Drug Class - Antituberculars

Front 1

Five antituberculars?

Back 1

ethambutol
isoniazid
pyrazinamide
rifampin
rifapentine

Front 2

What are general uses for antituberculars?

Back 2

used in treatment and prevention of tuberculosis

Front 3

What are combinations of antituberculars used for?

Back 3

treatment of active disease TB to rapidly decrease the infectious state and delay or prevent the emergence of resistant strains.
In selected situations, intermittent (twice weekly) regimens may be employed.

Front 4

Which aminoglycoside (p35) is also used as an antitubercular?

Back 4

streptomycin

Front 5

Which antitubercular is used in the prevention of meningococcal meningitis and Haemophilus influenzae type b disease?

Back 5

rifampin

Front 6

Antituberculars kill (tuberculocidal) or inhibit the growth of (tuberculostatic) ________ responsible for causing tuberculosis.

Back 6

mycobacteria

Front 7

Combination therapy with two or more agents is required, unless used as ______(isoniazid alone).

Back 7

prophylaxis

Front 8

Hypersensitivity and severe ____ disease is a contraindication.

Back 8

liver

Front 9

Use antituberculars cautiously in patients with a history of ____ disease or in elderly or debilitated patients.

Back 9

liver

Front 10

Ethambutol requires _____ follow-up.

Back 10

ophthalmologic

Front 11

Safety in pregnancy and lactation not established, although selected agents have been used without adverse effects on the fetus. Compliance is required for optimal response.

Back 11

okay

Front 12

Which antitubercular inhibits the metabolism of phenytoin?

Back 12

isoniazid

Front 13

Which antitubercular significantly decreases saquinavir levels (combination should be avoided)

Back 13

rifampin