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10 Cards in this Set

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  • Back

1927:


Studied pneumonia. Virulent, non-virulent

Frederick Griffith

1944:


transforming principle

Avery, McLeod, McCarty

1952:


infected E.coli with bacteriophage T2.

Hershey and Chase

1953:


Structure and function of DNA

Watson and Crick

Used chromatography to separate the four bases and quantify the amounts

Erwin Chargoff

Suggested bases were stacked like coins, 3.8 angstrom

William Astbury

Characteristic of a helical structure , 3.4 angstrom

Rosalind Franklin

Started growing E.coli in 15N-labeled medium then moved it to medium containing 14N. DNA replication is semiconservative.

Meselson-Stahl

isolated DNA polymerase 1 as the first enzyme involved in E.coli replication

Kornberg

developed triplet binding assay

Nirenberg and Leder