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10 Cards in this Set

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  • Back

Describe how the D-value for a particular disinfectant is calculated.

A known concentration of test culture is exposed to a disinfectant for increasing times, at which point samples are withdrawn, neutralised, and plated to determine the residual infectivity.




The microbial population size (on a log scale) at different time points is plotted and the time taken to decrease the population size from 1000 to 100 (on a log scale) is the D-value.

Which of the following statements regarding chlorine is CORRECT?




A Chlorine-releasing compounds are highly active against both vegetative and spore-forming bacteria.


B It's efficiency is not decreased by the presence of soils.


C A major advantage of chlorine as a disinfectant is that it has a long shelf-life.


D A major disadvantage of chlorine is that it can be corrosive to metal surface at high concentrations.



D A major disadvantage of chlorine is that it can be corrosive to metal surface at high concentrations.

Which of the following statements regarding iodine is INCORRECT?




A It has a broad spectrum of antimicrobial activity, including sporicidal activity at high concentrations.


B Aqueous iodine is active over a wide range of pH values but iodophors are only active at acidic pH values.


C A major disadvantage of iodine is that is causes brown staining on surfaces including skin and clothing.


D Iodine compounds can be toxic at high concentrations.

B Aqueous iodine is active over a wide range of pH values but iodophors are only active at acidic pH values.

Which of the following statement regarding formaldehyde is CORRECT?




A It is active against vegetative bacteria, and mycobacteria. but not against fungi and most viruses.


B Its activity does not change in the presence of soil.


C It can be used in aqueous or gaseous forms.


D Formalin is an aqueous solution of ~37% formaldehyde put 20-30% methanol.

C It can be used in aqueous or gaseous forms.

Which of the following statements regarding glutaraldehyde is INCORRECT?




A 2% solutions are active against bacteria, fungi and viruses in less than 10 minutes.


B It is not suitable for medical devices as it is corrosive to metal surfaces.


C Its activity is decreased in the presence of soils.


D It is highly irritating to the skin and mucous membranes.

B It is not suitable for medical devices as it is corrosive to metal surfaces.

Which of the following is NOT a similarity between hydrogen peroxide and peracetic acid?




A They both break down into non-toxic by-products.


B They both are effective against bacteria, mycobacteria, viruses, fungi and spores.


C High concentrations can act as irritants to skin.


D They are bot used in the food industry due to the non-toxic nature of their by-products.

D They are bot used in the food industry due to the non-toxic nature of their by-products.

What alcohol(s) are most commonly used as disinfectants?




A Ethanol


B Isopropanol


C Methanol


D A and B only


E All of the above

D A and B only

Which of the following is NOT a disadvantage regarding the use of alcohols as a disinfectant?




A They are inactivated by the presence of soils.


B They are flammable and cannot be used near naked flames.


C They requires long contact times (minutes to hours) to be effective.


D They have little sporicidal activity.

C They requires long contact times (minutes to hours) to be effective.

Which of the following is NOT an example of a phenolic?




A Phenol


B Cresol


C Xylenol


D None of the above

D None of the above

Which of the following is an advantage of phenols as a disinfectant?






A They are generally active in the presence of soils.


B They are not corrosive to plastic and rubber surfaces.


C They are very effective against spores.


D They are not irritants to the skin and mucous membranes.

A They are generally active in the presence of soils.