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22 Cards in this Set

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Name 2 groups of antifungals?
systemic
topical / local
Name 10 systemic antifungals?
amphotericin B deoxycholate
Fungizone

amphotericin B cholesteryl
sulfate
Amphotec

amphotericin B lipid complex
Abelcet

amphotericin B liposome
AmBisome

caspofungin
Cancidas

fluconazole
Diflucan

griseofulvin
Fulvicin, Grisfulvin, Gris-PEG, Grisactin, Gristatin

itraconazole
Sporanox

ketoconazole
Nizoral

terbinafine
Lamisil
Name 16 topical/local antifungals?
butaconazole Femstat-3, Gynezole-1, Mycelex-3

butenafine Lotrimin Ultra, Mentax

ciclopirox
Loprox, Pentac

clotrimazole
{Canesten}, {Clotrimaderm}, Fungoid, Lotrimin, Mycelex, Mycelex OTC, {Myclo}, {Neo-Zol}

econazole Spectazole

haloprogin Halotex

miconazole Breezee Mist Antifungal, Lotrimin AF, Maximum Strength Desenex Antifungal, Micatin, Monistat-Derm, Zeasorb-AF

naftifine Naftin

natamycin Pimaricin

nystatin Mycostatin, {Nadostine}, Nilsat, {Nyaderm}, Nystex, Pedi-Dri

oxiconazole Oxistat

sulconazole Exelderm

terbinafine Lamisil AT

terconazole Terazol

tioconazole Monistat, Vagistat

tolnaftate Aftate, Dr. Scholl's Athlete's Foot Cream, Dr. Schooll's Maximum Strength Tritan, {Pitrez}, Quinsana Plus, Tinactin, Ting
What are antifungals used for?
treatment of fungal
infections
Infections of skin or mucous membranes may be treated with?
topical or vaginal preparations
Deep-seated or systemic infections require _____ or ______ therapy.
oral or parenteral
New parenteral formulations of _________ employ lipid encapsulation technology designed to decrease toxicity.
amphotericin
How do antifungals work?
Kill (fungicidal) or stop growth of (fungistatic) susceptible fungi by affecting the permeability of the fungal cell membrane or protein synthesis within the fungal cell itself.
Contraindications?
previous hypersensitivity
Most systemic antifungals may have adverse effects on _____ _____ function, so use cautiously in patients with depressed bone marrow reserve.
bone marrow
Which systemic antifungal commonly causes renal impairment?
amphotericin B
Which systemic antifungal requires dosage adjustment in the presence of renal impairment?
Fluconazole

(Adverse reactions of fluconazole may be more severe in HIV-positive patients)
Interactions differ greatly among various agents.
okay
What should be assessed before and throughout therapy when taking antifungals?
signs of infection
involved areas of skin and
mucous membranes

(increased skin irritation may indicate need to discontinue medication)
Potential Nursing Diagnoses?
(3)
Infection, risk for
Skin integrity, impaired
Knowledge deficit, related to
medication regimen
For topical antifungals, consult hcp for ______ technique before applying medication. Wear gloves during application.
cleansing
When applying topical antifungals, do not use ______ dressings unless specified by physician or hcp.
occlusive
Patient/Family teaching tips?
Instruct on how to use
medication form
Continue medication as
directed for full course
of therapy, even if feeling
better
Report increased skin
irritation or lack of
therapeutic response to
hcp
Effectiveness of therapy can
be demonstrated by?
resolution of signs and symptoms of infection
Length of time for complete resolution depends on? (2)
organism
site of infection
Deep-seated fungal infections may require prolonged therapy (weeks-months).
okay
Recurrent fungal infections may be a sign of serious _____ illness.
systemic