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30 Cards in this Set
- Front
- Back
the fluoride story
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detrimental effects of fluoride on tooth appearance-->scientific invesitgation-->discovery of anticaries benefits
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The Fluroide Story
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References to fluorosis throughout history:
-dating back to 1st century greeks Anticariogenic properties: -europe, late 19th centruy -Fl powders and pills to fight caries -very little scientific basis |
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Who Identify the scientific basis for fluoride in caries prevention
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-Frederick McKay
-H. Trendley Dean |
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George McKay:
When did he graduate: where did he work? what did he observe? what did he note? impact on him? |
-1901
-Worked Colorado -Observed "Colorado Brown Stain" -Later noted no reference to brown stain in dental literature -piqued his curiosity |
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McKay 1909:
who did he consult? what kind of sutdies did he conduct end result? |
-GV black, enamel expert; but orignally he thought it was unimportnat
-Epi studies by McKay in Colorado: 90% of children affected w/ fluross -Histological study by Black; |
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Blacks contribution?
puzzle by? |
-black raised profile of ottled enamel in research community
-mottled enamel was hypocalcified, should have high susceptibilit yot decay but didn't |
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colorado-like teeth?
localized to? suspected what issue? |
-other states and countries
-children born in specific geographic -McKay suspected water supply as etiologic factor -kids with brown stained teeth were clustered in certain geographical areas |
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Mckay tests his theory when and where?
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-1923
-Oakley Idaho |
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CO Brown teeth in oakley idaho
-appeared after? -what did he recommend? -the result? |
-new water pipelin built in 1908
-1923: Mckay recommends finding an alternate water source -ten years late rproblem gone |
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Another city?
-situation? -flurorisis situation -water samples? -chemist finds? |
-owned by Aluminum Company of America-everyone in town employed by company
-bauxite kids-mottled enamel, kids 5mi away-normal enamel -Mckay's Bauxite water samples-normal -ALCOA chemist analysis: high fluoride content |
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H.T. Dean/USPHS
job? found? |
-traveled U.S. recoridng prevalence and severity of mottled enamel relative to Fl in water
-IDed clear dose-response relationship between fluroide in water and decay ppl would get -For Fl up to 1 ppm, extend and severity of mottling is of no public health concern -For Fl |
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Findings of McKay, Dean and USPHS
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-foundation for research confirming caries prevention efficacy of community and water fluoridation:
fluoride in right amounts is good at prevneting caries |
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Normal Enamel Formation
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1. Pre-eruption enamel is initially
-protein-rich -20% mineralized -seeded with HA crystals 2. Matrix Proteins break down, replaced by Ca & PO4 precipitating onto growing crystal surfaces 3.Matures slowly inot highly(96%) mineralized tiusse via crystal growth-->very little organic protein remains |
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fluorosis pathogensis
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-excess fluoride probably:
-slows down breakdown of matrix proteins -slows removal of protein by-products:toom much protein hanging around for too long, HA can't replace it. -Retarded crystal growth -hypomineralized enamel |
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What does flurosis produce?
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-hypomineralized enamel in an otherwise normal enamel matrix
-enamel matrix just doesn't go away fast enough, everything else is normal(ameloblasts, matrix proteins |
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Has Fl been shown to cause hypoplastic changes?
then why does pitting and enamel occur? |
-no
-occurs posteruptively |
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Why isn't hypomineralized enamel decayed?
Why is fluorsis teeth not soft? Why is there brown decay in fluorosis |
-antibacterial effect
-post eruption enamle maturation -calcium and phosphate uptake from saliva post-eruption which leans to enamel increase in density -fluoride retards enamel matrix removal, once erupts through, nothing preventing enamel from taking up Ca, PO4 in saliva-->get harder skin on tooth -Exogenous sources: foods, uptake into porous enamel prior to post-eruption maturation -teeth do not reupt with brown stains |
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Fluorosis index?
White areas are...? occur in? |
thylstrup Fejerskov index
-not limited to areas of plaque accumulation(as in white sport caries lesions) -areas of non-plaque accumualtion areas |
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Treatment of Flurosis?
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-enamel microabrasion
-remineralization |
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enamel Microabrasion
inventor? uses ___ to ___ purpose? |
Dr. Theodore Croll
-abrasive paste: pumice + HCL -controlled removal of outer enamel -remove brown discoloration on out levels of enamel, hypomineralization is most severe at surface |
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Enamel Microabrasion:
Products: -Opalustre -Prema |
-Opalustre(ultradent)
-Prema(practicon) |
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Enamel Microabrasion:
Technique: |
-eye protection for patient
-rubber dam -prophy cup, LOW RPM -Apply for sec. rinse -assess for contour change: convexity, stop or continue knowing can fill convexity with composite -repeat -topical fluroide application to return teeth to normal mineralization |
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Common area with flurosis?
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Zacatecas, Aguacalientes Mexico
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Minimally Invasive treatments for white spot lesions
only used when? |
-remineralize lesion rather than remove superficial area
-can be applied to fluorissi and incipient carious white spots only when surface is intact |
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Amorphous calcium phosphate stabilized by?
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Casein Phosphopeptides, CPP-ACP
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Remineralized enamel with 1000ppm fluroide
translucency? mineral? |
-densifies outer surface but doesn't penetrate deep enough to restore mienral underneth
-makes surface more resistant to acid dilution -changes translucency slightly at surface -+7% mineral |
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Remineralised enamel with 2% CPP-ACP
fxnatliy? penetrates through? mineral? |
-Ca, PO4 can penetrate deeper and restore translucency
-remineralisation throguh body of lesion -+13% mineral |
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Remineralised with enamel 2% CPP-ACPF
reminerlisation through? mineral? |
Ca, PO4 and fluroide working togehter can penetrate deeper
-remineralisation through body of lesion, enamel is now also more acid resistant +21% mineral |
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Mild Fluorosis
Fluoride rich where? need to ___ via? then? |
enamel surface
break seal via acid etching to remove pumus now much able to absorb Fl, Ca, PO4 |
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Fluoridation of water supplies
ideal fluoride concentration is fluoridinated water necessary? |
-controversial, when safe effectivness is overwhelming
-.7-1.2ppm considered ideal fluoride, not changed to .7 -increased in other sources of fluoride |