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11 Cards in this Set

  • Front
  • Back

sensitive to pH :


Acidosis increases


Alkalosis decreases


Rapid anaerobic collection recommended

ionized calcium

84 amino acid single chain polypeptide; Highly conserved (1-34); Intact PTH; rapidly metabolisedInactive mid/carboxyl terminal fragments; Longer half-life; Excreted via kidney; Two site IRMA assaysAmino terminalCarboxy terminal

Parathyroid hormone

if Post-operative hypocalcaemia1– 5 days after surgery + AnorexiaVocalisationTremorsTwitchingTetany and generalized seizures --- suspect:

Hypoparathyroidism

if Humoral hypercalcaemia; Lymphoma (20–40%)Anal sac adenocarcinoma (25-50%) / Other carcinomas / Local osteolytic hypercalcaemiaMultiple myeloma (20 %)Often sicker --- suspect:

Malignancy associated hypercalcaemia

if Young, female, pedigreeWaxing/waning illnessHyperkalaemiaHyponatraemiaAzotaemia, suspect

addisons

if increased tCa; Hyperphosphataemia ; zotaemiaIonised Ca normal/low (< 10 % high); Progression to tertiary hyperparathyroidism --- suspect:

Hypercalcaemia in renal disease

if older animal 4 – 17 years (dogs)Keeshounds / Siamese --- suspect:

Primary hyperparathyroidism

Polyuria/polydipsia; Urolithiasis/UTI; Lethargy/weakness; Kidney failure

cs hypocalcemia (dogs)

LethargyAnorexia Weight loss Palpable cervical nodule

cs hypocalcemia (cats)

if Accidental: FoodRodenticidesDay blooming jessamine; Calcipqotriol; suspect:

Hypervitaminosis D

Fluid therapy2 x MRFurosemide2 mg/kg q8hoursCalcitonin4-6 iu/kg sc every 8-24 hoursBisphosphonates

tx