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30 Cards in this Set

  • Front
  • Back
the fluoride story
detrimental effects of fluoride on tooth appearance-->scientific invesitgation-->discovery of anticaries benefits
The Fluroide Story
References to fluorosis throughout history:
-dating back to 1st century greeks

Anticariogenic properties:
-europe, late 19th centruy
-Fl powders and pills to fight caries
-very little scientific basis
Who Identify the scientific basis for fluoride in caries prevention
-Frederick McKay
-H. Trendley Dean
George McKay:
When did he graduate:
where did he work?
what did he observe?
what did he note?
impact on him?
-1901
-Worked Colorado
-Observed "Colorado Brown Stain"
-Later noted no reference to brown stain in dental literature
-piqued his curiosity
McKay 1909:
who did he consult?
what kind of sutdies did he conduct
end result?
-GV black, enamel expert; but orignally he thought it was unimportnat

-Epi studies by McKay in Colorado: 90% of children affected w/ fluross

-Histological study by Black;
Blacks contribution?
puzzle by?
-black raised profile of ottled enamel in research community

-mottled enamel was hypocalcified, should have high susceptibilit yot decay but didn't
colorado-like teeth?
localized to?
suspected what issue?
-other states and countries

-children born in specific geographic

-McKay suspected water supply as etiologic factor

-kids with brown stained teeth were clustered in certain geographical areas
Mckay tests his theory when and where?
-1923
-Oakley Idaho
CO Brown teeth in oakley idaho
-appeared after?
-what did he recommend?
-the result?
-new water pipelin built in 1908
-1923: Mckay recommends finding an alternate water source
-ten years late rproblem gone
Another city?
-situation?
-flurorisis situation
-water samples?
-chemist finds?
-owned by Aluminum Company of America-everyone in town employed by company

-bauxite kids-mottled enamel, kids 5mi away-normal enamel

-Mckay's Bauxite water samples-normal

-ALCOA chemist analysis: high fluoride content
H.T. Dean/USPHS

job?

found?
-traveled U.S. recoridng prevalence and severity of mottled enamel relative to Fl in water

-IDed clear dose-response relationship between fluroide in water and decay ppl would get

-For Fl up to 1 ppm, extend and severity of mottling is of no public health concern


-For Fl
Findings of McKay, Dean and USPHS
-foundation for research confirming caries prevention efficacy of community and water fluoridation:
fluoride in right amounts is good at prevneting caries
Normal Enamel Formation
1. Pre-eruption enamel is initially
-protein-rich
-20% mineralized
-seeded with HA crystals

2. Matrix Proteins break down, replaced by Ca & PO4 precipitating onto growing crystal surfaces

3.Matures slowly inot highly(96%) mineralized tiusse via crystal growth-->very little organic protein remains
fluorosis pathogensis
-excess fluoride probably:
-slows down breakdown of matrix proteins
-slows removal of protein by-products:toom much protein hanging around for too long, HA can't replace it.
-Retarded crystal growth
-hypomineralized enamel
What does flurosis produce?
-hypomineralized enamel in an otherwise normal enamel matrix
-enamel matrix just doesn't go away fast enough, everything else is normal(ameloblasts, matrix proteins
Has Fl been shown to cause hypoplastic changes?

then why does pitting and enamel occur?
-no

-occurs posteruptively
Why isn't hypomineralized enamel decayed?

Why is fluorsis teeth not soft?

Why is there brown decay in fluorosis
-antibacterial effect
-post eruption enamle maturation
-calcium and phosphate uptake from saliva post-eruption which leans to enamel increase in density

-fluoride retards enamel matrix removal, once erupts through, nothing preventing enamel from taking up Ca, PO4 in saliva-->get harder skin on tooth

-Exogenous sources: foods, uptake into porous enamel prior to post-eruption maturation

-teeth do not reupt with brown stains
Fluorosis index?

White areas are...?

occur in?
thylstrup Fejerskov index

-not limited to areas of plaque accumulation(as in white sport caries lesions)

-areas of non-plaque accumualtion areas
Treatment of Flurosis?
-enamel microabrasion
-remineralization
enamel Microabrasion
inventor?
uses ___ to ___

purpose?
Dr. Theodore Croll

-abrasive paste: pumice + HCL
-controlled removal of outer enamel

-remove brown discoloration on out levels of enamel, hypomineralization is most severe at surface
Enamel Microabrasion:
Products:
-Opalustre
-Prema
-Opalustre(ultradent)
-Prema(practicon)
Enamel Microabrasion:
Technique:
-eye protection for patient
-rubber dam
-prophy cup, LOW RPM
-Apply for sec. rinse
-assess for contour change: convexity, stop or continue knowing can fill convexity with composite
-repeat
-topical fluroide application to return teeth to normal mineralization
Common area with flurosis?
Zacatecas, Aguacalientes Mexico
Minimally Invasive treatments for white spot lesions

only used when?
-remineralize lesion rather than remove superficial area

-can be applied to fluorissi and incipient carious white spots only when surface is intact
Amorphous calcium phosphate stabilized by?
Casein Phosphopeptides, CPP-ACP
Remineralized enamel with 1000ppm fluroide

translucency?
mineral?
-densifies outer surface but doesn't penetrate deep enough to restore mienral underneth

-makes surface more resistant to acid dilution

-changes translucency slightly at surface

-+7% mineral
Remineralised enamel with 2% CPP-ACP

fxnatliy?
penetrates through?
mineral?
-Ca, PO4 can penetrate deeper and restore translucency

-remineralisation throguh body of lesion

-+13% mineral
Remineralised with enamel 2% CPP-ACPF

reminerlisation through?

mineral?
Ca, PO4 and fluroide working togehter can penetrate deeper

-remineralisation through body of lesion, enamel is now also more acid resistant

+21% mineral
Mild Fluorosis
Fluoride rich where?
need to ___ via?
then?
enamel surface

break seal via acid etching to remove pumus

now much able to absorb Fl, Ca, PO4
Fluoridation of water supplies

ideal fluoride concentration

is fluoridinated water necessary?
-controversial, when safe effectivness is overwhelming

-.7-1.2ppm considered ideal fluoride, not changed to .7

-increased in other sources of fluoride