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31 Cards in this Set
- Front
- Back
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What are the layers of epidermis? |
stratum corneum, stratum granulosum (granular cell layer), stratum spinosum, basal cell layer |
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What does the stratum corneum contain? |
most mature corneocytes keratin and fillagrin surrounded by lipid matrix (provides water barrier) |
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What is fillagrin? |
PRO in the granular cell layer holds water mutations- atopic dermatitis |
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What layers are in the dermis? |
papillary dermis reticular dermis |
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what cell types can be in dermis? |
fibroblasts- healing mast cells- inflm, urticaria |
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what is a keloid scar? |
overproductin and deposition of collagen at site of dermal injury |
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What are hypertrophic scars? |
overactivity of collagen
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What are some differences btwn hypertrophic and keloid scars? |
hypertrophic: fast progression (few days), followed by regression keloid: slower progression, NO regression |
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What are the 4 things you look at during the skin exam? |
type shape arrangement distribution |
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what are the 3 types of skin lesions? |
flat, elevated, depressed |
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What are some examples of flat lesions |
macule petechiae ecchymosis telangiectasia purpura |
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What is blanching? |
use microscope slide to press on skin lesion, if it turns white that means blood vessels are intact |
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What is a papule? |
raised, solid lesions <0.5cm |
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What is a nodule? |
raised, solid lesions >0.5cm |
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What is a plaque? |
plateau-like elevation, confluence of papules |
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What is lichenification? |
chronic, thickening of epidermis leading to exaggerated, deep skin lines |
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What is lichenificaiton usually due to? |
chronic rubbing/scratching |
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What is a wheal? |
round or flat topped evanescent lesion broad flares of edematous skin change rapidly in size and shape |
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What is a urticaria? |
multiple wheals hives |
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What is a pustule or abscess? |
superficial lesion filled with purulent exudate- white, yellow, green
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What is a furuncle? |
a pustule of abscess that has a hair follicle |
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What is a carbuncle? |
multiple furuncles |
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What is an example of a depressed lesion? |
ulcer |
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What do you look for as far as shape? |
round VS irregular well demarcated borders |
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What do you look for as far as arrangement? |
singular lesion VS clusters linear distribution uniform in color |
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What do you look for as far as distribution? |
location does it follow dermatome |
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What are 2 ways of Dx a skin lesion? |
KOH prep Wood's lamp |
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What are 2 examples of rashes you can see under a Wood's lamp? |
vitiligo, erythrasma |
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What are basic Tx for a skin lesion |
cryotherapy shave biopsy excisional biopsy mohs surgery |
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What are indications to use cryotherapy? |
warts, seborrheic keratoses, actinic keratoses |
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How is cryotherapy done? |
Qtip dipped and liquid nitrogen freeze for 3-5s to create freeze ball 1-3mm rim surrounding lesion thaw 20s |
