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16 Cards in this Set
- Front
- Back
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sulfonylurea moa
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keep K channel closed, causing depolarization, depolarizaTION STIMULATES Ca2+ influx into the beta cell, causes insulin exocytosis
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name first generation sulfonylureas
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acetohexamide, chloropropamide, tolazamide, tolbutamide
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name second generation sulfonylureas
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glimepiride, glipizide, glyburide
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meglitinides moa
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non-sulfonylurea secretagogue
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name meglitinides
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nateglinide, repaglinide
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biguanide moa
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decrease blood glucose independent of beta cells
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name biguanides
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metformin, metformin/glybuteride
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moa thiazolidinediones
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enhance insulin target tissue sensitivity
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name thiazolidinediones
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pioglitazone, rosiglitazone
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alpha-glucosidase inhibitors moa
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minimize absorption and digestion of ingested starch, SEVERE FLATULENCE
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name alpha-glucosidase inhibitors
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acarbose, miglitol
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aspart insulin, lispro insulin
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recombinant monomers - fast acting
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regular insulin
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physiologic onset. physiologic insulin is 2 zincs and 6 insulin hexamer
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NPH insulin
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insulin protamine mixture
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ultralente insulin
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poorly soluble zinc insulin, longer lasting
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glargine insulin
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microprecipitates at physiologic pH, long duration
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