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55 Cards in this Set

  • Front
  • Back
Name 2 groups of antipsychotics?
phenothiazines
miscellaneous
Name 5 phenothiazines?
chlorpromazine
Largactil, Thorazine

fluphenazine decanoate
{Modecate}, {Modecate Concentrate}, Prolixin Decanoate

fluphenazine enanthate
{Moditen Enanthate}, Prolixin Enanthate

fluphenazine hydrochloride
{Apo-Fluphenazine}, {Moditen Hcl}, {Moditen HCl-HP}, Permitil, Prolixin

prochlorperazine
Compazine, {Stemetil}, Ultrazine

thioridazine
{Apo-Thioridazine}, Mellaril, Mellaril-S, {Novo-Ridazine}, {PMS Thioridazine}

trifluoperazine
Eskazinyl, Eskazine, Jatroneural, Modalina, Stelazine, Terfluzine
Name 7 miscellaneous antipsychotics?
aripiprazole Abilify

clozapine Clozaril

haloperidol {Apo-Haloperidol}, Haldol, Haldol Decanoate, {Haldol LA}, {Novo-Peridol}, {Peridol}, {PMS Haloperidol}

olanzapine
Zyprexa, Zyprexa, Zydis

quetiapine
Seroquel

risperidone
Risperdal, Risperdal M-TAB

ziprasidone
Geodon
Antipsychotics are used in the treatment of acute and chronic ______, particularly when accompanied by increased psychomotor activity.
psychoses
Use of _____ is limited to schizophrenia unresponsive to conventional therapy.
clozapine
Selected antipsychotics are also used as ______ or _____.
antihistamines
antiemetics
_______ is an agent used in the treatment of intractable hiccups.
Chlorpromazine
What neurotransmitter do antipsychotics block and alter release and turnover of?
blocks dopamine receptors in the brain; also alters dopamine release and turnover
What are the peripheral effects of antipsychotics? (2)
anticholinergic
alpha-adrenergic blockade
Phenothiazines differ in the their ability to produce?
sedation
Sedation effects are greatest with with which 2 phenothiazine agents?
chlorpromazine
thioridazine
Extrapyramidal reactions are greatest with which 2 phenothiazine agents?
prochlorperazine
trifluoperazine
Anticholinergic effects are greatest with which phenothiazine?
chlorpromazine
Contraindications for antipsychotics include? (3)
hypersensitivity
cross-sensitivity may exist
between phenothiazines
don't mix with phenothiazines
don't mix with CNS
depressants
Use cautiously in?
pregnancy
lactation
symptomatic cardiac disease
severely ill
debilitated
diabetic
respiratory insufficiency
prostatic hypertrophy
intestinal obstruction
may lower seizure threshold
Clozapine may cause ______.
agranulocytosis
Most antipsychotics are capable of causing?
neuroleptic malignant syndrome
Antipsychotics should not be used routinely for anxiety or agitation NOT related to _____.
psychoses
Combining antipsychotics with alcohol, antihypertensives, or nitrates may have an additive ______ effect.
hypotension
Antipsychotics combined with ____ may decrease absorption.
antacids
Antipsychotics combined with phenobarbital may ______ metabolism and _______ effectiveness.
increase

decrease
Antipsychotics combined with other CNS depressants may cause additive CNS depression. Other CNS depressants include?
alcohol
antihistamines
antidepressants
opioid analgesics
sedative/hypnotics
Lithium may decrease ____ levels of antipsychotics and effectiveness of phenothiazines.
blood
Antipsychotics may (decrease, increase) the therapeutic response to
levodopa.
decrease
Antipsychotics may (increase, decrease) the risk of agranulocytosis with antithyroid agents.
increase
Assess patient's mental status (3 things) before and periodically throughout therapy.
orientation
mood
behavior
Monitor 3 things before and frequently during the period of dosage adjustment for antipsychotics.
blood pressure (sitting,
standing, lying)
pulse
respiratory rate
Observe patient carefully when administering medication to ensure medication is actually taken and not _______.
hoarded
Monitor patient for onset of ________ which is defined as restlessness or desire to keep moving.
akathisia
Monitor patient for ________ which is defined as difficulty speaking or swallowing, loss of balance control, pill rolling, mask-like face, shuffling gait, rigidity, and tremors.
parkinsonian
Monitor patient on antipsychotics for _____
which is defined as muscle spasms, twisting motions, twitching, inability to move eyes, weakness of arms or legs.
dystonia
Monitor patient taking antipsychotics for dystonia, akathisia, and parkinsonian every ___ months during therapy and _____ weeks after therapy has been discontinued.
2

8-12
Dystonia is most common in which age group?
younger
Parkinsonian effects are more common in which age group?
geriatric
Notify _____ if dystonia, akithisia, or parkinsonian effects occur, as reduction in dosage or discontinuation of medication may be necessary.
hcp
What 2 agents may be used to control dystonia, parkinsonian, and akathisia effects?
trihexyphenidyl
diphenhydramine
Monitor for ____ _____ which is defined as uncontrolled rhythmic movement of mouth, face, and extremities; lip smacking or puckering; puffing of cheeks; uncontrolled chewing; rapid or worm-like movements of tongue.
tardive dyskinesia
Notify hcp immediately if tardive dyskinesia effects are seen as these side effects may be _____.
irreversible
Monitor for _____ _____ syndrome which is defined as fever, respiratory distress, tachycardia, convulsions, diaphoresis, hypertension or hypotension, pallor, tiredness, severe muscle stiffness, loss of bladder control. Notify hcp immediately if these symptoms occur.
neuroleptic malignant
Potential nursing diagnoses?
(3)
Thought processes, disturbed
Knowledge, deficient, related
to disease processes and
medication regimen
Noncompliance
Keep patient _______ for at least _____ minutes following parenteral administration to minimize hypotensive effects.
recumbent

30
To prevent contact _____, avoid getting solution on hands.
dermatitis
Phenothiazines should be discontinued ___ hours before and not resumed for 24 hours following myelography, as they lower the _____ threshold.
48

seizure
With PO antipsychotics, administer with food, milk, or a full glass of water to minimize _____ irritation.
gastric
Dilute most concentrates in ____ ml of distilled or acidified tap water or fruit juice just before administration.
120
Advise patient to take medication exactly as directed and not to skip doses or double up on missed doses. Abrupt withdrawal may lead to? (7)
gastritis
nausea
vomiting
dizziness
headache
tachycardia
insomnia
Advise patient to make position changes slowly to minimize ____ _____.
orthostatic hypotension
Medication may cause _____. Caution paptient to avoid driving or other activities requiring alertness until response to the medication is known.
drowsiness
Caution patient to avoid taking _____ or other CNS depressants concurrently with this medication.
alcohol
Advise patient to use _____ and protective clothing when exposed to the sun to prevent ______ reactions. Extremes of temperature should also be avoided, as these drugs impair body temperature regulation.
sunscreen
photosensitivity
Advise patient that increasing activity, bulk, and fluids in the diet helps minimize the _______ effects of this medication.
constipating
Instruct patient to use frequent mouth rinses, good oral hygiene, and sugarless gum or candy to minimize dry mouth.
okay
Advise patient to notify hcp of medication regimen before treatment or _____.
surgery
Emphasize the importance of routine follow-up exams and continued participation in psychotherapy as indicated.
okay
Effectiveness of therapy can be demonstrated by ______ in excitable, paranoic, or withdrawn behavior. Relief of nausea and vomiting. Relief of intractable _____.
decrease

hiccups