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22 Cards in this Set
- Front
- Back
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old lady, Jewish, begins in mouth
(+) Nikolsky's blistering w/ split low in epidermis |
pemphigus vulgaris
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onset like pimple
SEVERE PAIN high WBC, high T crepitus, doughy to palpation air on XR |
necrotizing faciitis
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what is the MC cause of necrotizing faciitis?
what predisposes? |
GAS (group A strep)
DM, PVD, trauma |
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diffuse progressive rash
malaise, fever PMH atopic eczema diffuse tense vesicles w/ erythema halo lymphadenopathy, fever, tachycardia |
kaposi's varicelliform eruption (eczema herpeticum)
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what is kaposi's varicelliform eruption?
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aka eczema herpeticum
secondary infection of atopic eczema, usually HSV |
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h/o psoriasis
multiple erythematous scaled plaques lymphadenopathy |
mycosis fungoides
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cutaneous T-cell lymphoma
males indurated |
mycosis fungoides
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chills, fever, malaise, MOUTH ulcers
PMH: "spider bites" mult blistering lesions onset as erythematous sheets that desquamate w/ minimal contact |
SJS
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immune complex-mediated hypersensitivity rxn
causes: drugs & infection (+) Nikolsky's early targetoid |
SJS
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what are the etiological agents in SJS?
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sulfonamides, amino-PCN's, cephalosporins, phenobarbital, carbamazepine, calproic acid, allopurinol
mycoplasma pneumonia, yersinia, herpes |
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what is the Tx for SJS?
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fluids, burn unit, NO SILVADENE/ SULFUR, no corticosteroids, give Ig
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what is the calculation for fluid administration for SJS?
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4x(%burn) x (wt in kg) = cc's to give in 52hrs, but give first 1/2 in first 8 hrs
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chills, malaise, diffuse peeling rash (>30%)
PMH: mult UTIs |
TEN (toxic epidermal necrolysis)
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(+) Nikolsky's
fever, leukoplakia confluent erythema outer layer epidermis separates form basal drug-induced |
TEN
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deep swelling
face, distal extremities acquired form assoc w/ urticaria no pruritis |
angioedema
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how do ACEI's cause angioedema?
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angiotensin 2 decreased, decreasing metabolism of [thus increasing] bradykinin which vasodilates and increases permeability; fluid then goes into tissues
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what is the Tx for angioedema?
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EPI, antihistamines, corticosteroids
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purpura on infant
immune deficient (on Abx or recent infection/ fever) |
meningicoccal sepsis
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what is the Tx of meningicoccal sepsis?
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Abx, fluids, PICU
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Asx, nonpruritic lesion
raised, dark ring around it scalp FHx risk factor |
malignant melanoma
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pale, afebrile, fatigued pt
spots on tibia, mouth low PLT count (N = 100k), predominance of blasts |
acute lymphocytic leukemia
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what is the MC childhood malignancy in US?
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leukemia; 75% lymphoblastic
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