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37 Cards in this Set
- Front
- Back
nucleotide |
small units (monomers) that make up DNA |
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base pairing rules |
the bases of the 2 DNA strands always pair up in the same way (T-A, C-G); these pairings occur b/c of the sizes of the bases and the ability of the bases to form hydrogen bonds w/ each other |
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replication |
process by which DNA is copied during the cell cycle |
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DNA polymerase |
a group of enzymes that bonds the new nucleotides together |
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central dogma |
theory of molecular biology, which states that info flows in one direction, from DNA to RNA to proteins (discovered by Francis Crick and includes three processes: replication, transcription, and translation) |
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RNA |
ribonucleic acid; a chain of nucleotides, each made of a sugar, a phosphate group, and a nitrogen-containing base (temp. copy of DNA) |
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transcription |
process of copying a sequence of DNA to produce a complementary strand of RNA (gene is transferred into an RNA message) |
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intron |
unused portion that are removed from mRNA |
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exon |
used portion that bonds together |
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RNA polymerase |
enzymes that bond nucleotides together in a chain to make a new RNA molecule |
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messenger RNA |
an intermediate message that is translated to form a protein |
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ribosomal RNA |
forms part of ribosomes, a cell's protein factories |
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transfer RNA |
brings amino acids from the cytoplasm to a ribosome to help make the growing protein |
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translation |
process that converts, or translates, an mRNA message into a polypeptide |
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How is the structure of DNA a common language? |
the pairing of bases; strands fit together and are the opposite of each other |
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3 parts of nucleotides |
sugar, phosphate group, nitrogen-containing base |
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How many nucleotides compose DNA? |
~3 billion pairs |
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purines |
double-ring -> A and G |
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pyrimidines |
single-ring -> T and C |
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What kind of bond is formed between the bases and in the backbone? |
bases - hydrogen bondbackbone - covalent bond |
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steps of DNA replication |
1) DNA helicase unzips the two DNA strands (breaks hydrogen bond)2) free-floating nucleotides match up3) DNA polymerase reconnects the two strands4) Result: identical strands |
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role of enzymes in DNA replication |
to separate the DNA strands and reconnect the DNA bases |
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What kind of organic molecule are enzymes? |
proteins |
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How do you identify enzymes? |
-ase = forming name of enzymes |
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What molecule helps to ensure that DNA replication is accurate? |
DNA polymerase |
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codon |
sequence of 3 nucleotides that codes for one amino acid |
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stop codon |
stop codoncodon that signals to ribosomes to stop translation |
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start codon |
codon that signals to ribosomes to begin translation; codes for the first amino acid in a protein |
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anticodon |
set of 3 nucleotides in a tRNA molecule that binds to a complementary mRNA codon during translation |
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point mutation |
1 nucleotide is substituted for another (aa change) |
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mutation |
change in the DNA sequence |
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silent mutation |
does not change the amino acid formation |
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frameshift mutation |
insertion or deletion of a nucleotide; entire sequence of DNA/RNA after the mutation is shifted (much more serious to the structure and function of final protein) |
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gene translocation |
results from crossing over between non-homologous chromosomes |
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mutagen |
agent that can induce or increase the frequency of mutation in organisms (causes genetic mutations) |
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steps of transcription |
1) RNA polymerase separates the DNA nucleotides2) Free floating nucleotides match up w/ DNA3) mRNA breaks free in separate pieces4) mRNA processing takes place (introns removed, exons bond together)5) DNA recombines to be used again |
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How are mRNA codons translated into amino acids? (steps of translation) |
1) mRNA enters ribosome 2) Ribosome reads 1 mRNA codon at a time 3) tRNA delivers amino acids until a protein is created |