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118 Cards in this Set

  • Front
  • Back
What are the six major subdivisions of the digestive tract?
-oral cavity, teeth, tongue
-pharynx
-esophagus
-stomach
-small intestine
-large intestine
Which subdivision is responsible for mechanical processing, moistening, and mixing with salivary secretions?
oral cavity, teeth, tongue
What does the pharynx do?
propes materials into the esophagus
What does the esophagus do?
transports materials to the stomach
Where does chemical breakdown of materials and mechanical processing occur?
stomach
What does the small intestine do?
enzyme digestion, water, organic substrates vitamins, ions
What does the large intestine do?
enzyme digesion and absorption of water, organic substrates, vitamins, ions
What type of tissue is the oral cavity composed of?
stratified squamous epithelium
What does the mouth begin digestion of?
carbs and lipids
What prevents food from entering the pharynx prematurely?
uvula
What allows for expansion durng the passage of a large bolus?
musosa and submucoas folds
What keeps the lumen closed?
muscle tone
What are the three phases of swallowing?
1. buccal phase (voluntary)
2. pharyngeal phase (both
3. esophageal phase (involuntary
Where does the esophagus begin?
posterior to the cricoid cartilage
Describe the buccal phase.
begins with bolus against hard palate, tongue forces blus into oropharynx and elevates the soft palate.
Describe the pharyngeal phase.
begins when tactile receptors on the palatal arches and uvula are stimulated. Motor commands sent form medulla oblongat and contractions of muscle in pharynx occur
Describe esophageal phase.
begins as conteraction of pharngeal muscles forces the bolus through the esophagus. Bolus is pushed thorugh stomach by waves.
What occurs if a dry bolus travels slowly?
secondary peristaltic waves
What is the peritoneal cavity lined by?
peritoneum
What can the peritoneum be divided into?
visceral peritoneum-covers the organs in the peritoneal
parietal peritoneum-lines inner surface of body wall
The serous membrane lining the peritoneal cavity produces..
peritoneal fluid
What is the purpose of peritoneal fluid?
essential lubrication
What happens if there is no peritoneal fluid?
friction and irritation
What diseases accelerate the rate of fluids moving into the peritoneal cavity?
liver disease, kidney disease, heart failure
What does the accumulation of peritoneal fluid result in?
ascites
What are the three layers of the muscularis externa?
-longitudinal muscle layers
-circular muscle layer
-oblique muscle layer
What is the function of rugae?
allow the gastric lumen to expand
What are the four main regions of the stomach?
-fundus
-cardia
-body
-pylorus
What lines the rugae?
mucous cells for protection from secretions of exocrine cells
Whath do the rugae folds have?
gastric pits for th eoxocrine glands to drop their contents into
What is the pyloric sphincter?
regulates the release of chyme into the duodenum
What are the complete layers of the stomach wall?
1. Mucosa (gastric pits, lamina propria, muscularis mucosae
2. submucosa (artery and vein)
3. muscularis externa (oblique, circular, longitudinal )
4. serosa
Is the mucous produced by the stomach epithelium alkaline or acidic?
alkaline to defent against adic and enzymes in the gastric lumen
What secretes most of the acid and enzymes involved in gastric digestion?
gastric glands in the fundus
What types of cells are the gastric glands dominated by?
parietal cells and chief cells
how many mL of gastric juice does the gastric glands produce a day?
1500
What do exocrine glands form?
secretions form gastric juice
What is the function of mucous neck cells?
secrete mucus to protect our cells so we dont digest our stomach
What do parietal cells secrete?
-intrinsic factor
-hydrochloric acid
What is the purpose of intrinsic factor?
abscorb vitamin B12
What does parietal cells keep the pH of the stomach at?
1.5-2.0
Why doesnt parietal cells produce HCl into the cytoplasm?
it is too acidic and would erode secretory vesicles
What type of cells are G cells?
enteroendocrine cells
What doo G cells secrete?
gastrin
What is the function of gastrin?
-stimulates secretion by parietal and chief cells
-stimulates gastric wall contractions
What do D cells secrete?
somatostatin
What is the purpose of somatostatin?
-released adjacent to G cells
-inhibits the release of gastrin
What is the function of mucous neck cells?
secrete mucus to protect our cells so we dont digest our stomach
What do parietal cells secrete?
-intrinsic factor
-hydrochloric acid
What is the purpose of intrinsic factor?
abscorb vitamin B12
What does parietal cells keep the pH of the stomach at?
1.5-2.0
Why doesnt parietal cells produce HCl into the cytoplasm?
it is too acidic and would erode secretory vesicles
What type of cells are G cells?
enteroendocrine cells
What doo G cells secrete?
gastrin
What is the function of gastrin?
-stimulates secretion by parietal and chief cells
-stimulates gastric wall contractions
What do D cells secrete?
somatostatin
What is the purpose of somatostatin?
-released adjacent to G cells
-inhibits the release of gastrin
What is D cell release controlled by?
sympathetic nervous system
What happens to the D cell release when the parasympathetic nervous system increases?
they turn off
Where are hydrogen ions generated?
parietal cell
How are hydrogen ions generated in a parietal cell?
the enzyme carbonic anhydrase converts CO2 and H20 to carbonic acid
What is the release of somatostatin overriden by?
neural and hormonal stimuli
Where does the small intestin start and end?
starts at the pyloric sphincter, ends at the ileocecal valve
What are the three divisions of the small intestine?
-duodenum
-jejunum
-ileum
What is the purpose of plicae circulares?
-causes a turbulent flow through the intestines
-permanent folding of mucosa and submucosa
Do plicae circulares expand?
No
What are villi?
projections of absorptive epithelial layer
What is D cell release controlled by?
sympathetic nervous system
What happens to the D cell release when the parasympathetic nervous system increases?
they turn off
Where are hydrogen ions generated?
parietal cell
How are hydrogen ions generated in a parietal cell?
the enzyme carbonic anhydrase converts CO2 and H20 to carbonic acid
What is the release of somatostatin overriden by?
neural and hormonal stimuli
Where does the small intestin start and end?
starts at the pyloric sphincter, ends at the ileocecal valve
What are the three divisions of the small intestine?
-duodenum
-jejunum
-ileum
What is the purpose of plicae circulares?
-causes a turbulent flow through the intestines
-permanent folding of mucosa and submucosa
Do plicae circulares expand?
No
What are villi?
projections of absorptive epithelial layer
Where are villi largest?
duodenum, gradually narrow and shorten
What is the structure of the villi
epithelial columnar cells
What does each villus contain?
capillary bed and lacteal
What does a lacteal to?
transports materials that cant enter blood capillaries
-lymph vessels that absorb lipids
What gets fluid moving in the lacteals?
contractions of the muscularis mucosae
What are the layers of the small intestine?
1. mucosa
2. submucosa
3. muscularis externa.
4. serosa
What percentage of nutrient absorption occurs in the small intestine?
ninety
What segment of the small intestine is closest to the stomach?
duodenum
Where does the bulk of chemical digestion and nutrient absorption occur?
jejunum
What is the small intestine supported by?
mesentry
Which segment of the small intestine is the longest?
ileum
What does the ileum end with?
the ileocecal vavle
What is the purpose of the ileocecal valve?
controls the flow of material from the ileum into the cecum
What is the primary function of the duodenum?
recieve chyme from the stomach and neutralize its acids before they damage the absorptive surfaces
What is the submucosa of the duodenum dominated by?
duodenal glands that produce mucous secretions
Where is gastrin released and what is its function
in the stomach
-stimulates acid production by parietal cell san dstimualtion fo gastric motility; mixing waves increase in intensity
What hromones are secreted when chyme is in the duodenum?
-GIP
-secretin
-CCK
-VIP
What is the function of Gastric Inhibitory Peptide?
release of insulin from the pancreas
What is the function of secretin and CCK
stimulates release of pancreatic enzymes and buffers
-stimulates bile secretion and ejection of bile from gallbladder
What is the function of Vasoactive Intestinal Peptide (VIP)
dilation of intestinal capillaries
What does dilation of intestinal capillaries facililtate?
nutrient absorption
What does release of insulin from the pancreas facilitate?
nutrient utilization by all tissues
What happens when materials arrive in the jejunum?
nutrient absorption
What are the three phases of gastric secretion?
1. cephalic phase
2. gastric phase
3. intestinal phase
What are the three major function sof the large intestine?
1. reabsorption of water and compaction of intestinal contents into feces
2. absorption of important vitamins liberated by bacterial action
3. storage of fecal material
What are the three segments of the large intestine?
-cecum
-colon
-rectum
What is the function of the cecum?
collects and stores materials from the ileum and begins process of compatction
Compare the diameter and wall thickness of the large intestine vs. the small intestine.
the large intestine is larger in diameter and has thinner walls
What are the four regions we can divdide the coon into?
1. ascending colon
2. transverse colon
3. descending colon
4. sigmoid colon
What are the taeniae coli?
three longitudinal bands of muscle that run along the outside of the colon and corresopnt to the muscularis externa of other regions
What is the purpose of haustra?
permit the expansion and elongation of the colon
What are mass movements?
powerful peristaltic contractions that occur a few times a day
What is the rectum?
expandable organ for the temporary storage of feces
What triggers the urge to defecate?
movement of th efecal material into the rectum
What percentage of nutrient absorption occurs in the large intestine?
less than ten percent
What three vitamins does the large intestine absorbe?
k, b5 and biotin
How many mL of material enters the colon each day?
1500
How many mL of fecesis ejected?
200 mL
What does bacterial action produce that contribute to the odor of feces?
-ammonia
-indole
-skatole
-hydrogen sulfide
What are the major characteristics of the large intestine?
-lack of villi
-abundance of mucous cells
-presence of distinctive intestinal glands
What is the purpose of the mucus in the large intestine?
lubrication as fecal material becomes drier