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15 Cards in this Set
- Front
- Back
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Calciphylaxis
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• Rare and fatal (80%)
• Female (3:1) • ESRD (1%), diabetes? Obesity?, post renal transplant (30%), liver dx, HIV • Secondary hyperparathyroidism – Parathyroidectomy? Proof? • Red plaques in livedo pattern, become black gangrenous plaques • Bilateral and symmetrical |
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treatment for calciphylaxis
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Treatment: debridement, HBOT,
parathyroidectomy, bisphosphonates, IV sodium thiosulfate (antioxidant that reduces pain) |
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skin signs of renal disorder
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• Edema on LE, Xerosis
• Pruritus: not clearing metabolites? • Half and half nail: proximal nail is white, distal is red-brown, 10% of patients with renal dx • Clears after renal transplant |
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skin signs of hepatic problems
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Color: Jaundice—deposition of bilirubin in
skin, greater than 2.5 mg/dl Pruritus: bile salts in skin Koilonychia (spoon nails) Terry’s Nails (aka leukonychia on all of nail except for 1-2 mm area) Hepatitis C infection: cryoglobulinemia/palpable purpura |
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skin signs of thyroid problems
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• Pretibial myxedema
(Thyroid dermopathy): in Graves dx; shiny, waxy indurated plaques on anterior tibia. Peau d’orange appearance • Dry, xerotic skin and decreased hair in hypOthyroidism • Hyperhidrosis in hypErthyroidism |
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Dermatological manifestations of Diabetes Mellitus
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• Prayer sign
• Necrobiosis Lipoidica Diabeticorum • Bullous Diabeticorum • Acanthosis Nigricans • Diabetic Dermopathy • Granuloma Annulare • Infections: Tinea, Onychomycosis, Skin • Yellowish nails • Ulcers • Xerosis |
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what is prayer sign
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• “Diabetic Hand
Syndrome” • Inability to appose palmar surfaces when pressing hands together • Waxy thickening of dorsal aspect of hands and fingers • NIDDM and IDDM |
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what is necrobiosis lipodica diabeticorum
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• Slightly elevated irregular plaque on the
pre-tibial region • Becomes yellowbrown looking and atrophic in center • 1/3 lesions ulcerate spontaneously 10 year delay in those who have Diabetes • More common in women |
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Treatment of necrobiosis lipodica diabeticorum
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• Topical steroids under
occlusion • Intralesional Kenalog 10 • Short term oral steroids in nonulcerated • Prevent secondary infection if open • Only 11-65% have diabetes, but sending for lab eval is useful |
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What is bullosis diabeticorum
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• Tense blisters appearing on feet, plantar
aspect, legs • Self-limiting • No scars, negative Nikolsky’s sign • Chronic and recurring |
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What is acanthosis nigricans
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• Velvety hyperpigmented plaques on the
neck and axilla • Dirty skin that can’t be washed off • Insulin resistance: often high levels of insulin are present in the plasma |
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What is diabetic dermopathy
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• Brown atrophic spots on legs
• Most common sign of diabetes • Shown that this correlates with high HgA1c • More common in men |
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most common fungal skin infection in a diabetic is…
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CANDIDA ALBICANS
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what kind of tremor do you have in parkinson
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essential
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What kind of cancers typically metastasize to spien
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lung, breast, prostate
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