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22 Cards in this Set

  • Front
  • Back
What are the 4 significant impairments in cognitive disorders
memory
judgement
language
attention
Delirium is characterized by
short-term confusion and changes LOC
what are the four subcategories based on several causes of delirium
substance induced
general medical condition (infection)
multiple etiologies (head trauma, disease)
Delirium NOS (sleep deprivation)
What is dementia, and what two things are normal?
marked by severe impairment in memory, judgement and orientation despite a NORMAL level of alertness and arousal.
what are the six subcategories of dementia
Alzheimers type (progressive intellectual deterioration)
vascular dementia
other medical conditions such as AIDS or head trauma
substance induced (toxin or med)
multiple eitiologies
NOS
What are amnesic disorders
memory loss without cognitive impairment
In the Clinical examination- what type exam do you look for in a physical exam
neuro exam
during the MSE

carefully evaluate
cognition
what are non-specific signs of brain dysfunction
intellectual, memory and cognitive impairment

(pause in thought, lack of intellectual ability, perservation, poor judgement)

Alterations in LOC

Change in personality

disinhibition

poverty of speech

visual hallucinations prominant

MOOD may initially be depressed, anxious, labile but may progress to apathy

affect, shallow, and flat
What clinical evaluation will you perform as a screening assessment of cognition
orientation to time and place and person

calculation- subtract from 7

remember the names of a few objects from a few minutes ago

language, repetition of words, writing a sentence

abstraction- interpret a proverb
visuospatial copying a design
what labs would you get
CBC
electrolytes
RBC folate
THY
drug screen
liver enzymes
what other testing would you do for dementia?
psychological testing

skull xray, EEG, CT, MRI, lumbar puncture, brain scan and angiography
what is the hallmark symptom of delirium (definition)
impairment of consciousness, usually accompanied by global impairments of cognitive functions, associated with emotional lability, hallucinations or illusions, inappropriate, impulsive, irrational, violent behavior
WHAT are the KEY features or S/S of delirium
altered consciousness with hyperarousal or hypoarousal with agitation or apathy

disorientation

memory impairment

illogical speech

perceptual disturbance (auditory, visual and tactile hallucinations)
SEVER emotional lability
REVERSED sleep wake cycle or fragmented sleep

associated Neuro symptoms- incoordination, dysphagia, tremor, asterixis, ataxia and apraxia
What is the differential diagnosis for delirium vs. dementia
Changes in dementia are more stable over time and do not fluctuate over the course of the day.

dementia pts are more alert

delerium are more clouded
There is a ___ month mortality rate of __% and __% in patients who have an episode of delirium

___ year mortality rate of ___%
3 month 23-33%

1 year 50%
treatment of delirium
PRIMARY goal is to identify and treat the underlying cause, correct the metabolic abnormalities, ensure proper hydration, electrolyte balance and nutrition. Basically identify the cause

LOW doses of high potency antipsychotics may be used for agitation (2-5mg haldol)

Benzos for agitation

rare intractable cases, ECT
what is the definition of dementia
decrease in cognition in the setting of a stable level of consciousness
what are the effected functions in someone with dementia
intelligence
language
problem solving
memory
learning
orientation
perception
attention
judgement
concentration
social abilities
what are the signs and symptoms of dementia
major deficits in

orientation
memory
perception
intellectual functioning and reasoning

marked changes in personality, affect, and behavior

commonly associated with hallucinations 20-30% of patients and delusions in 30-40% of patients

symptoms of depression are present in 40-50% of patients with dementia
what is the diagnostic criteria for dementia due to "other medical condition" such as head trauma, HIV, Huntingtons disease, Picks disease
1) memory impairment
2) one or more of the following
aphasia- language disturbance
apraxia- impaired ability to carry out motor activities despite good motor function)
agnosia- failure to recognize or identify objects even if good sensory function)
disturbance in executive functioning (planning, organizing, sequencing, abstracting)
what is included in a thorough workup of dementia
physical exam and neuro exam
VS
MSE
review of meds and med levels
Blood and urine screen

Blood work
electrolytes
liver and renal function
SMA-12 or chem profile
urinalysis
CBC with diff
TSH
RPR
FTA-ABS if CNS disease expected
B12
folate levels
urine corticosteriods
ESR
ANA
Arterial blood gas
HIV
Urine pophobilinogens
chest radiograph
EKG
CT
MRI
SPECT
lumbar puncture
EEG
neuropsych testing