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19 Cards in this Set

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Name 3 lipid-lowering agents?
bile acid sequestrants
HMG-CoA reductase inhibitors
miscellaneous
Name 3 bile acid sequestrants?
cholestyramine
colesevelam
colestipol
Name 6 HMG-CoA reductase inhibitors?
atorvastatin
fluvastatin
lovastatin
pravastatin
rosuvastatin
simvastatin
Name 5 miscellaneous lipid-lowering agents?
ezetimibe
fenofibrate
gemfibrozil
niacin
niacinamide
Lipid-lowering agents are used as a part of a total plan including diet and exercise to reduce blood lipids in an effort to reduce morbidity and mortality of _________ cardiovascular disease and its _______.
atherosclerotic
sequelae
Vytorin or
generic name ezetimibe/simvastatin is a
new (July 2006) combination medication on the market that doctors are using in place of?
Lipitor (newspaper)
manufactured for
Merck/Schering-Plough Pharm.
Which group of lipid-lowering agents inhibit an enzyme involved in cholesterol synthesis?
HMG-CoA reductase inhibitors
Which group of lipid-lowering agents bind cholesterol in the GI tract?
bile acid sequestrants
The miscellaneous lipid-lowering agents act by other mechanisms and are separated in individual monographs.
okay
Contraindications?
hypersensitivity
Precautions?
Safety in pregnancy, lactation, and children not established. See individual drugs. Dietary therapy should be given a ___ to ____ month trial before drug therapy is initiated.
2-3
Interactions?
Bile acid sequestrants (cholestyramine and colestipol) may bind ____-____ vitamins (A,D,E, and K)
and other concurrently administered drugs in the GI tract. The risk of myopathy from ______ reductase inhibitors is increased by niacin, erythromycin, gemfibrozil, and cyclosporine.
lipid-soluble
When assessing for use of lipid-lowering agents, obtain a diet history, especially in regard to ____ and ____ consumption.
fat
alcohol
When assessing for use of lipid-lowering agents, lab tests that should be considered before initiating and periodically throughout therapy are?
serum cholesterol levels
triglyceride levels

(medication should be discontinued if paradoxical increase in cholesterol occurs)
When assessing for use of lipid-lowering agents, ____ function tests should be assessed before and periodically throughout therapy. May cause an increase in levels.
liver
Two potential nursing diagnoses are?
Knowledge, deficient, related to disease processes and medication regimen

Noncompliance
IMPLEMENTATION:
See specific medications to determine ____ of doses in relation to ____.
timing
meals
Advise patient that these medications should be used in conjunction with diet restrictions which include?
fat
cholesterol
carbohydrates
alcohol

(also teach patient about exercise and smoking cessation)
EVALUATION:
Effectiveness of therapy can be demonstrated by?
decreased serum triglyceride and LDL cholesterol levels and improved HDL cholesterol ratios. Therapy is usually discontinued if the clinical response is not evident after 3 months of therapy.