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5 Cards in this Set

  • Front
  • Back
What causes spontaneous changes in DNA?
Oxidative damage
Hydrolytic attack
Methylation
Depurination
Deamination
What is a Mutagen?
A mutagen is an agent (physical or chemical) which can alter the structure or sequence of DNA.
What are the basics of DNA repair?
REPAIR =

Excision
+
Resynthesis
+
Ligation
What molecule leads the first step of base excision repair?
DNA glycosylase
How do repair systems recognize the damages?
DNA glycosylases

Many glycosylases for different types of DNA damages