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12 Cards in this Set

  • Front
  • Back
Surface markings of the liver
Diaphragm above, Top level around 5/6th ribs, Right upper quandrant, Lower border behind lower ribs, Right tip extending past the midline
Anatomical relations of the pancreas
Retroperitoneal, Head near 1st, 2nd and 3rd parts of duodenum, Body anterior to L2 and L3, Tail anterior to left kidney
Name 4 factors controlling gastric acid secretion
Vagus nerve

Gastrin


Histamine


Secretin inhibits release

2 sites of bleeding that lead to haematemesis
oesophageal varices, gastric ulcer
Hormonal influences on controlling synthesis and breakdown of fat in adipocytes
Hormone sensitive lipase (HSL) breaks down fat to FAs

Adrenaline, glucocorticoids, ACTH and glucagon tigger HSL release


Insulin deactivates HSL


Insulin activates lipoportein lipase, which results in increase of TAGs

Hormonal influences controlling the level of glucose in the blood
Insulin released in response to high blood glucose

Insulin lowering blood glucose by uptake to tissues


Glucagon and adrenaline are released in reponse to low blood glucose triggering glycogenolyiss and gluconeogenesis

Name teh enzyme that warfarin inhibts and its substrate
Vitamin K epoxide, Vitamin K
List 4 factors that might contribute to constipation
Bedbound

Poor appetite


Dehydration


Opiates


Hypercalcaemia

Name 2 diseases that might lead to failure of absorption of fat and explain the mechanism
- Blockage of pancreatic exocrine secretion (Pancreatitis, carcinoma of the head of pancreas, cystic fibrosis) - pancreatic lipase secretion is reduced so there is not fat digestion

- Coeliac disease - atrophy of intestinal wall that reduced absorptive area


- Complete blockage of bile secretion or production - no bile salts in intestine to absorb fats.

Name 3 physiological effects of bile
Excretion of conjugated toxinsFormation fo fat micelles to aid lipid digestionExcretion of cholesterol
Name 3 possible complications of gall stone disease
Cholecystitis, Cholangitis, Pancreatitis
List 3 lifestyle factors that predispose to gall stone formation
Obesity, Low-calorie diet, Age