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14 Cards in this Set

  • Front
  • Back
A hormone produced by the beta cells n the islets of Langerhans of th e pancreas.
insulin
Under normal conditions insulin is continuously released into the blood stream in small pulsatile increments called
a basal rate.
Under normal conditions insulin is continuously released into the blood stream in small pulsatile increments called a basal rate with increased release when food is ingested called a
a bolus.
the activity of released insulin lowers blood glucose and facilitates a stable, normal glucose range of aproximately
70-120 mg/dl
Glucagon, Epinephrine, growth hormone, and cortisol work to oppose the effects of insulin and are often referred to as
counterregulatory hormones.
These hormones work to:
-Increase blood glucose by stimulating glucose production and output by the liver

-Decreasing the movement of glucose into the cells
counterregulatory hormones
Often called prediabetes, usually occurs when the alteration of beta cell function is mild. Blood glucose levels are not higher than normal but not enough for diabetes diagnosis.
Impaired Glucose Tolerance (IGT)
CHARACTERIZED BY:
-ELEVATED INSULIN LEVELS
-HIGH LEVELS OF OF TRIGLYCERIDES
-DECREASED LEVELS OF LOW DENSITY LIPOPROTEINS (HDLs)
-INCREASED LEVELS OF LOW DENSITY LIPOPROTEINS (LDLs)
-HYPERTENSION
INSULIN RESISTANT SYNDROME
IF A PATIENT WITH TYPE 2 DIABETES HAS MARKED HYPERGLYCEMIA (50-1000MG/dL a sufficient endogenous insulin supply my prevent
DKA from occurring. However, osmotic fluid and electrolyte loss related to hyperglycemia may become sever and lead to hyperosmolar coma.
detected at 24-28 weeks of gestation and usually following an oral glucose tolerance test (OGTT)
Gestational Diabetes
CUSHINGS SYNDROME, HYPERTHYROIDISM AND THE USE OF PARENTERAL NUTRITION MAY CAUSE
SECONDARY DIABETES
CORTICOSTEROIDS (PREDNISONE), PHENYTOIN (DILANTIN), AND ATYPICAL ANTYPSYCHOTICS (E.G. CLOZAPINE [CLOZAPRIL]) ARE KNOWN TO INDUCE
DIABETES.
CLASSIC SYMPTOMS OF DIABETES MELLITUS ARE
POLYURIA (FREQUENT URINATION)
POLYDIPSIA (EXCESSIVE THIRST)
POLYPHAGIA (EXCESSIVE HUNGER)
POLYPHAGIA IS A CONSEQUENCE OF
CELLULAR MALNOURISHMENT