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13 Cards in this Set
- Front
- Back
Freud (1917) |
Mourning and Melancholia - key = loss Potential for adult depression is created by loss in early childhood |
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Brown and Harris (1978) |
Loss of a parent before the age 11 is a key risk factor for depression |
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Borwn et al (1968_ |
List of thing which shape self-esteem |
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Burman et al (1988) |
Of the adults who were sexually abused as children; 18% suffered from depression |
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Weiss et al 1999 |
Early stressors cause long-term dysregulation of the HPA (Hypothalamic-pituitary-adrenal) axis leading to increased cortisol response, in both human and animals These changes remain detectable in adulthood |
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Aaron Beck (1967) |
Early loss, emotional abuse and excessive criticism Depression is caused by maladaptive thought process |
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Abramson, Teasdale, Seligman (1978) |
Attribution theory Global vs specific; stable vs unstable; internal vs external factors |
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Arrango et al (2003) |
SNPs in the 5-HTTLPR allele predicts suicidal behaviour |
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Maes et Meltzer (1996) |
Reduced serotonin metabolites (5-HIAA) and precursors (tryptophan) in depresssion |
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Angst 1988 |
50% of patients who recover through medication (SSRI) relapse within 2 years |
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Drevets et al (1997)
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The subgenual ACC is under active are reduced in volume in both unipolar and bipolar depression |
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Harir et al (2003) |
Volunteers with the short allele of the serotonin transporter (5HTTLPR) polymorphism show increased amygdala responses to fearful faces |
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Sheline et al (2004) Fu et al (2004) |
in patients with depression, the fearful amygdala response to fearful faces is reduced by 8 week SSRI treatment |