|
gabitril
mood stabilizer |
|
|
chlordiazepoxide
|
librium
anxiety / benzo |
|
|
clorazepate
|
trnzene
anxiety / benzo |
|
|
diazepam
|
valium
anxiety / benzo |
|
|
clonazepam
|
klonopin
anxiety / benzo |
|
|
lorazepam
|
ativan
anxiety /benzo |
|
|
oxazepam
|
serx
anxiety / benzo |
|
|
alprazolam
|
xanax
anxiety / benzo |
|
|
propanolol
|
inderal
beta blocker (anti anx) |
|
|
amobarbital
|
amytal
barbituate / anti anx |
|
|
butabarbital
|
butisol
barbituate / anti anx |
|
|
mephobarbital
|
mebaral
barbituate / anti anx |
|
|
pentobarbital
|
nembutal
barbituate / anti anx |
|
|
phenobarbital
|
vrious agents
barbituate / anti anx |
|
|
meprobamate
|
miltown
carbamate / anti - anx/ sedative |
|
|
clonidine
|
catapres, duraclon
nordrenergic anti anx/sedative |
|
|
propanolol
|
inderal
noradrenergic anti anx/sedative |
|
|
hydroxyzine hcl,
hydroxyzine pamoate |
atarax, vistaril
antihistamine anti anx/sedative |
|
|
buspirone
|
buspar
"other" anti anx/sedative |
|
|
flurazepam
|
dalmane
benzo/hypnotic |
|
|
temazepam
|
restoril
benzo/hypnotic |
|
|
quazepam
|
doral
benzo/hypnotic |
|
|
triazolam
|
halcion
benzo/hypnotic |
|
|
estazolam
|
proSom
benzo/hypnotic |
|
|
butabarbital sodium
|
butisol sodium
bartbituate hypnotic |
|
|
pentobarbital
|
various
barbituate hypnotic |
|
|
secobrbital
|
seconal
barbituate hypnotic |
|
|
secobarbital and amobarbital
|
tuinal
barbituate hypnotic |
|
|
zolpidem
|
ambien
"other" hypnotic |
|
|
zaleplon
|
sonata
other hypnotic |
|
|
eszopiclone
|
lunesta
other hypnotic |
|
|
remelteon
|
rozerem
other hypnotic |
|
|
chloral hydrate
|
noctec
other hypnotic |
|
|
name the SNRIs
|
cymbalta and effexor
|
|
|
what should you consider with someone with brain injury
|
can have drastic effects b/c the blood/brain barrier is more permeable
|
|
|
the peripheral nervous system innervates ____________
|
the organs and tissues
|
|
|
what is a psychotropic drug?
|
any drug used to treat psychological sx
|
|
|
most of the the side effects you see are where?
|
in the peripheral nervous system
|
|
|
where do most Rx effects occur?
|
in the midbrain region, the midbrain is where EMOTIONS are
|
|
|
what is the brain stem responsible for?
|
respiration
|
|
|
what is the action of an SSRI
|
it's a selective serotonin reuptake inhibitor, therefore: reuptake is inhibited... so it INCREASES the bio-availabilitiy of serotonin
|
|
|
how is dopamine inhibited? what happens then?
|
dopamine is BLOCKED from the receptors.. the body then increases the number of receptors, which is what causes tardive dyskinesia
|
|
|
what is EPS
|
extrapyramidal SE in the pyramidal track, causes MOVEMENT disorders
|
|
|
cocaine is sympathomimetic so it....
|
imitates neurotransmitters,so do amphetamines
|
|
|
which method of admistration of Rx is the most irreversible
|
IV intravenous
|
|
|
what is a bolus for?
|
when giving IM drug, it may be too caustic, so in a bolus body can handle it easier
|
|
|
what are neuroleptics
|
anti psychotics
|
|
|
what is the px with neuroleptics?
|
always feel drugged, so daily struggle for compliance
|
|
|
what is the px with neuroleptics?
|
always feel drugged, so daily struggle for compliance
|
|
|
what are depot agents for
|
used to deal with compliance, oily substrate to make it absorb slowly over time, prolixin and haldol
|
|
|
whats an agonist
|
it occupies the site and exerts a similar effect on the body. most Rx are AGONISTS
|
|
|
what does an antagonist do
|
it fully occupies the site, so if you took the drug it won't make a difference (eg this is how methodone works, heroin can't have effect b/c methodone is occupying site)
|
|
|
what is a drug interaction
|
when taking multiple drugs, liver can break it down into 2 active compounds, when many drugs, have multiple compounds and many new/possible toxic molecules
|
|
|
define biotransformation
|
this is what happens in the liver, and then its eliminated, either thru exhalation, urine, feces, sweat
|
|
|
anything that interferes with absoption in the bloodstream interferes with what of a drug?
|
the bioavailabililty
|
|
|
what is the major contributing factor to bioavailability?
|
the efficiency of the liver, more efficient =processed faster; elderly = slow (give less often);
children/babies = very fast (so lower doses and more OFTEN) |
|
|
what are the issues with Rx and the elderly
|
less body mass, less fat, less muscle
most meds are lipid soluble (stored in fat); each drug distributes some store to fatty tissues, only what is not stored is used, so in elderly, less is stored (so it's hanging around, I THINK) |
|
|
define therapeutic half-life
|
how long it is to get to 1/2 of the therapeutic level
|
|
|
define metabolic half-life
|
when 1/2 of the amount is in the blood
|
|
|
what is tissue saturation
|
when the drug is at a therapeutic level, you are at a "steady state" and therefore generally have less side effects
|
|
|
define onset of action
|
how long it takes to see desired effects
|
|
|
define hangover effect
|
duration of the action/effect
|
|
|
why do side effects happen
|
when the drug is going to a non-targeted site
|
|
|
tolerance is....
|
the body is always trying to compensate, so they transform the drugs FASTER, more efficiently, so you need MORE of the drug to get the same effect (liver is like pacman and will multiple the pacmans to keep up)
|
|
|
alcohol depresses cellular function, so what happens when not drinking
|
b.c alcohol slows it down, when not drinking, cells will try to speed up extra b/c they COMPENSATE, so the cell is HYPERFUNCTIONING = withdrawal... get a fine hand tremor b/c cells are over functioning, any CNS depressant (tranquilizer) will stop it
|
|
|
what happens in withdrawal from a depressant?
|
w/d is EXCITATION
|
|
|
what happens in withdrawal of a stimulant
|
it's DEPRESSING (crash)
|
|
|
define rebound effects
|
rebound is when you stop taking it, e.g sleeping pill, you can't sleep at all
|
|
|
define cummulative effects
|
get more drug in your body than you need, can lead to toxicity
|
|
|
define drug synergism
|
when you take one drug, it enhances action of another (eg if give a thyroid pill with antidepressant, it will increase the bioavailability to the other)
|
|
|
augmentation is taking advantage of what?
|
drug synergism (giving one enhances the bioavailabiliity to the other)
|
|
|
what happens when you have an allergic reaction to a drug
|
once you have allergic reaction it gets worse the next time, eg with penicillin 1st time = hives, 2nd time you can die
|
|
|
allergic reaction leads to ...
|
hypersensitivity (I guess)
|
|
|
compliance wise, what can you expect for a person taking drugs, 1x, 2x, 3x and 4 x /d
|
more you have to take it the less likely to take it, so
1x qd 80% compliance 2x 60% 3x 40% 4x 20% |
|
|
what are many psychotropic drugs better for a 1x day regimen?
|
most are fat soluble, so once they get into your system, you only need to take once a day
|
