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36 Cards in this Set

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Angiotensin-converting enzyme

Hypertension;



Actions: dilatation of the arterial and venous systems occur through the suppression of renin-angiotensin I to angiotensin II conversion

Captopril, Lisinopril, Enalapril

Angiotensin receptor blockers (ARBs)

Hypertension;



Actions: dilatation of the arterial and venous systems occur through the blocking of the angiotensin II receptors

Losartan, Valsartan, Irbesartan

Antacids

Gastritis, Peptic Ulcer, Hiatal Hernia, reflux esophagitis;



They contains magnesium, aluminium, calcium, and a combination of these compounds. They slow down the rate of gastric emptying and neutralise gastric acidity

Aluminium Carbonate, Calcium Carbonate, Maalox, Mylanta

Anticoagulants

MI, pulmonary embolus, DVT, disseminated intravascular clotting syndrome (DIC), atrial fibrillation

Warfarin Sodium, Heparin, Enoxaparin, Dabigatran

Anticonvulsants

Prevent seizures

Phenytoin, Diazepam, Gabapentin, Valproic acid

Antidepressants

Depression, nocturnal enuresis (in children)



Blocks the breakdown or inhibits the reuptake of epinephrine, norepinephrine, serotonin, and dopamine which increases their actions in the nerve cells

Sertraline, Amitriptyline, Bupropion, Fluoxetine

Antidiabetic medications

Insulins- lower blood sugar, potassium, phosphate



Oral hypoglycemic agents- stimulate the beta cells of pancreas to release insulin

Antidiarrheals

Diarrhoea



Decrease water content of stool, some slow down GI peristalsis

Bismuth Subgallate, Kaolin and Pectin Mixtures, Lomotil

Antidysrhythmics

Atrial and ventricular arrhythmias, hypertension, angina

Digoxin, Procainamide, Quinidine, Acdbutolol, Bretylium, Verapamil

Antifungals

Fungal infections



Decreases sodium, potassium and nutrients in the cell and increases cell permeability

Nystatin, Amphotericin B

Antihistamines

Allergies, pruritus, rhinitis



Blocks histamine

Diphenhydramine Hydrochloride, Chlorpheniramine Maleate,

Antiinfectives

Infection

Penicillin, Cephalexin, Gentamicin, Azithromycin, Erythromycin, Ciprofloxacin, Tetracycline

Antineoplastics

Tumours, lymphoma, leukaemia, Hodgkin's Disease



Interfere with DNA, RNA synthesis or by affecting the hormones associated with tumour growth

Fluorouracil, Cisplatin, Taxol, Doxorubicin, Mitomycin

Antiparkinson agents

Parkinson's Disease



Blocks acetylcholine or activates dopamine receptors

Levodopa, Entacapone, Selegiline, Ropinirole

Antipsychotic and neuroleptic agents

Schizophrenia, mania, paranoia, anxiety



Block dopamine receptors in the brain

Haloperidol, chlorpromazine, Olanzapine, Risperidone, Aripirazole, Quetiapine

Anti tuberular

Pulmonary tuberculosis



Decreases the replication of the offending bacillus through the inhibition of RNA or DNA

Isoniazid, Rifabutin, Rifampin

Antitussives and expectorants

(Non-productive cough) bronchitis, TB, pneumonia, cystic fibrosis and COPD

Guaifenasin, Codeine, Dextromethorphen

Antivirals

Infections (HIV infections, herpes

Acyclovir, Cidofovir, Lamivudine

Barbiturates

Epilepsy, sedation, insomnia, anaesthesia, cholestasis

Phenobarbital, Secobarbital

Benziodiazepines

Anxiety, acute alcohol withdrawal, pre-operative relaxation



Decreases anxiety by potentiating g-aminobutyric acid and other CNS inhibitory transmitters

(Suffix= Pam)


Diazepam, Clonazepam, Lorazapam, Oxazepam

Beta-Adrenergic Blockers

Hypertension, angina prophylaxis, ventricular dysrhythmia



Block the stimulation of beta receptors in the cardiac smooth muscle, lowering blood pressure and may reduce heart rate

(Suffix= olol)


Metoprolol, Propranorol, Bisoprolol

Bronchodilators

Asthma, bronchospasm, COPD, emphysema, Cheyne-Stokes respirations

Albuterol, Aminophylline, Levalbuterol

Calcium Channel Blockers

Angina, hypertension, dysrhythmia



Inhibit calcium ions across the cell membrane of cardiac and vascular smooth muscle to relax them, dilating coronary arteries, slows SA/AV node conduction, and dilating peripheral arteries

Cardiac Glycosides

CHF, Tachycardia



Cardiac output and cardiac contractility are enhanced by making more calcium available

Digitoxin, Dixogin

Cholinergic Blockers

Preventing surgical secretions, decreasing motility of urinary, biliary and GI tracts, reverses neuromuscular blockades



Blocks the autonomic nervous systems and system's acetylcholine

Atropine, Scopolamine, Belladonna

Corticosteroids

Two types:


Glucocorticoids: decrease inflammation; some are used for adrenal insufficiency, allergies and cerebral edema



Increases capillary permeability and decreases inflammation



Mineralocorticoids: adrenal insufficiency



Increase potassium and hydrogen excretion in the distal tubule by increasing the resorption of sodium

Cortisone, dexamethasone, hydrocortisone

Diuretics

Hypertension and Edema with CHF



Work in kidney by altering electrolyte balance and increase the excretion of water as a result

Furosemide, hydrochlorothiazide, spironolactone

Histamine H2 antagonists

Gastric and duodenal ulcers, gastroesophageal reflux disease



Inhibits histamine in the stomach, thereby inhibiting the secretion of gastric acid secretion

Cimetidine, Ranitidine

Immunosuppressents

Preventing organ transplant rejection



Inhibits lymphocytes

Cyclosporine, azathiomide

Laxatives

Constipation



Work by increasing water retention, speeding up intestinal contractions, or reducing the surface tension

Psyllium, Docusate Sodium, Magnesium Hydroxide, Mineral Oil, Bisacodyl

Nitrates

Angina, Calcium channel blockers and beta blockers can be used for hypertension and dysrhythmias



Dilate coronary arteries, decrease preload and afterload

Nitroglycerin, isosorbide dinitrate, isosorbide monotirate

Nonsteroidal antiinflammatories (NSAIDs)

Mild to moderate pain, arthritis, dysmenorrhoea



Decreases prostaglandin synthesis

Ibuprofen, Naproxen, Diclofenac

Opioid Analgesic

Moderate-severe pain



Depression of the pain impulse transmission at the level of the spinal cord

Codeine, Fentanyl, Morphine, Oxycodone, Hydrocodone, Hydromorphone

Salicylates

Mild-moderate pain, inflammation (Arthritis) fever, thromboemolitic disorders



Antipyretic (inhibits the heat regulation centre in the hypothalamus, anti-antiinflammatory (inhibits prostaglandin) Analgesic (inhibits prostaglandin)

Aspirin, Salsalate

Thrombolytics

Pulmonary emboli, DVT, arterial thrombosis, with or after MI, arteriovenous cannula occlusion

Streptokinase, urokinase

Thyroid Medications

Thyroid Replacement



Increases metabolism, cardiac output, blood volume, oxygen consumption, and respiratory rate

Thyroid, Levothyroxine