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14 Cards in this Set

  • Front
  • Back
What is the function of DNA?
Information and replication
What did Watson and crick discover about DNA?
double helix - a twisted rope ladder with the runs of the ladder composed of pairs of nucleotide bases joined by hydrogen bonds
Purines?
Adenine (A)
Guanine (g)
Pyrimidines?
Thymine (T)
Cytosine (C)
Uracil (U)
A joined to T by ? bond

G joined to C by ? bond
double

triple
All genetic information contained in our chromosomes is written in an alphabet composed of what?
four letters- AGTC
Steps for replication of DNA?
1.) A specific enzyme severs the hydrogen bonds linking the pairs of nucleotide bases
2.) New complementary bases are attracted to and attach to the bases on each of the separate strands
3.) The sugar-phosphate bonds between the new complementary bases are joined with the aid of an enzyme known as DNA polymerase - thus completing the duplication of the DNA molecule
Name three differences between DNA and RNA.
RNA has ribose rather than deoxyribose as the sugar group

RNA uses U instead of T

RNA is single stranded
Transcription
Transfer of genetic information from DNA to mRNA

uses RNA polymerase
Where does mRNA migrate after assembly?
Rough ER --> ribosomes for protein synthesis
Describe translation.
mRNA attaches to the ribosome

tRNA molecules line up along the mRNA template, which lines up the amino acids carried on the opposite ends of the tRNA molecules into a proper sequence to build a particular protein

amino acids bond together and the protein is formed
What are the two codes for tRNA?
one end - anticodon that may be complementary to a sequence of three bases (codon) on the mRNA template

the other end recognizes and binds a particular amino acid (depends on the 3-letter nucleotide base code)
Alphabet analogy for genetic information?
letters - AGTC
words - codons (3 letters)
vocabulary - 20 "words" (amino acids)
sentence (protein) typically contains 100-1000 words
allosteric protein
can change shape under certain physiological conditions, i.e. hemoglobin