Dispensing And Adr

Front 1

Type B or Bizarre type

Back 1

Anaphylaxis belongs to what type is ADR ?

Front 2

Adverse drug event

Back 2

It is defined as any event associated with the use of a drug in humans, whether or not considered as drug related.

Front 3

Salting-out

Back 3

It occurs when ions of the added electrolyte interact with water molecules and, thus, reduce the amount of water available for solution of the non-electrolyte.

Front 4

Type D or "delayed" ADR

Back 4

Teratogenicity and carcinogenicity are what type of ADR ?

Front 5

Addison's disease

Back 5

Sudden withdrawal of steroids can result what disease?

Front 6

Potentiation

Back 6

0 + 1 = 2

Front 7

Synergism

Back 7

1 + 1 = > 2

Front 8

Antagonism

Back 8

1 + 1 = 0

Front 9

Hypercalcemia and hypokalemia

Back 9

Give 2 conditions that amplify the activity of cardiac glycosides

Front 10

Phenylbutazone

Back 10

Warfarin is contraindicated with what drug and causing warfarin displacement resulting to hemorrhage and increased activity of warfarin?

Front 11

Phenobarbital and griseofulvin

Back 11

Give 2 drugs that are enzyme inducers of coumarin

Front 12

Gray baby syndrome

Back 12

A fatal cyanosis with symptoms of vomiting, abdominal distention and loose, green stools, owing to the inability of the infant to metabolize the drug.

Front 13

Chloramphenicol

Back 13

Gray baby syndrome is caused by what drug ?

Front 14

Herxheimer reaction

Back 14

A fever response to antibiotic therapy caused by the sudden release of endotoxins from various killed microorganisms.

Hint 14

Tetracycline - Lyme disease

Penicillin - Syphilis

Chloramphenicol - Typhoid fever

Front 15

Eutectic mixture

Back 15

Physical incompatibility manifested by lowering of melting point.

Front 16

Albumin

Back 16

What is the most common protein that binds to drug ?

Hint 16

It binds to acidic drugs.

Front 17

Glycoprotein and Lipoprotein

Back 17

What are the proteins that bind to basic drugs?

Front 18

Ototoxicity and Nephrotoxicity

Back 18

What are the common side effects of aminoglycosides ?

Front 19

Racemization

Back 19

The conversion of optically active form to an optically inactive form is called ?

Front 20

Polymorphism

Back 20

The existence of a substance in more than one crystalline form is called ?

Front 21

Polymerization

Back 21

The combination of two or more identical molecules forming a larger molecule.

Front 22

Co-solvents

Back 22

Are water-miscible solvent in which the drug has good solubility and are used in combination to increase the solubility of the solute.

Hint 22

Eg:

Ethanol, sorbitol, glycerin, PG, PEG.

Front 23

Drug dependence

Back 23

It is the physiological and psychological state resulting from drug administration dominating urge to use the drug periodically and repetitive.

Front 24

Drug habituation

Back 24

It is the psychological dependence to produce euphoric state of mind, absence if psychological dependence on or slight tendency to increase the dose.

Front 25

Drug tolerance

Back 25

It occurs when the dose needs to be increased after repetitive administration of the drug to maintain its effects.

Front 26

Drug tolerance

Back 26

It occurs when the dose needs to be increased after repetitive administration of the drug to maintain its effects.

Front 27

Drug addiction

Back 27

Is a state of periodic or chronic intoxication that is damaging and caused by repetitive use of drugs.

Front 28

Side-effects

Back 28

Are undesired consequences of the therapeutic effect of the drug.

Front 29

Type B or Bizarre type of ADR.

Back 29

Refers to totally abnormal effects, unrelated to the known therapeutic or pharmacologic action of the drug.

Hint 29

Example is anaphylaxis.

Front 30

Side effects

Back 30

Are predictable, dose dependent, and manifestation of the main pharmacological effect but occurring at some other site.

Front 31

Subscription

Back 31

Direction to the pharmacist - part of the prescription

Front 32

Superscription

Back 32

The Rx symbol in a prescription

Front 33

Inscription

Back 33

Medicine prescribed in a prescription

Front 34

SG = m/v

Back 34

Formula of specific gravity

Front 35

Signa

Back 35

Instruction to the patient - part of prescription

Front 36

Dimercaprol

Back 36

Indicated for As poisoning

Hint 36

Aka BAL (British anti-Lewisite)

Front 37

Epinephrine injection

Back 37

Immediate remedy for anaphylaxis

Front 38

Ferric salts

Back 38

Acacia + ______ = gelatinization

Front 39

Bismuth

Back 39

Acacia + ________ = Cementation

Front 40

Competition for tubular secre

Back 40

Probenecid and Penicillin exhibit this type of interaction

Front 41

Griffin scale

Back 41

Hydrophile Lipophile Balance system is also known as ?

Front 42

Auxiliary label

Back 42

It emphasizes important aspects of the dispensed medications : proper use, handling, storage, refill status, warnings or precautions

Front 43

Type C or Continuous type

Back 43

Ecstasy (MDMFA) exhibits this type of ADR

Front 44

Continuous type or type C

Back 44

Addiction falls under what type of ADR?

Front 45

Bizarre type

Back 45

Type of ADR that are totally abnormal effects unrelated to the known therapeutic or pharmacologic actions of the drug.

Front 46

Bizarre type

Back 46

Idiosyncratic reactions are consider what type of ADR ?

Front 47

Colestyramine

Back 47

An anionic exchange resin intended to bind acids, cholesterol metabolites and co-administered drugs

Front 48

Hermetically sealed

Back 48

This container is impervious to air and other gases under ordinary conditions of handling storage and transport

Front 49

Antioxidants

Back 49

BHT, BHA, sulfites, benzophenones and benzotriazoles are examples of ?

Front 50

Steven-Johnsons syndrome

Back 50

Exfoliative dermatitis is a characteristic manifestation of what syndrome ?

Front 51

0.065 g

Back 51

1 grain = ___ g

Front 52

30 mL

Back 52

1 fl.oz = ____ mL

Front 53

Antacids

Back 53

It is given with corticosteroids to reduce ulceration and bleeding

Front 54

Suspending agents

Back 54

Uses:

- Increase the viscosity of the vehicle.

- Slow down the rate of settling down.

- Cause the preparation to remain in suspension

Front 55

Chloral hydrate

Back 55

A trichloroethanol derivative of acetaldehyde and an effective sedative.

Front 56

Warfarin

Back 56

This drug inhibits the vitamin K dependent synthesis of clotting factors II, VII, IX, and X

Front 57

Acidic drugs

Back 57

Type of drug strongly bound to albumin

Front 58

Rx or superscription

Back 58

Petition for favor of healing and warning from great care and precaution

Front 59

Rx or Superscription

Back 59

It means "take thou" or "you take"

Front 60

Signa

Back 60

It means "mark thou"

Front 61

Indication

Back 61

The approved clinical use of the product based on substantial evidence of the efficacy and safety of the drug

Front 62

Precautions

Back 62

Instruction and special care to avoid undesired effects and to ensure the safe and effective use of the product

Front 63

- Opium and derivatives (heroin & morphine) - cocaine- LSD (lysergic acid diethylamide) - Indian hemp

Back 63

Examples of PROHIBITED DRUGS

Front 64

Includes "self-inducing" sedatives

- ( -barbital )

- amphetamine (Benzedrine or Dexedrine)

- Methaqualone or Nitrazepam (hypnotic drugs)

Back 64

Examples of REGULATED DRUGS

Front 65

INN - International Nonproprietary Names

Back 65

Facilitates the identification of pharmaceutical substances or active pharmaceutical ingredients

Front 66

Papyrus ebers

Back 66

This parchment scroll found in Egypt mentioned 700 drugs with formulas for more than 800 remedies

Front 67

De Materia Medica

Back 67

Contains 600 plants that were known to have medicinal properties

Hint 67

Written by Dioscorides

Front 68

Base

Back 68

The chief active constituent

Front 69

Principal display panel

Back 69

It comprises 40% of the total surface of the container.

Front 70

Violative

Back 70

A prescription where generic name is not written

Front 71

Violative

Back 71

Generic name is not legible and brand name is legible

Front 72

Violative

Back 72

"No substitution" is added

Front 73

Impossible

Back 73

Only generic name is written but is not legible

Front 74

Impossible

Back 74

When the generic name is the one in parenthesis

Front 75

Impossible

Back 75

Where the brand name is not in parenthesis

Front 76

Impossible

Back 76

Where more then one drug is prescribed on one prescription

Front 77

Essential drugs list or

National drug formulary

Back 77

It is the of drugs prepared and periodically updated by the DOH based on health conditions obtaining in the Philippines as well as on internationally accepted criteria.

Front 78

Core list

Back 78

List of drugs that meets the health care needs of the majority of the population (part of national drug formulary)

Front 79

Complementary list

Back 79

List of alternative drugs used when there is no response or has hypersensitivity reaction to the core essential, or core cannot be given. (part of national drug formulary)

Front 80

Complementary list

Back 80

List of alternative drugs used when there is no response or has hypersensitivity reaction to the core essential, or core cannot be given. (part of national drug formulary)

Front 81

Magnesium hydroxide

Back 81

Generic of Riopan

Front 82

Piroxicam

Back 82

Generic of Feldene®

Front 83

Zinc sulfate

Back 83

Salt of zinc that is valuable as an eyewash for the treatment of conjunctivitis

Hint 83

0.25%

Front 84

Zinc oxide

Back 84

Salt of zinc used in ointments as astringent and protestant

Front 85

Eutectic mixtures

Back 85

These are formed due to the lowering of melting points of the solid substances combined.

Front 86

Hygroscopic powder

Back 86

Substances which absorb moisture from the air

Front 87

Effervescent powders

Back 87

Powders that release carbon dioxide gas

Front 88

Anhydrous powders

Back 88

Powders that have no water of hydration/crystallization

Front 89

Efflorescent powders

Back 89

Powders that release water of hydration upon exposure to air

Front 90

Sulfonamides

Back 90

Urinary alkalinizer is administered with what drug to prevent crystalluria ?

Front 91

Benzalkonium chloride;

Antimicrobial agent in opthalmic solution

Back 91

What is the generic name of Zephiran® and its use?

Front 92

Idiosyncrasy

Back 92

Adverse drug reactions characterized by exaggerated or inordinate response to normal doses of a drug

Front 93

Sodium benzoate

Back 93

Substance used as a test for liver function by measuring the amount of hippuric acid in urine

Front 94

Reye's syndrome

Back 94

The risk of Aspirin in children with fever due to viral infection

Front 95

Aspirin

Back 95

Drug that should not be given to patients who have undergone surgery including dental surgery

Front 96

Aplastic anemia

Back 96

The most serious drug-induced blood disorder

Front 97

Aplastic anemia

Back 97

Characterized by acellular or hypocellular bone marrow

Front 98

Agranulocytes

Back 98

Characterized by marked reduction or disappearance of neutrophilic granulocytes in the peripheral blood

Front 99

Thrombocytopenia

Back 99

Characterized by platelet count below 100,000/mm³

Front 100

Antabuse® (Disulfiram)

Back 100

Used in the treatment of alcoholism by inhibiting the activity of aldehyde dehydrogenase

Front 101

Probenecid

Back 101

It increases serum levels and prolongs the activity of penicillin derivatives by blocking the latter's tubular excretion.

Front 102

Abdominal cramps

Back 102

Most common side effects of erythromycin therapy ?

Front 103

Chloral hydrate

Back 103

A drug that increases the anticoagulant action of warfarin because its metabolite competes with the anticoagulant for plasma protein

Front 104

Allopurinol

Back 104

It inhibits xanthine oxidase and thus increases the plasma levels of Mercaptopurine

Front 105

Augmented type

Back 105

Extension effect and side effect belongs to what type of ADR?

Front 106

Delayed type

Back 106

Teratogenesis and carcinogenesis belongs to what type of ADR ?

Front 107

Magnesium stearate

Back 107

It is used as a lubricant. The water proofing of this insoluble material can retard penetration by the gastrointestinal fluids and delay drug dissolution and absorption

Front 108

Titanium dioxide

Back 108

It is used as white pigment in creams and paints. Its major use is in sunscreens

Front 109

O/W

Back 109

Emulsions made with tweens are usually

Front 110

W/O

Back 110

Emulsions made with spans are usually

Front 111

Polyoxyalkene derivatives

Back 111

Spans and tweens are

Front 112

Keratolytic

Back 112

Primary use of salicylic acid?

Front 113

Sublimation

Back 113

Freeze drying is based on

Front 114

Sorbitol

Back 114

It is used as plasticizer in formulations of soft gelatin capsules

Front 115

Should be taken with meals

Back 115

Caution in taking Niacin

Front 116

Rifampicin

Back 116

It gives colored urine

Front 117

Surface evaporation

Back 117

A humectant retards what ?

Front 118

Potential toxicity

Back 118

Primary disadvantage of ethylene glycol as a solvent in oral preparations

Front 119

A micelle

Back 119

What is ferritin ?

Front 120

O/W

Back 120

Vanishing creams are classified as ?

Front 121

Tetracycline and fluoroquinolone

Back 121

Calcium may decrease the absorption of what drugs?

Front 122

Steven-Johnson's syndrome

Back 122

It is a blistering disorder, more severe than erythema multiforme.

Front 123

Sulfonamides

Back 123

Steven-Johnson's syndrome is a drug-induced hypersensitivity reaction caused by what drug ?

Front 124

Type F (failure of therapy)

Back 124

This type of ADR may result from non-compliance.