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38 Cards in this Set

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What is osteochondrosis?

a disease of articular cartilage and subchondral bone, involving abnormal endochondral ossification along with osteochondral junction.

What disease is a clinical manifestation of OC with a separation of the osteochondral junction.

Osteochondrosis dessicans

What type of lesion is under a defect in the cartilage that is acting as a one way valve?

Subchondral bone cyst - this traps fluid and leads to an increase in pressure and necrosis of the bone


What the heck is a dirt lesion?

A common site for OCD - the Distal Intermediate Ridge of the Talus (DIRT)

What other regions in the hock are prone to OCD lesions?

lateral trochlear ridge of the talus, medial malleolus, medial trochlear ridge of talus

What place in the stifle is prone to OCD

lateral trochlear ridge of the distal femur, patella, medial femoral condyle *cyst* and the medial trochlear ridge of the femur.

Where in the shoulder does OCD occur most often?

the caudal humeral head.

Where in the fetlock does OCD occur most often?

distal condyle of MC3/MT3, saggital ridge, +/- palmar proximal P1

Where are some other odd areas that OCD occur?

elbow, growth plates and cervical vertebrae.

What is the most important factor for development of OCD?

Rapid growth rate

What part of the diet are we concerned about re: development of OCD?

High plane of nutrition/high concentrate/energy diet.

What kind of breeds are predisposed to OCD?

Warmbloods, Standardbreds, South German coldbloods, Hanoverian warmbloods, Dutch warmbloods.

Can exercise influence the number of OCD lesions that develop?

No

What period of time in a foals life does the # of OC lesions occur in?

5-11 months old.

What happens to collagen type II in OCD?

DECREASES

What happens to collagen type I in OCD?

INCREASES

Proteoglycan content _______ and Matrix metalloproteinase expression _____________

DECREASES, Increases

What do we use to dx OCD?

Signalment, Hx, CxS, lameness exam, rads and diagnostic arthroscopy

Who shows OCD?

young, fast growing horses, usually aged 6m-2 y

What are the CxS of OCD?

increased exercise *hx of) --> joint swelling, lameness, joint effusion, mild to severe lameness (and some may not show any lameness)

What diagnostic method do you utilize if the classic signs and Hx are there but the rads do not show OCD/OC?

Diagnostic arthoscopy (show the cartilage damage that is there even if there is minimal bone damage)

How young are the classic patients for OCD/OC?

6 months to 2 years

What samples can we collect to check for early biomarkers for OCD development?

Serum and synovial fluid


At 5 months old, collagen degradation has ________ correlation with OCD

Positive

At 11 months old, collagen degradation has ______ correlation with OCD development?

NEGATIVE

What biomarker of bone mineralization is high in those 2 weeks old that are predisposed to early OCD?

Osteocalcin

When do we want to dx OCD in order to be able to do medical management/prevention

by 5-11 months old.

What is the number one thing that we can do for foals who are starting to show signs of OCD?

Decrease the plane of nutrition.

What surgical treatment is the best for repair?

ARthroscopy - go in and take out the cartilage flaps, expose healthy bleeding bone and use ancillary treatments as needed.

What size of flap would be okay to try a PDS pin on?

> 2 cm with at least 50% of the circumference still attached.

What are the other ancillary treatments that can be done for OCD?

Chondrocyte/fibrin grafting; Micorpicking subchondral bone; Mosaicplasty; stem cell therapy.

In the hock - what treatments do you usually need to do?

Removal of flaps and curette under arthroscopy


In the femur/patella what treatments are you usually using?

Debridement + ancillary tx


What is the minimum recovery time needed for a post op OCD?

at least 6 weeks (may need up to 12 months if a STIFLE)

How long is the bandage left on post op?

3 weeks if possible

What is the px for this with a moderate to severe OCD lesion?

Guarded for return to soundness

What is the px for those will mild to moderate OCD lesions?

favorable for return to athletic activity

Which joint has the worst px?

Stifle, shoulder.