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146 Cards in this Set

  • Front
  • Back

Metabolism

Totality of an organism’s chemical reactions

Metabolic pathways

A specific molecule is altered in a series of defined steps, resulting in a specific product

Catabolic
Complex molecules are broken down to simpler ones
Anabolic
Energy is consumed to build complex molecules from simpler ones
Energy
The capacity to cause change
Potential energy
Energy that is not kinetic, matter possesses it because of its location or structure
Kinetic energy

The relative motion of objects

Chemical energy
The potential energy, available for release in a chemical reaction
Thermodynamics
The study of energy transformations that occur in a collection of matter
1st Law Of Thermodynamics
Energy can be transferred and transformed but not created or destroyed
2nd Law of Thermodynamics
Energy that is transferred or transformed increases the entropy of the universe
Enthalpy
The total energy in a system
Entropy
The measure of disorder or randomness
Gibb’s free energy
The portion of the system’s energy that can perform work when temperature and pressure are uniform throughout the system
Exergonic reaction
The energy is outward, Delta G is negative and energy is released
Endergonic reaction
The energy is inward, Delta G is positive and energy is stored
Spontaneous reaction
A reaction that decreases the system’s free energy
Non-spontaneous reaction
A reaction that increases the system’s free energy
Enzymes
Catalytic proteins made up of amino acids
Equilibrium
The maximum stability - If Delta G = 0
Hydrolysis in ATP
A phosphate group is transferred from ATP to another molecule, that undergoes a change that performs work
Energy coupling
Manages cell resources by using an exergonic reaction to drive an endergonic one
Phosphorylation
The addition of a phosphate group to another molecule
Catalyst
A chemical agent that speeds up a reaction without being consumed by the reaction
Activation energy
The initial investment of energy for starting a reaction (the energy required)
Transition state
The summit of a reaction, so breaking and making of bonds can begin
Enzyme-substrate complex
When an enzyme binds to its substrate (Lock and key)
Induced fit
Similar to a clasping handshake, when the chemical groups of active site are brought into positions to help them catalyze the chemical reaction
Products
The results of a reaction
pH
Level of acidity
Temperature
A measure of the intensity of heat
Saturation
When a product enters an active sit, and another substrate molecule enters
Competitive inhibition
Reversible inhibitors that resemble substrate molecules and compete for admission into active sites - reduce productivity of enzymes by blocking substrates from entering active sites
Non-competitive inhibition
Impede enzymatic reactions by binding to another part of the enzyme and causing the enzyme to change shape
Allosteric regulation
Any case in which a protein’s function at an active site is affected by the binding of a regulatory molecule to a separate site-results in either stimulation oor inhibition of enzyme activity
Feedback inhibition
When ATP allosterically inhibits an enzyme in an ATP generated pathway-when a metabolic pathway is switched off by the inhibitory binding of its end product to an enzyme
Cofactors
Nonprotein component of enzymes
Coenzymes
An organic cofactor
Homoeostasis
The tendency of a system to maintain internal stability
Energy budget
Energy homeostasis
Herbivores
Animals that eat mainly plants and algae
Carnivores
Animals that eat other animals
Omnivores
Animals that consume animals and plants
Calories
2 units of energy
Malnourished
Animal whose diet is missing one or more essential nutrients
Undernourished
The stores of glycogen and fat are used up, body begins breaking down its protein for fuel and muscles decrease

Essential nutrients

Necessary in animal’s diet, must be obtained in preassembled form - 4 classes are essential amino acids, essential fatty acids, vitamins, and minerals
Ingestion
First stage of digestion, act of eating
Digestion
Second stage of digestion, process of breaking down food into molecules
Absorption
Third stage, cells absorb small molecules like sugars and amino acids
Elimination
Fourth stage, undigested material passes out of digestive compartment
Intracellular digestion
Digestion in the cell
Extracellular digestion
Digestion out of the cell
Peristalsis
Rhythmic waves of contraction by smooth muscles in wall of alimentary canal, pushes food along tract
Sphincters
Close of tube like drawstrings, regulating the passage of material between chambers of alimentary canal
Oral cavity
Mouth, triggers nervous reflex that causes salivary glands to deliver saliva to it
Pharynx
A junction that opens to both the esophagus and the windpipe (trachea)
Esophagus
Conducts food from pharynx down to the stomach by peristalsis
Stomach
Stores food and performs preliminary steps of digestion
Small intestine
More than 6 m long, where enzymatic hydrolysis of food macromolecules and absorption of nutrients into blood occurs
Large intestine
Also known as the colon, connected to the small intestine at a T-shaped junction where a muscular valve controls movement of material
Cecum
One arm of the t-shaped junction at the large intestine, a pouch
Appendix
Finger-like extension in the cecum
Liver
Produces bile
Pancreas
Produces hydrolytic enzymes and an alkaline solution rich in bicarbonate
Gall bladder
Where bile is stored before releasing to the small intestine
Duodenum
First part of small intestine, receives partially digested food from the stomach and begins the absorption of nutrients
Pepsinogen
The inactive form of pepsin
Pepsin
An enzyme that begins hydrolysis of proteins by breaking peptide bonds next to amino acids
Villi

Large circular folds in the lining of the wall of the small intestine

Microvilli

Muscular appendages exposed on the cells of villi
Mucus
A slippery secretion covering membranes
Bile

Mixture of substances stored in the gallbladder, aids in digestion and absorption of fats

Metabolism
Totality of an organism’s chemical reactions
Metabolic pathways
A specific molecule is altered in a series of defined steps, resulting in a specific product
Catabolic
Complex molecules are broken down to simpler ones
Anabolic
Energy is consumed to build complex molecules from simpler ones
Energy
The capacity to cause change
Potential energy
Energy that is not kinetic, matter possesses it because of its location or structure
Kinetic energy
The relative motion of objects
Chemical energy
The potential energy, available for release in a chemical reaction
Thermodynamics
The study of energy transformations that occur in a collection of matter
1st Law Of Thermodynamics
Energy can be transferred and transformed but not created or destroyed
2nd Law of Thermodynamics
Energy that is transferred or transformed increases the entropy of the universe
Enthalpy
The total energy in a system
Entropy
The measure of disorder or randomness
Gibb’s free energy
The portion of the system’s energy that can perform work when temperature and pressure are uniform throughout the system
Exergonic reaction
The energy is outward, Delta G is negative and energy is released
Endergonic reaction
The energy is inward, Delta G is positive and energy is stored
Spontaneous reaction
A reaction that decreases the system’s free energy
Non-spontaneous reaction
A reaction that increases the system’s free energy
Enzymes
Catalytic proteins made up of amino acids
Equilibrium
The maximum stability - If Delta G = 0
Hydrolysis in ATP
A phosphate group is transferred from ATP to another molecule, that undergoes a change that performs work
Energy coupling
Manages cell resources by using an exergonic reaction to drive an endergonic one
Phosphorylation
The addition of a phosphate group to another molecule
Catalyst
A chemical agent that speeds up a reaction without being consumed by the reaction
Activation energy
The initial investment of energy for starting a reaction (the energy required)
Transition state
The summit of a reaction, so breaking and making of bonds can begin
Enzyme-substrate complex
When an enzyme binds to its substrate (Lock and key)
Induced fit
Similar to a clasping handshake, when the chemical groups of active site are brought into positions to help them catalyze the chemical reaction
Products
The results of a reaction
pH
Level of acidity
Temperature
A measure of the intensity of heat
Saturation
When a product enters an active sit, and another substrate molecule enters
Competitive inhibition
Reversible inhibitors that resemble substrate molecules and compete for admission into active sites - reduce productivity of enzymes by blocking substrates from entering active sites
Non-competitive inhibition
Impede enzymatic reactions by binding to another part of the enzyme and causing the enzyme to change shape
Allosteric regulation
Any case in which a protein’s function at an active site is affected by the binding of a regulatory molecule to a separate site-results in either stimulation oor inhibition of enzyme activity
Feedback inhibition
When ATP allosterically inhibits an enzyme in an ATP generated pathway-when a metabolic pathway is switched off by the inhibitory binding of its end product to an enzyme
Cofactors
Nonprotein component of enzymes
Coenzymes
An organic cofactor
Homoeostasis
The tendency of a system to maintain internal stability
Energy budget
Energy homeostasis
Herbivores
Animals that eat mainly plants and algae
Carnivores
Animals that eat other animals
Omnivores
Animals that consume animals and plants
Calories
2 units of energy
Malnourished
Animal whose diet is missing one or more essential nutrients
Undernourished
The stores of glycogen and fat are used up, body begins breaking down its protein for fuel and muscles decrease
Essential nutrients
Necessary in animal’s diet, must be obtained in preassembled form - 4 classes are essential amino acids, essential fatty acids, vitamins, and minerals
Ingestion
First stage of digestion, act of eating
Digestion
Second stage of digestion, process of breaking down food into molecules
Absorption
Third stage, cells absorb small molecules like sugars and amino acids
Elimination
Fourth stage, undigested material passes out of digestive compartment
Intracellular digestion
Digestion in the cell
Extracellular digestion
Digestion out of the cell
Peristalsis
Rhythmic waves of contraction by smooth muscles in wall of alimentary canal, pushes food along tract
Sphincters
Close of tube like drawstrings, regulating the passage of material between chambers of alimentary canal
Oral cavity
Mouth, triggers nervous reflex that causes salivary glands to deliver saliva to it
Pharynx
A junction that opens to both the esophagus and the windpipe (trachea)
Esophagus
Conducts food from pharynx down to the stomach by peristalsis
Stomach
Stores food and performs preliminary steps of digestion
Small intestine
More than 6 m long, where enzymatic hydrolysis of food macromolecules and absorption of nutrients into blood occurs
Large intestine
Also known as the colon, connected to the small intestine at a T-shaped junction where a muscular valve controls movement of material
Cecum
One arm of the t-shaped junction at the large intestine, a pouch
Appendix
Finger-like extension in the cecum
Liver
Produces bile
Pancreas
Produces hydrolytic enzymes and an alkaline solution rich in bicarbonate
Gall bladder
Where bile is stored before releasing to the small intestine
Duodenum
First part of small intestine, receives partially digested food from the stomach and begins the absorption of nutrients
Pepsinogen
The inactive form of pepsin
Pepsin
An enzyme that begins hydrolysis of proteins by breaking peptide bonds next to amino acids
Villi
Large circular folds in the lining of the wall of the small intestine
Microvilli
Muscular appendages exposed on the cells of villi
Mucus
A slippery secretion covering membranes
Bile

Mixture of substances stored in the gallbladder, aids in digestion and absorption of fats