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36 Cards in this Set
- Front
- Back
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Orthokeratosis
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Basket weave of SC (normal)
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If you don't see orthokeratosis
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something is affecting the SC
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Parakeratosis
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Retained nuclei in SC
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Acrosyringium
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sweat glad coil in the epidermis, corkscrew out into SC
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How do sweat ducts look in dermis vs epidermis
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Straight in dermis, coiled in epidermis
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Hamartoma
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Normal tissue in a normal place in an abnormal amount
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Papillary dermis vs. reticular dermis
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Papillary = lighter, pinker, can extend down around the adnexal structures, aka- adventitial dermis
Reticular = darker, thicker |
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Crenulation
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Nuclei indented (pushed)
ex = nuclei in a sebaceous glad |
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Follicular infandibulum
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Normal potion of top of hair follicle, where acne occurs (out into epidermis)
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Erector pili muscle vs. Nerve
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Erector pili: (inferior segment of follicle), cigar shaped nuclei
Nerve: wavier nuclei, more delicate nuclei, fine wavey end and more slender |
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Two kinds of sweat glands
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Apocrine vs eccrine
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Another name for spinous layer of epidermis
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Malpigian layer
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Three types of secretions:
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Merocrine or eccrine = by exocytosis
Apocrine = decapitation secretion Holocrine = membrane rupturing (sebaceous) |
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Characteristics of sebaceous glands with hair follicles
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Bigger gland, smaller follicle
Smaller gland, bigger follicle |
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Trichilemmal differentiation
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clearing around nuclei in follicle
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Characteristics of SK
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-tumor of epithelium
-horn cyst (pseudocyst) -acanthotic epithelium |
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Ulcer
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Loss of epidermis, the dermis is exposed
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Erosion
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Partial loss of the epidermis
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Dyskeratosis
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Abnormal individual-cell keratinization, prematurely keratinized
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Acantholytic dyskeratosis
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Holes, pink keratin in lower epidermis; seen in Grover's, Darier's, Halle Halle; will see corps ronds and grains (a way to describe the keratinocytes)
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Corps rond
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Owls eye, rouded nucleiu with halo of pale/pink dyskeratotic cytoplasm
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Grain
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Dark spots, blue flattened nucleus surrounded by minimal dyskeratotic cytoplasm
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Cells in the epidermis
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Keratinocytes (90%), Melanocytes (1 in 10, in basal layer)
Merckle cells Langerhans cell Lymphocytes |
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Pagetoid extension
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Melanocytes moving up into epidermis
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Merckle cell function
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Modified touch cell, look a lot like melanocyte, located around hair follicle
(can have Merckle cell cancer) |
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Dermal papillae vs. rete ridge
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Dermal papillae come up
Rete ridge is epidermis that extends down |
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What does eczema look like on histology
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spongiosis in epidermis, parakeratosis, lymphocytic infiltrate (if PMNs, it's allergic)
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Spongiosis
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INTERcellular edema in epidermis with stretching of cell-cell junctions
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Where is the pigment kept?
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Melanocytes give keratinocytes the melanin; if keratinocyte dies/spills, gobbled up by the histiocytes (macrophages)
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Granuloma
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collection of histiocytes
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Where does melanocyte keep the melanin
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Melanosome
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Where does keratinocyte keep the melanin
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above the nucleus, protect the DNA
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ki-67
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proliferative marker (a lot will stain in the basalar layer, normally proliferating there)
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Regression
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scarring, fibrosis, telangiectasia; (after a battle); see in the papillary dermis
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What is special about inflammatory infiltrate of melanoma
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Plasma cells. Most inflammatory infiltrate doesn't have plasma cells
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Epidermotropism
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Lymphocytees (LARGE, atypical?) in epidermis with relative absence of spongiosis; term usually reserved for MF and CTCL
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