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36 Cards in this Set
- Front
- Back
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ID the cytokine(s):
Secreted by Th1 cells |
IL-2
IFN-y |
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ID the cytokine(s):
Secreted by Th2 cell |
IL-4, IL-5
IL-10 (inhibits Th1 and macrophages) |
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ID the cytokine(s):
Inhibits Th1 |
IL-10 from Th2
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ID the cytokine(s):
Induces diferentiation into Th1 cells |
IL-12
*Th1 initiates CMR (implies viral infection) |
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ID the cytokine(s):
Induces differentiation into Th2 |
IL-4
Th2 initiates HMR |
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ID the cytokine(s):
B cell stimulator(s) |
IL-4 and IL-5
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ID the cytokine(s):
Causes growth and activation of eosinophils |
IL-5
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ID the cytokine(s):
Secreted by Th and activates macrophages |
IFN-y
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ID the cytokine(s):
Pyogens secreted by monocytes and macrophages |
IL-1, IL-6, TNF-a
Acute phase cytokines |
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ID the cytokine(s):
Inhibits production of Th1 cells |
IL-10
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ID the cytokine(s):
Inhibits production of Th2 cells |
TNF-y
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ID the cytokine(s):
Mediates inflammation |
IL-1, IL-6, TNF-a
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ID the cytokine(s):
enhances synthesis of IgE & IgG |
IL-4
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ID the cytokine(s):
enhances synthesis of eosinophils |
IL-5
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ID the cytokine(s):
enhances synthesis of IgA |
IL-5
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ID the cytokine(s):
enhances synthesis of IgG |
IL-4
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ID the cytokine(s):
Released by virally infected cells |
INF-a
INF-b |
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ID the cytokine(s):
Supports growth and differentiation of bone marrow stem cells |
IL-3
(works like GN-CSF) |
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ID the cytokine(s):
Supports T cell proliferation, differentiation, and activation |
IL-2
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These Sx would be caused by an excess of which compliment?
Anaphylaxis |
↑ C3a, C5a
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These Sx would be caused by a deficiency in which compliment?
Hereditary angioedema |
C1 esterase
causes an ↑ in bradykinin |
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These Sx would be caused by a deficiency in which compliment?
Recurrent pyogenic sinus and respiratory tract infections |
C3
Causes an ↑ susceptibility to type III HSN - ↑ risk of s. pneumo, H. influenza infections |
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These Sx would be caused by a deficiency in which compliment?
Neisseria bacteremia |
C5-9 (Inability to form MAC)
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These Sx would be caused by a deficiency in which compliment?
Paroxysmal nocturnal hemoglobinuria |
DAF (GPI-anchored NZ)
Causes compliment-mediated lysis of RBCs |
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Which compliment is chemotactic for neutrophils?
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C5a
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Which compliment/surface proteins prevent compliment-activated attack of self cells?
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DAF
C1 esterase CD55 CD59 |
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What are the 3 chemokines for neutrophils?
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IL-8
C5a leukotriene B4 |
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Which cytokine increases MHC I & II expression on all cells?
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INF-y
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Cell surface proteins on all T-cells
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TCR - binds Ag-MHC complex
CD3 CD 28 - bind B7 on APC |
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Cell surface proteins on helper T cells
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CD4
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Cell surface proteins on cytotoxic T cells
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CD8
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Cell surface proteins B cells
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Ig (IgM/D binds Ag)
CD 19-21 |
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Cell surface proteins that is a receptor for EBV
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CD21 on B cells
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Cell surface proteins on macrophages
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MHC II
B7 CD40 CD14 - marker for MPs receptors for Fc of IgG (opsonin) CD56 - unique marker for NK cells |
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Cell surface proteins on all cells except mature RBCs
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MHC I
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Cell surface proteins that protect against compliment-mediated damage
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CD55
CD59 Found on WBC, RBCs, and platelets |
