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22 Cards in this Set
- Front
- Back
Name 2 groups of antifungals?
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systemic
topical / local |
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Name 10 systemic antifungals?
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amphotericin B deoxycholate
Fungizone amphotericin B cholesteryl sulfate Amphotec amphotericin B lipid complex Abelcet amphotericin B liposome AmBisome caspofungin Cancidas fluconazole Diflucan griseofulvin Fulvicin, Grisfulvin, Gris-PEG, Grisactin, Gristatin itraconazole Sporanox ketoconazole Nizoral terbinafine Lamisil |
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Name 16 topical/local antifungals?
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butaconazole Femstat-3, Gynezole-1, Mycelex-3
butenafine Lotrimin Ultra, Mentax ciclopirox Loprox, Pentac clotrimazole {Canesten}, {Clotrimaderm}, Fungoid, Lotrimin, Mycelex, Mycelex OTC, {Myclo}, {Neo-Zol} econazole Spectazole haloprogin Halotex miconazole Breezee Mist Antifungal, Lotrimin AF, Maximum Strength Desenex Antifungal, Micatin, Monistat-Derm, Zeasorb-AF naftifine Naftin natamycin Pimaricin nystatin Mycostatin, {Nadostine}, Nilsat, {Nyaderm}, Nystex, Pedi-Dri oxiconazole Oxistat sulconazole Exelderm terbinafine Lamisil AT terconazole Terazol tioconazole Monistat, Vagistat tolnaftate Aftate, Dr. Scholl's Athlete's Foot Cream, Dr. Schooll's Maximum Strength Tritan, {Pitrez}, Quinsana Plus, Tinactin, Ting |
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What are antifungals used for?
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treatment of fungal
infections |
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Infections of skin or mucous membranes may be treated with?
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topical or vaginal preparations
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Deep-seated or systemic infections require _____ or ______ therapy.
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oral or parenteral
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New parenteral formulations of _________ employ lipid encapsulation technology designed to decrease toxicity.
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amphotericin
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How do antifungals work?
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Kill (fungicidal) or stop growth of (fungistatic) susceptible fungi by affecting the permeability of the fungal cell membrane or protein synthesis within the fungal cell itself.
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Contraindications?
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previous hypersensitivity
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Most systemic antifungals may have adverse effects on _____ _____ function, so use cautiously in patients with depressed bone marrow reserve.
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bone marrow
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Which systemic antifungal commonly causes renal impairment?
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amphotericin B
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Which systemic antifungal requires dosage adjustment in the presence of renal impairment?
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Fluconazole
(Adverse reactions of fluconazole may be more severe in HIV-positive patients) |
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Interactions differ greatly among various agents.
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okay
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What should be assessed before and throughout therapy when taking antifungals?
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signs of infection
involved areas of skin and mucous membranes (increased skin irritation may indicate need to discontinue medication) |
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Potential Nursing Diagnoses?
(3) |
Infection, risk for
Skin integrity, impaired Knowledge deficit, related to medication regimen |
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For topical antifungals, consult hcp for ______ technique before applying medication. Wear gloves during application.
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cleansing
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When applying topical antifungals, do not use ______ dressings unless specified by physician or hcp.
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occlusive
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Patient/Family teaching tips?
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Instruct on how to use
medication form Continue medication as directed for full course of therapy, even if feeling better Report increased skin irritation or lack of therapeutic response to hcp |
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Effectiveness of therapy can
be demonstrated by? |
resolution of signs and symptoms of infection
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Length of time for complete resolution depends on? (2)
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organism
site of infection |
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Deep-seated fungal infections may require prolonged therapy (weeks-months).
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okay
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Recurrent fungal infections may be a sign of serious _____ illness.
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systemic
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