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15 Cards in this Set
- Front
- Back
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What does the VITAMINS acronym for causes of dementia stand for? |
Vascular Infectious Trauma Autoimmune Metabolic Iatrogenic Neoplasm Seizure |
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What is the most common cause of dementia? |
Alzheimer's disease |
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What are the next 2 common causes of dementia besides AD? |
- Lewy body dementia - Vascular dementia |
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What is amyloid made of? |
A-beta-42 |
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What neurotransmitter is deficient in AD patients? |
Acetylcholine |
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What percentage of AD cases are familial? |
5% |
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What are 3 genes involved in AD risk? |
- CLU - CR1 - PICALM |
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What part of the brain is the main source of acetylcholine? |
Nucleus basalis of Meynert |
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What kind of protein is beta-amyloid? |
Transmembrane protein |
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What is Tau protein's function? |
To stabilize or repair microtubules |
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What scale tests for Alzheimer's dementia?
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Mini-mental Status Exam (MMSE) |
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What is REM sleep disorder? How is REM sleep disorder treated? |
Acting out dreams as a result of Lewy Body Dementia
Clonazepam |
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What protein is over-represented in Lewy Body Dementia? |
Alphasynuclein |
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What is the treatment of DLB? |
Acetylcholine esterase inhibitors |
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Name 2 acetylcholine esterase inhibitors |
- Donepezil - Rivastigmine |
