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49 Cards in this Set

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Precancerous skin lesions: Actinic keratoses

- Sun exposed areas 
- Small, rough, scaly lesions d/t prolonged sun exposure
- Common in fair skinned people, typically on face


biopsy to exclude squamous cell carcinoma 


tx: 5-FU topical, 5% imiquimod cream, topical diclofenac gel or photody...

- Sun exposed areas


- Small, rough, scaly lesions d/t prolonged sun exposure


- Common in fair skinned people, typically on face




biopsy to exclude squamous cell carcinoma




tx: 5-FU topical, 5% imiquimod cream, topical diclofenac gel or photodynamic therapy

Basal cell carcinoma

- Most common skin cancer 
- Risk: sun exposure, fair skinned, most common on nose


PE: Classic appearance pearly, smooth papule w/ roles edges & surface telangiectases (3 p's: pearly, pink, papule)


*Metastasis is rare, but can be locally destr...

- Most common skin cancer*


- Risk: sun exposure, fair skinned, most common on nose




PE: Classic appearance pearly, smooth papule w/ roles edges & surface telangiectases (3 p's: pearly, pink, papule)




*Metastasis is rare, but can be locally destructive




Tx: surgery

Squamous cell carcinoma

- Less common than SCC
- Risks: sun exposure, actinic keratoses, chronic skin damage, immunosuppressive therapy 


PE: crusting, ulcerated nodule or erosion, red conical hard lesions


*Metastasis is higher than BCC, lower than melanoma
*90% cause...

- Less common than SCC


- Risks: sun exposure, actinic keratoses, chronic skin damage, immunosuppressive therapy




PE: crusting, ulcerated nodule or erosion, red conical hard lesions




*Metastasis is higher than BCC, lower than melanoma


*90% cause = HPV




Tx: excision



Melanoma

- Most aggressive form of skin cancer & #1 cause of death d/t skin cancer


Risks: fair complexion, inability to tan, easily sunburned, red hair &/or freckles, numerous moles

- Most aggressive form of skin cancer & #1 cause of death d/t skin cancer




Risks: fair complexion, inability to tan, easily sunburned, red hair &/or freckles, numerous moles

Steven-Johnson Syndrome (Erythema multiforme)

- Target like, "bulls eye", multiple lesions
- Abrupt eruption
- Hives, blisters, petechiae, purpura & hemorrhagic that are painful
- Mucosal surface involvement (eyes, nose, mouth, esophagus)
- Fever or flu-like sx before rash

Causes: medicines...

- Target like, "bulls eye", multiple lesions


- Abrupt eruption


- Hives, blisters, petechiae, purpura & hemorrhagic that are painful


- Mucosal surface involvement (eyes, nose, mouth, esophagus)


- Fever or flu-like sx before rash




Causes: medicines (PCN, sulfa, barbs, phenytoin), infections, malignancies




Tx: Supportive




*HIV pts @ inc risk

Skin clinical findings: Benign

Seborrheic keratoses: senile wart, raised pink, d/t aging, tx: ammonium lactate




Xanthelasma: raised plaque around eye -- sign of hyperlipidemia




Melasma: mask of preg or birth control, brown/tan stains upper cheeks & forehead, permanent, lighten over time




Vitiligo: hypopigmented patches of skin




Cherry angioma: benign small red papules, inc w/ age




Lipoma: painless cystic tumors on subq layer of skin (neck, trunk, legs, arms)




Nevi (moles): round macules to papules




Xerosis: inherited, extremely dry skin




Acanthosis nigricans: thickening of skin (neck & axilla). a/w DM, metabolic syndrome, obesity, GI cancer




Dermatofibroma: legs most common, slow growing round firm nodule -- fitzpatrick's sign (retracts when squeeze)




Lentigines: small brown patches on elderly



Psoriasis

- Inherited, chronic skin disorder 
- Pruritic erythematous plaques w/ fine silvery white scales, symmetrical (scalp, elbows, knees, sacrum, intergluteal folds)
- May also c/o swollen joints (a/w arthritis)

Tx: topical corticosteroid or retinoi...

- Inherited, chronic skin disorder


- Pruritic erythematous plaques w/ fine silvery white scales, symmetrical (scalp, elbows, knees, sacrum, intergluteal folds)


- May also c/o swollen joints (a/w arthritis)




Tx: topical corticosteroid or retinoids




*alcohol can trigger a


lesion

Atopic dermatitis (eczema)

- Chronic inherited skin disorders, extremely pruritic rashes (hands, flexural folds, neck)
- Small vesicles that rupture leaving bright red weepy lesions
- Exacerbated by stress, winter, etc.
- A/w asthma, allergic rhinitis, multiple allergies ...

- Chronic inherited skin disorders, extremely pruritic rashes (hands, flexural folds, neck)


- Small vesicles that rupture leaving bright red weepy lesions


- Exacerbated by stress, winter, etc.


- A/w asthma, allergic rhinitis, multiple allergies




Tx: 1st line = topical steroids


- Mild = hydrocortisone 1-2.5%


- Medium = triamcinolone


- Benadryl


- Skin lubricants (eucerin)


- Hydrating baths followed by immediate application of eucerin




*Avoid drying skin - no hot baths, harsh soaps



Contact dermatitis

- Inflammatory skin rxn d/t contact w/ irritating external substance (i.e. poison ivy, nickel)
- Can be single lesion or generalized rash occurring w/in minutes to several hours
- Multiple, bright red, pruritic lesions evolve into bullous or vesi...

- Inflammatory skin rxn d/t contact w/ irritating external substance (i.e. poison ivy, nickel)


- Can be single lesion or generalized rash occurring w/in minutes to several hours


- Multiple, bright red, pruritic lesions evolve into bullous or vesicular lesions, easily rupture




Tx: Calamine lotion, topical steroids (i.e. triamcinolone) ointment over cream


- Severe (>20% affected, or involving face, hands, genitals prescribe a systemic corticosteroid) = oral prednisone x 12-14 days

Bacterial

Impetigo


Cellulitis


Follicular: folliculitis, furuncle, carbuncle, hidradenitis suppurative

Impetigo

- Acute superficial skin infection (S. pyrogenes or S. aureus)
- Very contagious, pruritic, common warm & humid weather
- 2 types: bullous & nonbullous forms

- Children & teens, itchy pink to red lesions that become bullous, then crusty & maculo...

BACTERIAL




- Acute superficial skin infection (S. pyrogenes or S. aureus)


- Very contagious, pruritic, common warm & humid weather


- 2 types: bullous & nonbullous forms




Nonbullous


- Erythematic macule rapidly evolves into vesicles or pustule, ruptures, contents dry, leaves crusted honey colored exudate


- Can use just topical abx




Bullous


- Bulla contains clear, yellow fluid that turns cloudily/dark yellow


- Rupture easily (1-3 days) leaving rim of scale around red, moist base


- Requires systemic abx




- Children & teens, itchy pink to red lesions that become bullous, then crusty & maculopapular -- after rupture lesions are covered w/ honey colored crusts (dried serous fluid)




Tx: Cephalexin x 10 days (allergy: z-pak), & bacitracin

Acute cellulitis

BACTERIAL



- Acute skin infection of the deep dermis & underlying tissue


- Usually caused by Gram (+) bacteria (staph)


- 2 forms: purulent & non-purulent


- Diffused pink to red colored skin, poorly demarcated margin that grows larger, lesion is hot, may be abscesses or draining of purulent green d/c



Tx: PO Clinda, Cephalexin, Doxycycline



*Erysipelas is superficial stage


- Caused by S. progenies


- Amox, z-pak

Furuncle

- Infected hair follicle that fills w/ pus
- Red bump, hot to touch

Tx: abx ointment BID & cover

BACTERIAL




- Infected hair follicle that fills w/ pus


- Red bump, hot to touch


*small abscess




Tx: I&D, warm compress, no abx unless comorb/immuno/accomp by cellulitis)

Carbuncle

- Several furuncles that coalesce to form a large boil/abscess
- Hot, tender to touch
- C&S 

Tx: 
- Non-MRSA, nonpurulent: dicloxacillin x 10 days (cephalexin or clinda)
- PCN allergy: macrolids, 2nd gen cephalosporins, clinda
- Suspect MRSA: ...

BACTERIAL




- Several furuncles that coalesce to form a large boil/abscess


- Hot, tender to touch


- C&S


- Purulent drainage




Tx:


- Non-MRSA, nonpurulent: dicloxacillin x 10 days (cephalexin or clinda)


- PCN allergy: macrolids, 2nd gen cephalosporins, clinda


- Suspect MRSA: bactrim DS x 10 days (or doxy or clinda)


- Td booster




Follow-up: w/in 48hrs


Refer if: systemic sx (fever, toxic), worsening, not responding w/in 48hrs of tx, spreading, pt immunocompromised




Complications: osteomyelitis, septic arthritis, sepsis

Hidradenitis suppurative

BACTERIAL

aka acne inversa

- Chronic follicular occlusion disorder
- Intertriginous skins (folds-axilla) -- apocrine glands
- Prevalent in women

Tx: Intralesional kenalog (corticosteroid), I&D, sometimes surgery 

BACTERIAL




aka acne inversa




- Chronic follicular occlusion disorder


- Intertriginous skins (folds-axilla) -- apocrine glands


- Prevalent in women




Tx: Intralesional kenalog (corticosteroid), I&D, sometimes surgery

Purulent (abscess/carbuncle/furuncle)

Mild


- I&D, warm compress




Moderate


- I&D, C&S


- Systemic abx: bactrim, doxycycline


- Therapy by C&S results: MRSA --> bactrim, MSSA --> dicloxacillin, or cephalexin

Nonpurulent (cellulitis/erysipelas/impetigo)

Mild


- Systemic abx: PCN, Cephalexin, Dicloxacillin, Clinda- Topical therapy indicated (impetigo only) --> mupirocin




Moderate


- IV abx: PCN, Ceftriaxone, Cefazolin, Clinda





Paronychia

- Acute local BACTERIAL skin infection of proximal or lateral nail folds that resolves after abscess drains
- Chronic cases a/w on onychomycosis

Tx: soak warm water (20min, 3x/day), apply topical abx, abscess I&D 

- Acute local BACTERIAL skin infection of proximal or lateral nail folds that resolves after abscess drains


- Chronic cases a/w on onychomycosis




Tx: soak warm water (20min, 3x/day), apply topical abx, abscess I&D

Scarlet fever

BACTERIAL
- "sandpaper" rash on face, neck, trunk, arms, legs 
- strep throat, pharyngitis
- strawberry tongue

Tx: PCN

BACTERIAL


- "sandpaper" rash on face, neck, trunk, arms, legs


- strep throat, pharyngitis


- strawberry tongue




Tx: PCN

Bites: human & animal

Human: dirtiest bites


Animals: cat bites highest rate infxn




- Need C&S


- Do not suture if high risk for infxn, or >12hrs old


- Tetanus




Tx: augmentin x 10 days (PCN allergy: clinda plus fluroquinolone)




Follow-up: 24-48hrs



Rabies: bats, raccoons, skunks, foxes, coyotes, cats --> rabies immune globulin plus rabies vaccine



Acne vulgaris

- Pustular disorder 

Mild acne: <20 comedones, or <15 inflamm lesions
- benzoyl peroxide (antibacterial) OR 
- topical retinoid

Moderate acne: 20-100 comedones, or 15-20 inflamm
- topical combo (benzoyl + retinoid) OR retinoid + benzoyl + ab...

- Pustular disorder




Mild acne: <20 comedones, or <15 inflamm lesions


- tx: TOPICAL only


- benzoyl peroxide (antibacterial) OR


- topical retinoid




Moderate acne: 20-100 comedones, or 15-20 inflamm


- tx: topical PLUS abx


- topical combo (benzoyl + retinoid) OR retinoid + benzoyl + abx




Severe acne: >5 nodules, or inflamm >50


- combo of PO abx + topical retinoid + benzoyl (consider isotretinoin (accutane))

Scabies

- communicable skin dz skin to skin contact
- place items in plastic bags for 1wk (mites don't live >3-4 days)

Tx: permethrin lotion left on for 8-14hrs 

- Communicable skin dz skin to skin contact


- Place items in plastic bags for 1wk (mites don't live >3-4 days)


- Common to see over waistband area




Tx: permethrin lotion left on for 8-14hrs

Lyme

- infection caused by b. burgdorferi, tick
- must feed on human host >24hrs to transmit spirochete

Stages:
1. Early localized dz: mild flulike sx, single annular lesion w/ central clearing (erythema migrans), resolve 3-4wks w/o tx

2. Early diss...

- infection caused by b. burgdorferi, tick


- must feed on human host >24hrs to transmit spirochete




Stages:


1. Early localized dz: mild flulike sx, single annular lesion w/ central clearing (erythema migrans), resolve 3-4wks w/o tx




2. Early disseminated infxn: months later, classic rash reappear w/ multiple lesions, usually accompanied by arthralgias, myalgia, HA, fatigue




3. Last persistent infxn: 1yr after initial infxn, MSK sx persist (joint pain, arthritis), neuropsychiatric sx (memorial probe, depression, neuropathy)




Dx: serum testing Western blot assay for IgM antibodies




Tx: antimicrobials (doxy, ceftin, amoxicillin, macrolides) 14-21 days w/ earlier dx; up to 28 days more adv dz

Burns

Tx: prevention of infection by topical abx (i.e. silvadene)

*Refer if involve high function areas (hands, feet, face, genitalia)

1st degree: skin blanches with ease

2nd degree: blisters 

3rd degree: pain minimal, white & leathery, areas surro...

*Thermal, chemical, electrical, radiation




1st degree: skin blanches with ease, dry (i.e. sunburn)




2nd degree: blisters, moist (i.e. chemical)




3rd degree: pain minimal, white & leathery, dry, areas surrounded by painful 1st & 2nd degree burns (i.e. flame)


--> REFER




Tx: prevention of infection by topical abx (i.e. silvadene)




*Refer if involve high function areas (hands, feet, face, genitalia)

Sun safety

<6mo do NOT apply sunscreen




>6mo apply minimum SPF 15 q2hrs

Viral

Herpes


Molluscum contagiosum


HPV


Pityriasis rosea


Herpetic whitlow

Varicella

VIRAL



2-3mm vesicles start on trunk then appear on limbs 2-3 days later



Nonclustered lesions at variety of stages




tx: antiviral meds (acyclovir) 24-48hrs of eruption




vaccine: varivax @ 4 & 6yo

Herpes zoster

VIRAL




typically >50yo, possible any age with hx chickenpox




vesicles in unilateral dermatomal pattern, slowly resolving w/ crusting




complications: postherpetic neuralgia, ophthalmologic involvement, superimposed bacterial infxn




tx: antivirals w/in 72hrs of eruption




*Involve EYES --> Refer!




vaccine: zostavax 1 dose @ >60yo

Molluscum contagiosum

VIRAL

- Smooth, skin colored dome-shaped, pearly papules w/ umbilicated centers
- Cause: pox virus, skin to skin, sex
- Contagious until ALL lesions disappear

Tx: q2-3wks for 6mo, curette, cryo (liquid nitrogen), imiquimod

VIRAL




- Smooth, skin colored dome-shaped, pearly papules w/ umbilicated centers


- Cause: pox virus, skin to skin, sex


- Contagious until ALL lesions disappear




Tx: q2-3wks for 6mo, curette, cryo (liquid nitrogen), imiquimod

HPV

VIRAL



Verruca vulgaris (common warts)


- OTC: salicylic acid


- Face: tretinoin


- Genital: imiquimod




Verruca plantaris (plantar warts)




Verruca planae (flat warts, HPV3)


- Children, young adults


- Forehead, cheeks, nose, perioral


- Common cause: shaving


- Tx: imiquinod topical




Condyloma acuminata (genital warts)


- Rough on surface, worse during preg

Pityriasis rosea

VIRAL




- Common children & 15-40yo


- Self limiting viral exantham


- Sometimes a/w URI


- HAROLD PATCH start on trunk --> develops smaller lesions on body, 50% pruritus, lasts 5-8wks




Tx: symptomatic, calamine lotion, antihistamin, topical/oral steroids

Herpetic whitlow

VIRAL

- skin infection of finger(s) caused by herpes I or 2
- direct contact

Tx: self-limiting

VIRAL




- skin infection of finger(s) caused by herpes I or 2


- direct contact




Tx: self-limiting

Measles

VIRAL

aka rubeola
- fever, malaise, 3 c's: coryza, cough, conjunctivitis
- Koplik's spots: small, white round spots on base of buccal mucosa
- Sx: don't appear until 10-14 days after exposure: cough, runny nose, inflamed eyes, sore throat, feve...

VIRAL




aka rubeola


- fever, malaise, 3 c's: coryza, cough, conjunctivitis


- Koplik's spots: small, white round spots on base of buccal mucosa


- Sx: don't appear until 10-14 days after exposure: cough, runny nose, inflamed eyes, sore throat, fever, & a red, blotchy skin rash




Tx: none

Fifth's disease

Parvovirus 19
- 5-15yo
- URI sx 1st

RASH
1. slapped cheeks
2. maculopapular rash on extremities
3. rash subsides, painful/swollen joints

Parvovirus 19


- 5-15yo


- URI sx 1st




RASH


1. slapped cheeks


2. maculopapular rash on extremities


3. rash subsides, painful/swollen joints

Coxsackie virus

VIRALaka hand, foot, mouth dz
- Enterovirus
- sore throat, rash, blisters
- fever, oral vesicles on buccal mucosa & tongue
- lesions on palms, plantar surface of feet, buttocks
VIRAL

aka hand, foot, mouth dz




- Enterovirus


- sore throat, rash,


blisters


- fever, oral vesicles on buccal mucosa & tongue


- lesions on palms,


plantar surface of feet, buttocks

Fungal

Tinea capitus


Tinea corporis


Tinea cruris


Tinea pedis


Tinea/pityriasis versicolor


Intertrigo


Onychomycosis

Tinea capitus
FUNGAL

aka ringworm of the scalp
Sx:
- Scalp, broken hair shafts
- versus alopecia (has NO black dots, hair shafts)
- pruritic
- a/w scalp injury, moist hair, poor hygiene
- Kerion: swollen, boggy, fever, pain, lymph, pus --> steroids

Dx: KOH -...

FUNGAL




aka ringworm of the scalp


Sx:


- Scalp, broken hair shafts


- versus alopecia (has NO black dots, hair shafts)


- pruritic


- a/w scalp injury, moist hair, poor hygiene


- Kerion: swollen, boggy, fever, pain, lymph, pus --> steroids




Dx: KOH --> hyphae




Tx: Griseofulvin PO, antifungal shampoo, topical Rx ineffective as monotherapy!

Tinea corporis
FUNGAL

aka ringworm
- body
- pruritic, circular, red, scaly patch
- CENTRAL CLEARING
- well demarcated
- Common: adults caring peds w/ T. captius, athletes skin-skin, immunosupp.

Tx: topical antifungal imidazole (if immunosupp PO lamisil (monit...

FUNGAL




aka ringworm


- body


- pruritic, circular, red, scaly patch


- CENTRAL CLEARING


- well demarcated


- Common: adults caring peds w/ T. captius, athletes skin-skin, immunosupp.




Tx: topical antifungal imidazole (if immunosupp PO lamisil (monitor liver)

Tinea cruris

"jock itch" groin
- small, red patch w/ crust & scaling --> spreads peripherally w/ curved well defined edges

Tx: topical antifungal (lotrimin, lamisil), zeazorb powder, PO 2wks if severe 

"jock itch" groin


- small, red patch w/ crust & scaling --> spreads peripherally w/ curved well defined edges




Tx: topical antifungal (lotrimin, lamisil), zeazorb powder, PO 2wks if severe

Tinea pedis

FUNGAL

"feet"
- moisture, poor vent in shoes
- can cause t. cruris
- may be a/w onychomycosis
- macerated hyperkeratotic plaques in interdigital webs OR dull redness w/ scaling on plantar

Tx: topical econazole, severe: oral, KEEP DRY!

FUNGAL




"feet"


- moisture, poor vent in shoes


- can cause t. cruris


- may be a/w onychomycosis


- macerated hyperkeratotic plaques in interdigital webs OR dull redness w/ scaling on plantar




Tx: topical econazole, severe: oral, KEEP DRY!

Tinea/pityriasis versicolor

YEAST

- chronic, asx, warm climates, fine scaly guttate OR nummular patches, yellow-brown macules
- hypopigmented on dark skin
- NEVER on face or legs

Tx: PO ketoconazole, selenium sulfide OR ketoconazole shampoo, topical

YEAST




- chronic, asx, warm climates, fine scaly guttate OR nummular patches, yellow-brown macules


- hypopigmented on dark skin


- NEVER on face or legs




Tx: PO ketoconazole, selenium sulfide OR ketoconazole shampoo, topical

Superficial candidiasis

- Superficial skin infection from yeast


- Inc w/ warmth/humidity, friction, dec immunity


- Infects skin (candidal intertrigo), mucous membranes (thrush, vaginitis), and systemically




Sx:


- External: bright red & shiny lesions, itch, burn, can be under breast, may have satellite lesions (small red rashes around the main rash)


- Oral thrush: severe sore throat w/ white adherent plaques w/ red base --> give oral nystatin




Tx: Nystatin powder &/or cream in skin folds




*HIV esophageal candida infxns treated w/ systemic antifungals

Intertrigo

CANDIDA

- mucosal surfaces &/or skin folds
- Rxs: obese, DM, recent abx, or steroids, immunosupp, chronic moisture
- erythema erosions, tissues, itchy, burn

Tx: topical antifungal, nystatin or imidazole ointment, zeazorb powder

CANDIDA




- mucosal surfaces &/or skin folds


- Rxs: obese, DM, recent abx, or steroids, immunosupp, chronic moisture


- erythema erosions, tissues, itchy, burn




Tx: topical antifungal, nystatin or imidazole ointment, zeazorb powder

Onychomycosis


- aka dermatophytosis of the nail
- chronic disfiguring disorder of the nail
- nails are dull, thickened, lusterless

Dx: hyphae of nail scrapings mixed with KOH

Tx: antifungals (diflucan)

FUNGAL




- aka dermatophytosis of the nail


- chronic disfiguring disorder of the nail


- nails are dull, thickened, lusterless




Dx: hyphae of nail scrapings mixed with KOH




Tx: antifungals (diflucan, lamisil)

Kawasaki disease

Unknown origin

Sx:
- Early stages: rash & fever, peeling skin on palms & bottom of feet
- Late stages: inflamm of medium size blood vessels (vasculitis). It also affects lymph nodes, skin, & mucous membranes, such as inside the mouth

Tx: sympt...

Unknown origin




Sx:


- Early stages: rash & fever, peeling skin on palms & bottom of feet


- Late stages: inflamm of medium size blood vessels (vasculitis). It also affects lymph nodes, skin, & mucous membranes, such as inside the mouth




Tx: symptomatic

Infant derm

Hemangioma


- benign tumor of endothelium


- often NOT present @ birth


- rapid growth from day 1-6mo


- tx: po propranolol or systemic corticosteroids to slow growth; watchful waiting




Port wine lesion


- present @ birth


- blanch able red to dark pink


- will darken as child grows, does NOT regress!




Mongolian spots


- blue-black macular flat lesions usually buttocks


- most common: asians, AA, NA


- lightens over time, NO tx




Milia


- raised white bumps on nose or cheeks


- No tx, resolve few weeks on own




Erythema toxic neonatorum


- occasionally present @ birth, usually appear 1st 48hrs of life (resolves 5-7 days)


- erythematous papules progress or pustular lesions


- No tx, resolves on own




Acne neonatorum


- androgens from mother or infant


- face, lesions start 1st mo, lasts 1-2mo, self-limiting




Atopic dermatitis/eczema


- present @ birth to 2yo


- hydrate w/ daily ointment




Seborrheic dermatitis (cradle cap)


- scalp, face, groin, underarms


- erythematous plaque/scales, common 3wks-12mo


- apply emollient overnight, can remove w/ soft brush in AM




Keratosis pilaris


- genetic, acne like tiny bumps on skin, common outer aspect of upper arm


- rough skin texture, asx or itch


- NO cure, use mild soapless cleansers to prevent dryness


- childhood & adolescence: improves w/ age, periods of remission & exacerb, worse in cold/dry weather

Acanthosis nigricans

- hyper pigmented velvety plaque on skin fold areas (neck, axilla)
- d/t insulin resistance or inherited, DM

- hyper pigmented velvety plaque on skin fold areas (neck, axilla)


- d/t insulin resistance or inherited, DM

Ointment

Do NOT use ointment in intertriginous areas or perineum

Cafe au lait spots

>5 should be concerned, can indicate


neurofibromatosis type I