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15 Cards in this Set
- Front
- Back
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what drugs do not cross the BBB?
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CEPHALOSPORINS ( 1& 2nd gen)
CLINDAMYCIN |
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what drug is commonly used with sulfonamides
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Trimethoprim
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What are pencillinase-resistant pencillins used for ?
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S.aureus
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The prophalaxis for syphilis?
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Benzathine penicillin G
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The Mechanism of action sof penicillin is
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Inhibits the cellwall snthesis
- bactericidal |
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anti-pseudomonal penicillins are
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CPT=carbenicillin,piperacillin,Ticarcillin.
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The rifampin acts by
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inhibiting the DNA dependent RNA polymerase
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The vancomycin causes the following toxicities
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Nephrotoxicity,Ototoxicity,
thrombo-plebitis and red man/neck syndrome. |
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prophalaxis for recurrent urinary tract infections is
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Trimepthoprim and Sulfamethoxazole.
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The clindamycin is used to treat the
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anerobes above the diaphram
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Aminoglycosides are not effective on
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anerobes
/genatamycin,neomycin,amikacin and streptomycin. Nephrotoxicity,ototoxicity and teratogen. |
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The mechanism of action of
Floroquinolones is |
Inhibit DNA gyrase ( tropoisomerase II )
Bactericidal |
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The elimination pathways of tetracycline is and that of doxycycline is
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Tetracycline is - Renal
Doxycycline is - hepatic |
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What are macrolides -
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ACE - code word
Azithromycin,clarithromycin and Erthromycin |
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The mechanism of action of clindamycin is
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Bacteriosttaic and it blocks peptide bond formation at the 50 s ribosomal unit.
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