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24 Cards in this Set
- Front
- Back
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warts. soft, tan-colored, cauliflower-like lesions with hyperkeratosis and koilocytosis. What is the cause?
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verruca vulgaris --> HPV
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intensely pruritic wheals, often covering large areas of abdomen. what is the mechanism?
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urticaria --> mast cell degranulation
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pruritic eruption, commonly on skin flexures. what is this associated with?
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atopic dermatitis --> associated with asthma, allergic rhinitis
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what type of hypersensitivity causes allergic contact dermatitis?
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typer IV (same as PPD test)
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papules and plaques with silvery scaling, especially on knees and elbows. what is diagnosis?
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psoriasis
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what histologic findings are caused by psoriasis?
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acanthosis with parakeratotic scaling, increased stratum spinosum, and decreased stratum granulosum.
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what is the most common location for psoriasis?
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scalp
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flat, greasy, pigmented squamous epithelial proliferation with keratin-filled cysts. appears to be "pasted on." present on head, trunk, and extremities. what is is?
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seborrheic keratosis
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what is vitiligo?
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irregular areas of complete depigmentation. caused by a decrease in melanocytes
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what are causes of necrotizing fasciitis?
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S. pyogenes and anaerobic bacteria. causes crepitus from methane and CO2 production
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superficial skin infection with honey-colored crusting. what is the cause?
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impetigo --> caused by S. aureus or S. pyogenes
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where should you get your sample to culture for the cause of SSSS?
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Staph aureus from the leading margin of the wound
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what is destroyed by the toxin in SSSS?
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exotoxin destroys keratinocyte attachments in the stratum granulosum only
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white painless plaques on the tongue that cannot be scraped off. what is the cause?
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hairy leukoplakia --> EBV mediated. specific for HIV infection
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what is cause of bullous pemphigoid?
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autoimmune disorder with IgG antibody against hemidesmosomes. is subepidermal
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what is pemphigus vulgaris?
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autoimmune disorder with IgG antibodies against desmosomes (intraepidermal). acantholysis of skin and oral mucosa. shows linear IF
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what dermatologic problem is associated with celiac disease?
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dermatitis herpetiformis
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what is the mechanism of dermatitis herpetiformis?
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deposits of IgA at the tips of dermal papillae cause pruritic papules and vesicles
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pruritic, purple, polygonal papules with sawtooth infiltrate of lymphocytes at dermal-epidermal junction. what is it?
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lichen planus
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what is actinic keratosis?
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premalignant lesions caused by sun exposure. small, rough, erythematous to brownish papules.
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what is acanthosis nigricans and with what is it associated?
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hyperplasia of stratum spinosum. associated with hyperlipidemia (from cushings disease, diabetes) and visceral malignancy
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locally invasive lesion in sun-exposed areas (behind ears) with rolled edges and central ulceration. what is the diagnosis?
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basal cell carcinoma
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what is the tumor marker for melanoma?
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S-100
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what is the best indicator of prognosis for a malignant melanoma?
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depth of invasion
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