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29 Cards in this Set

  • Front
  • Back

What HPV strains cause skin warts?


What strains cause genital warts?

Strains 1 - 4 cause skin warts




Strains 6 & 11 cause non-cancerous genital warts

What organisms cause tinea infections?




How is it diagnosed?




What is the trx?

Causes - Microsporum, Trichophyton, Epidermophyton




Dx - KOH addition shows hyphae




Trx - Body → Topical clotrimazole, terbinafine, nystatins


- Scalp → Oral Griseofulvin


- Nails → Oral Terbinafine for prolonged time



What is intertrigo?




How is it diagnosed?




What is the trx?

Candida infxn in skin creases with satellite leisons




Dx = KOH shows pseudohyphae




Trx = Topical clotrimazole or terbinafine

What is the treatment for Scabies, lice, or crabs?




What is the treatment for pinworms?





Permethrin cream




Pyrantel or Me/Albendazole

What is the difference between Erythema Multiforme, Stevens-Johnson Syndrome (SJS), and Toxic Epidermal Necrolysis (TEN)?

Erythema Multiforme - target like lesions usually on hands/forearms that often spares mucous membranes




SJS - more severe, always involves mucous membranes, involves < 10% of body




TEN - Full thickness severe lesions involving >30% of body

What are the common causes of Erythema Multiforme?

HSV


Mycoplasma


Penicillin


Sulfa


NSAIDS


OCPs


Anticonvulsants

What is Seborrheic Dermatitis?


What is the trx?

Red plaques with greasy-looking yellow scales (craddle cap if on infants head)




Trx: Scalp → ketaconazole or SeS shampoo


Body → topical steroids

What is Seborrheic Keratosis?


What is the treatment?

Noncancerous warty "pasted-on" nodules




No trx needed

What infections are associated with Lichen planus?

HIV


Hep C

What are the different stages of decubitis ulcers?

Stage I - skin intanct, change in color only


Stage II - superficial


Stage III - full-thickness skin loss with damage to sub-Q tissues


Stage IV - destruction/necrosis of mm, bone, supporting structures

What is the difference between Pemphigus vulgaris and Bullous pemphigoid?




How are each treated?

Pemphigus vulgaris - flaccid bullae w/ + Nickoslky sign, + oral lesions, Anti-desmosome ab's in epidermis. Trx w/ High dose steroids




Bullous pemphigoid - Tense bullae w/ - Nickoslky sign, no oral lesions, Anti-hemidesmosome antibodies in BM, Trx w/ Topical steroids

What causes chronic blistering of sun-exposed skin and possible pseudoscleroderma?




What causes this disease?




RF?


Dx?


Trx?

Porphyria Cutanea Tarda


- Def in uroporphyringen decarboxylase


- RF = Hep C, EtOH, excess Fe


- Dx = ↑ plasma porphyrins


- Trx = Phlebotomy + Hydroxychloroquine

What are the 4 types of melanoma?

Superficial Spreading - MC, grows laterally then vertically later




Nodular - vertical growth, rapidly invasive




Acral Lentiginous - least common, on palms/soles/nailbeds




Lentigo Maligna - very slow vertical growth

What is the treatment for melanoma

Surgical Excision


- If "In situ" → ½ cm margin


- If < 2 cm in size → 1 cm margin


- If > 2 cm in size → 2 cm margin w/ LN dissection

What is trx for vitiligo?




What conditions is it associated with?

Topical Steroids (1st line) & avoid tanning




Tacrolimus (or other calcineurin inhibitors) if severe or resistant




Associated with hypothyroidism and autoimmune disorders

What is the name of the following lesions?




- Blue, compressible mass that does not regress


- Red-pink nodule on a child that is often confused w/ melanoma


- Diffuse stress-related hair loss

Cavernous Hemangioma




Spit Nevus




Telogen Effuvium

What is the USPSTF recommendations for Cholesterol screen in patients without CAD risk factors?

Start at age 35 in men


age 45 in females




Q 5 yrs

What are the following vitamins described?




- Niacin


- Ribofalvin


- Def causes ↑ RBC fragility


- Def causes peripherial neuropathy, angular cheliosis, and glositis

- Vit B₃ = Niacin




- Vit B₂ = Riboflavin




- Vit E




- Vit B₁₂



What is the order of default surrogate decision-maker in most states?

1) Patient's Spouse


2) Patient's Adult Children


3) Patient's Parents


4) Patient's Siblings


What are the 4 elements of a malpractice claim?

1) Duty of Care - Dr.'s obligation to conform to a reasonable standard of care


2) Breach of Duty - failure to conform to standard of care


3) Harm


4) Causation - breach of duty deemed to cause of harm

What is "Vicarious Liability?"

Supervisors are legally responsible for the actions of their those under their direct supervision

What are the formulas for sensitivity, specificity, PPV, and NPV?

What are the formulas for sensitivity, specificity, PPV, and NPV?

Sensitivity = A / A + C




Specificity = D / D + B




PPV = A / A + B




NPV = D / D + C

What is the formula for RR?
What do its values mean?
What study is it associated with?

What is the formula for RR?


What do its values mean?


What study is it associated with?



RR = (A / A+B) / (C / C+D)




RR > 1 = exposure ↑ risk of developing disease


RR = 1 = no association


RR < 1 = exposure ↓ risk of developing disease




*Used in Cohort Study

What is the formula for OR?
When does it estimate RR?
What study is it associated with?

What is the formula for OR?


When does it estimate RR?


What study is it associated with?

OR = (A/B) / (C/D)




Estimates RR when disease prevalence is low




*Used in Case-Control Study

What is the formula for AR?
ARR?
NNT?

What is the formula for AR?


ARR?


NNT?

AR = (A / A+B) - (C / C+D)




ARR = (C / C+D) - (A / A+B)




NNT = 1/ ARR

What is the formula for confidence interval?

CI = mean +/- (Z x SEM)




- If 90% CI, Z = 1.5


- If 95% CI, Z = 2


- If 99% CI, Z = 2.5

What percent of the study population falls within 1 SD, 2 SD's, 3 SD's of the mean if it assumed to have normal distribution?

1 SD = 68% of population




2 SD = 95% of population




3 SD = 99% of population

What is the difference between a Case-control and a Cohort Study?

Case-Control Study - Looks retrospectively at a group w/ disease (cases) and group w/out disease (controls) to ID risk factors. OR




Cohort Study - Usually prospectively looks at a group with risk factor exposure (cohort) to see if they develop disease. RR calculated

What are the following types of Biases?




- Screening detects slowly progressive cases of a disease and misses rapidly progressive diseases


- Subject's awareness of observation alters their reporting of subjective findings


- Study groups are not treated the same


- Pts with a certain med hx are more likely to participated in a study related to condition even though they don't represent pop

- Length Bias




- Observation Bias




- Procedure Bias




- Self-Selection Bias