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15 Cards in this Set
- Front
- Back
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HYQ: A teenage African American male presents to the ER with right hip pain and a Hct of 25%. What is the most likely diagnosis?
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Sickle Cell Anemia with Osteonecrosis of the femoral head
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HYQ: What is the next best step in the management of a pt with febrile neutropenia d/t chemotherapy?
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1) Admit
2) Blood and Urine Culture 3) Cefotime, Ceftotazime (IV broad spec abx) |
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HYQ: what is the MCC of anemia in the elderly?
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Iron deficiency anemia <--- blood loss <--- Colon CA
...or from poor diet |
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HYQ: what would you see on a blood smear of a pt with anemia d/t lead poisoning?
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Course basophilic stippling and microcytic hypochromic rbcs
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HYQ: what is the cause of anemia in an alcoholic pt with an elevated MCV?
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Folate deficiency
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HYQ: what is the cause of anemia that develops after taking a sulfa drug?
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G6PD deficiency
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HYQ: what medication is used in the long-term management of sickle cell anemia?
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Hydroxyurea --> increased Hgb-F
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HYQ: compare Iron deficiency Anemia to AoCD
Serum Iron Ferritin Transferrin |
IDA: ↓Serum Iron, ↓Ferritin, ↑ Transferrin
AoCD: ↓Serum Iron, ↑ Ferritin, ↓Transferrin |
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What lab markers suggest anemia d/t hemolysis?
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Low H&H
Schistocytes ↓ Haptoglobin ↑D-Dimer, ↑Indirect Bili, ↑LDH |
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What is the RBC d/o a/w...
Schistocytes Acanthocyte (Spur Cell) Bite Cell Basophilic stippling |
DIC, HUS, TTP
A-Beta lipoproteinemia G6PD Lead, Thalasemia, Alcohol |
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What is the RBC d/o a/w...
Peripheral neuropathy + sideroblastic RBCs Hypersegmented neutrophils Heinz bodies |
Lead posioning
Vit. B-12 deficiency, Folate deficiency G6PD |
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Which vaccines are particularly important in children with sickle cell disease?
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Pneumococcal, Flu, HepB, HiB
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Other than vaccination, how is pneumococcal infxn prevented in children with sickle cell dz?
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Prophyllactic Penicillin until 5 yr old
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What complication occurs in 10% of pts with sideroblastic anemia?
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Acute Leukemia
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Hereditary Spherocytosis:
Jaundice and Gall stones ____-omegaly __(inc/dec)__ MCHC Peripheral smear reveals ______ Positive _____ test |
Splenomegaly
Increased MCHC peripheral smear: Spherocytes (+) Osmotic fragility test |
